Abstract: A method and composition for treating a host infected with hepatitis C comprising administering an effective hepatitis C treatment amount of a described 1?, 2? or 3?-modified nucleoside or a pharmaceutically acceptable salt or prodrug thereof, is provided.

Abstract: An apparatus for the local and/or remote rehabilitation and functional evaluation of the right and/or left hand of a user includes: a number of gym tools for the execution of hand exercises, each gym tool including a mechanical part, a sensor for the transformation of measured physical parameters into electrical signals; a user interface, configured to guide the user in the use of the gym tools, and providing feedbacks to the sequence of user actions; a first processing unit, configured to manage the apparatus functions, signal processing, storing and forwarding information on the measured physical parameters to at least one external device; a short-range communication module, configured to allow a real-time close-distance control of the apparatus; a wide-range communication module, configured to allow the connection to at least one long-distance tele-monitoring system.

Abstract: A method and composition for treating a host infected with hepatitis C comprising administering an effective hepatitis C treatment amount of a described 1?, 2? or 3?-modified nucleoside or a pharmaceutically acceptable salt or prodrug thereof, is provided.