Patents by Inventor Upma Sharma

Upma Sharma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • In-situ forming foams with outer layer
    Patent number: 9044580
    Abstract: Systems, methods and kits relating to in-situ forming polymer foams for the treatment of aneurysms or fluid filled spaces are disclosed. The systems include an insertable medical device and an in-situ forming foam of lava like materials with a fast forming outer skin and a slower hardening interior that is formed from a one-, two- or multi-part formulation. When used to treat an aneurysm, the foam is placed into contact with at least a portion of an exterior surface of the medical device and/or the tissue surface of the aneurysm.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: June 2, 2015
    Assignee: Arsenal Medical, Inc.
    Inventors: Toby Freyman, Joseph Lomakin, John Marini, Jennifer Mortensen, Adam Rago, Rany Busold, Upma Sharma, Gregory T. Zugates
  • Electrospinning process for fiber manufacture
    Patent number: 9034240
    Abstract: Devices and methods for high-throughput manufacture of concentrically layered nanoscale and microscale fibers by electrospinning are disclosed. The devices include a hollow tube having a lengthwise slit through which a core material can flow, and can be configured to permit introduction of sheath material at multiple sites of Taylor cone formation formation.
    Type: Grant
    Filed: February 4, 2013
    Date of Patent: May 19, 2015
    Assignee: Arsenal Medical, Inc.
    Inventors: Upma Sharma, Quynh Pham, John Marini
  • Foam and delivery system for treatment of postpartum hemorrhage
    Patent number: 8993831
    Abstract: Medical implants and methods useful in treating postpartum hemorrhage are disclosed. The implants, in some embodiments, comprise polyurethane foams having advantageous mechanical and other properties selected to promote hemostasis when brought in contact with an inner wall of a uterus. Methods of making and deploying such implants are also disclosed.
    Type: Grant
    Filed: June 28, 2012
    Date of Patent: March 31, 2015
    Assignee: Arsenal Medical, Inc.
    Inventors: Upma Sharma, Irina Gitlin, Parisa Zamiri, Toby Freyman, Rany Busold, Lee Core, Janet Chie Komatsu, Jennifer Mortensen
  • Medical implants
    Patent number: 8992601
    Abstract: Disclosed are self-expanding medical implants for placement within a lumen of a patient. The implants comprise a woven or non-woven structure having a substantially tubular configuration, and are designed to be low-profile such that they are deliverable with a small diameter catheter. The implants have a high recoverability and desired mechanical properties.
    Type: Grant
    Filed: February 13, 2013
    Date of Patent: March 31, 2015
    Assignee: 480 Biomedical, Inc.
    Inventors: Maria Palasis, Changcheng You, Daniel Concagh, Lee Core, Kicherl Ho, Upma Sharma, Gregory T. Zugates
  • Electrospinning process for manufacture of multi-layered structures
    Patent number: 8968626
    Abstract: Devices and methods for high-throughput manufacture of concentrically layered nanoscale and microscale fibers by electrospinning are disclosed. The devices include a hollow tube having a lengthwise slit through which a core material can flow, and can be configured to permit introduction of sheath material at multiple sites of Taylor cone formation.
    Type: Grant
    Filed: January 31, 2012
    Date of Patent: March 3, 2015
    Assignee: Arsenal Medical, Inc.
    Inventors: Quynh Pham, Upma Sharma, John Marini, Xuri Yan, Lee Core
  • PATTERNED SLIT FIXTURES AND SURFACES FOR HIGH THROUGHPUT SLIT-SURFACE ELECTROSPlNNING
    Publication number: 20150035181
    Abstract: The present invention relates generally to the field of electrospinning. In particular, the present invention relates to an electrospinning device that includes a slit-fixture defined by an elongate aperture disposed between opposing elements of an electrically conductive material. These elements include a variety of patterns/shapes that affect the flow of fluid through the aperture and the electrical field across the aperture.
    Type: Application
    Filed: August 1, 2014
    Publication date: February 5, 2015
    Inventors: Quynh Pham, Upma Sharma, Xuri Yan, John Marini
  • INTRA-ABDOMINAL PRESSURE TO PROMOTE HEMOSTASIS AND SURVIVAL
    Publication number: 20150012031
    Abstract: Systems, methods and kits for treating hemorrhages within cavities are provided. The methods utilize the application of a rapid spike of pressure to the closed cavity, followed by a steady state pressure or pressures.
    Type: Application
    Filed: August 8, 2014
    Publication date: January 8, 2015
    Inventors: Adam RAGO, John Marini, Gregory T. Zugates, Marc Helmick, Upma Sharma
  • Drug eluting medical implant
    Patent number: 8888840
    Abstract: Disclosed are self-expanding medical implants for placement within a lumen of a patient. The implants comprise a woven or non-woven structure having a substantially tubular configuration, and are designed to be low-profile such that they are deliverable with a small diameter catheter. The implants have a high recoverability and desired mechanical properties.
    Type: Grant
    Filed: April 16, 2013
    Date of Patent: November 18, 2014
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Maria Palasis, Changcheng You, Daniel Concagh, Lee Core, Kirchel Ho, Upma Sharma, Gregory T. Zugates
  • Foam-Based Medical Treatments
    Publication number: 20140316367
    Abstract: The present invention relates generally to systems and methods and systems for generating polymer foams within body cavities to locate and/or control bleeding. The present invention further relates to methods and systems for generating polymer foams within non-compressible wounds to control or stop bleeding. The present invention further relates to the use of foams and gels for medical and cosmetic purposes.
