Patents by Inventor Umesh Parashram Aher

Umesh Parashram Aher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process For the Preparation of Highly Pure (E) N,N-Diethyl-2-Cyano-3-(3,4-Dihydroxy-5-Nitro Phenyl) Acrylamide (Entacapone)
    Publication number: 20080319226
    Abstract: A process for the preparation of highly pure (E)-N,N-diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylamide (Entacapone). It comprises condensing 3,4-dihydroxy-5-nitro benzaldehyde with N,N-diethyl cyano acetamide in an organic solvent in the presence of an organic base and an acid under reflux conditions followed by distilling off the solvent under vacuum and treating the residue with a lower aliphatic carboxylic acid at 40-8O0 C. The resulting residue is extracted with a chlorinated solvent and the solvent is distilled off under vacuum. The resulting residue is extracted with an organic solvent to obtain crude N,N-diethyl-2-cyano-3-3,4-dihydroxy-5-nitrophenyl)acrylamide. The crude product N,N-diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl) acrylamide formed is treated with a mixture of organic alcohol and organic acid in the molar ratio of the crude product to organic alcohol 1:5 to 15 and crude product to organic acid 1:1 to 3 under reflux conditions.
    Type: Application
    Filed: November 9, 2005
    Publication date: December 25, 2008
    Applicant: USV LIMITED
    Inventors: Venkatasubramanian Radhakrishnan Tarur, Dhananjay Govind Sathe, Nandu Baban Bhise, Avinash Venkatraman Naidu, Umesh Parashram Aher, Sachin Shivaji Patil
  • Pharmaceutical salt of (1-benzyl-4-[(5,6-dimethoxy-1-indanone)-2-yl] methyl piperidine (Donepezil)
    Patent number: 7439365
    Abstract: The present invention relates to the oxalate salt of 1-benzyl-4-[(5,6-dimethoxy-1-indanone)-2-yl]methyl piperidine, commonly known as Donepezil, and its method of preparation.
    Type: Grant
    Filed: June 29, 2004
    Date of Patent: October 21, 2008
    Assignee: USV, Ltd.
    Inventors: Venkatasubramanian Radhakrishnan Tarur, Dhananjay Govind Sathe, Avinash Venkatraman Naidu, Umesh Parashram Aher
  • Novel pharmaceutical salts of 1-benzyl-4-[ (5,6-dimethoxy-1-indanone)-2-yl] methyl piperidine ( Donepezil)
    Publication number: 20080076928
    Abstract: New salts of donepezil, and new polymorphic forms of donepezil and its salts, and methods to prepare both the amorphous form and various polymorphic forms of donepezil or its salts.
    Type: Application
    Filed: April 27, 2006
    Publication date: March 27, 2008
    Inventors: Venkatasubramanian Radhakrishnan Tarur, Dhanajay Govind Sathe, Avinash Vankatraman Naidu, Kamiesh Digamber Sawant, Tushar Anil Naik, Umesh Parashram Aher, Sachin Shivali Patil