Patents by Inventor Uma Shrestha

Uma Shrestha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Solid dispersion comprising a highly substituted hydroxyalkyl methylcellulose
    Patent number: 9962446
    Abstract: A solid dispersion comprising at least one active ingredient in at least one hydroxyalkyl methylcellulose having a DS of from 1.0 to 2.7 and an MS of from 0.40 to 1.30, wherein DS is the degree of substitution of methoxyl groups and MS is the molar substitution of hydroxyalkoxyl groups, can be produced by extrusion or spray-drying.
    Type: Grant
    Filed: July 12, 2013
    Date of Patent: May 8, 2018
    Assignee: Dow Global Technologies LLC
    Inventors: Nicholas S. Grasman, Steven J. Guillaudeu, Mark J. Hall, Uma Shrestha, Maureen L. Rose, William W. Porter, III, Wesley J. Spaulding, Kevin P. O'donnell, True L. Rogers
  • Biologically active composition comprising ethylcellulose
    Patent number: 9198865
    Abstract: A biologically active composition comprising an ethylcellulose, a polyethylene oxide and a biologically active ingredient, wherein the amount of ethylcellulose is at least about (15) percent, based on the total weight of the composition, can be used in melt-extrusion processes to produce pharmaceutical dosage forms.
    Type: Grant
    Filed: November 17, 2006
    Date of Patent: December 1, 2015
    Inventors: Mark J. Hall, Karen A. Coppens, Pamela S. Larsen, Shawn A. Mitchell, Michael D. Read, Uma Shrestha
  • SOLID DISPERSION COMPRISING A HIGHLY SUBSTITUTED HYDROXYALKYL METHYLCELLULOSE
    Publication number: 20150140091
    Abstract: A solid dispersion comprising at least one active ingredient in at least one hydroxyalkyl methylcellulose having a DS of from 1.0 to 2.7 and an MS of from 0.40 to 1.30, wherein DS is the degree of substitution of methoxyl groups and MS is the molar substitution of hydroxyalkoxyl groups, can be produced by extrusion or spray-drying.
    Type: Application
    Filed: July 12, 2013
    Publication date: May 21, 2015
    Applicant: Dow Global Technologies LLC
    Inventors: Nicholas S. Grasman, Steven J. Guillaudeu, Mark J. Hall, Uma Shrestha, Maureen L. Rose, William W. Porter, III, Wesley J. Spaulding, Kevin P. O'donnell, True L. Rogers
  • MELT-EXTRUDED FILM
    Publication number: 20110236465
    Abstract: A mono-layer or multi-layer film wherein at least one of the layers has a thickness of at least 0.125 mm is produced from a melt-extruded polymer composition comprising a) a water-soluble polymer, b) an active ingredient and c) an adjuvant selected from the group consisting of mono- and disaccharides, sugar alcohols, low molecular weight water soluble polymers, and salts of cross-linked carboxymethylcellulose, with the proviso that the adjuvant c) is different from the water-soluble polymer a).
    Type: Application
    Filed: February 25, 2011
    Publication date: September 29, 2011
    Inventors: Mark J. Hall, Michael D. Read, Uma Shrestha
  • MULTILAYER MELT-EXTRUDED FILM
    Publication number: 20110236443
    Abstract: High amounts of active ingredients, such as drugs, can be incorporated into a multilayer melt-extruded film which comprises i) one or more active ingredient layers produced from a melt-extruded polymer composition comprising a) a water-soluble polymer and b) an active ingredient; and ii) one or more removable protective layers which leave the active ingredient layer(s) substantially intact upon removal of the protective layer(s).
    Type: Application
    Filed: February 25, 2011
    Publication date: September 29, 2011
    Inventors: Mark J. Hall, Karen A. Coppens, Michael D. Read, Uma Shrestha
  • MELT-EXTRUDED FILM
    Publication number: 20110236666
    Abstract: A melt-extruded film is produced by a process which comprises the steps of blending a) a water-soluble polymer, b) an active ingredient, and c) optional additives and subjecting the blend to melt-extrusion to produce an extruded melt and drawing the extruded melt at a draw-down ratio of from 1.5 to 20 to a film of a thickness of at least 0.04 mm.
    Type: Application
    Filed: February 25, 2011
    Publication date: September 29, 2011
    Inventors: Mark J. Hall, Michael D. Read, Uma Shrestha
  • BIOLOGICALLY ACTIVE COMPOSITION COMPRISING ETHYLCELLULOSE
    Publication number: 20090130058
    Abstract: A biologically active composition comprising an ethylcellulose, a polyethylene oxide and a biologically active ingredient, wherein the amount of ethylcellulose is at least about (15) percent, based on the total weight of the composition, can be used in melt-extrusion processes to produce pharmaceutical dosage forms.
    Type: Application
    Filed: November 17, 2006
    Publication date: May 21, 2009
    Inventors: Mark J. Hall, Karen A. Coppens, Pamela S. Larsen, Shawn A. Mitchell, Michael D. Read, Uma Shrestha