    Type: Application
    Filed: March 17, 2014
    Publication date: October 23, 2014
    Inventors: Gregory T. Zugates, Adam Rago, Toby Freyman, Upma Sharma, Rany Busold, John Caulkins, Parisa Zamiri, Jennifer Mortensen, Meghan McGill, Daniel K. Bonner
  • Delivery System for In Situ Forming Foams and Methods of Using The Same
    Publication number: 20140228745
    Abstract: Delivery systems for in situ forming foam formulations are provided. The devices may include various actuation mechanisms and may entrain air into fluid formulation components in a variety of ways, including mixing with air and the addition of compressed gas.
    Type: Application
    Filed: March 14, 2014
    Publication date: August 14, 2014
    Inventors: Upma Sharma, Rany Busold, Adam Rago, Gregory T. Zugates, Toby Freyman, Lisette Manrique Miller
  • DRUG LOADED FIBERS
    Publication number: 20140199364
    Abstract: Implants and methods for the delivery of a therapeutic agent to a target location within a patient's body are disclosed. The implants include a fiber comprising a polymeric material and having a diameter of up to about twenty microns, and a first therapeutic agent within the fiber. The therapeutic agent is substantially in particulate form. The implants are of a variety of configurations, such as individual fibers, yarns, ropes, tubes, and patches.
    Type: Application
    Filed: February 5, 2014
    Publication date: July 17, 2014
    Inventors: Maria Palasis, Upma Sharma, Quynh Pham, John Marini
  • MEDICAL IMPLANT
    Publication number: 20140121762
    Abstract: Disclosed is a self-expanding medical implant for placement within a lumen of a patient. The implant comprises a woven or non-woven structure having a substantially tubular configuration, and is designed to be low-profile such that it is deliverable with a small diameter catheter. The implant has a high recoverability and desired mechanical properties.
    Type: Application
    Filed: October 16, 2013
    Publication date: May 1, 2014
    Inventors: Maria Palasis, Changcheng You, Danny Concagh, Lee Core, Kicherl Ho, Upma Sharma, Gregory T. Zugates
  • SYSTEMS AND METHODS FOR FACILITATING THE GENERATION OF CORE-SHEATH TAYLOR CONES IN ELECTROSPINNING
    Publication number: 20140103583
    Abstract: Systems and methods for electrospinning of core-sheath fibers are provided. The systems and methods achieve optimization of a shear stress that exists at a fluid boundary between core and sheath polymer solutions, by varying certain parameters of an electrospinning apparatus and/or the solutions used therewith.
    Type: Application
    Filed: October 15, 2013
    Publication date: April 17, 2014
    Inventors: Quynh Pham, UPMA SHARMA, JOHN MARINI, XURI YAN, ROBERT MULLIGAN, TOBY FREYMAN
  • DRUG-ELUTING MEDICAL IMPLANTS
    Publication number: 20140100644
    Abstract: Disclosed are self-expanding medical implants for placement within a lumen of a patient. The implants comprise a woven or non-woven structure having a substantially tubular configuration, and are designed to be low-profile such that they are deliverable with a small diameter catheter. The implants have a high recoverability and desired mechanical properties.
    Type: Application
    Filed: December 11, 2013
    Publication date: April 10, 2014
    Inventors: Maria Palasis, Changcheng You, Danny Concagh, Lee Core, Kicherl Ho, Upma Sharma, Gregory T. Zugates
  • DRUG ELUTING MEDICAL IMPLANT
    Publication number: 20130317600
    Abstract: Disclosed are self-expanding medical implants for placement within a lumen of a patient. The implants comprise a woven or non-woven structure having a substantially tubular configuration, and are designed to be low-profile such that they are deliverable with a small diameter catheter. The implants have a high recoverability and desired mechanical properties.
    Type: Application
    Filed: April 16, 2013
    Publication date: November 28, 2013
    Inventors: Maria Palasis, Changcheng You, Danny Concagh, Lee Core, Kicherl Ho, Upma Sharma, Greg Zugates
  • In-situ Forming foams with outer layer
    Publication number: 20130317418
    Abstract: Systems, methods and kits relating to in-situ forming polymer foams for the treatment of aneurysms or fluid filled spaces are disclosed. The systems include an insertable medical device and an in-situ forming foam of lava like materials with a fast forming outer skin and a slower hardening interior that is formed from a one-, two- or multi-part formulation. When used to treat an aneurysm, the foam is placed into contact with at least a portion of an exterior surface of the medical device and/or the tissue surface of the aneurysm.
    Type: Application
    Filed: March 15, 2013
    Publication date: November 28, 2013
    Inventors: Toby Freyman, Joseph Lomakin, John Marini, Jennifer Mortensen, Adam Rago, Rany Busold, Upma Sharma, Gregory T. Zugates
  • ELECTROSPINNING PROCESS FOR FIBER MANUFACTURE
    Publication number: 20130313758
    Abstract: Devices and methods for high-throughput manufacture of concentrically layered nanoscale and microscale fibers by electrospinning are disclosed. The devices include a hollow tube having a lengthwise slit through which a core material can flow, and can be configured to permit introduction of sheath material at multiple sites of Taylor cone formation formation.
    Type: Application
    Filed: February 4, 2013
    Publication date: November 28, 2013
    Inventors: Upma Sharma, Quynh Pham, John Marini
  • Drug Eluting Medical Implant
    Publication number: 20130304177
    Abstract: Disclosed are self-expanding medical implants for placement within a lumen of a patient. The implants comprise a woven or non-woven structure having a substantially tubular configuration, and are designed to be low-profile such that they are deliverable with a small diameter catheter. The implants have a high recoverability and desired mechanical properties.
    Type: Application
    Filed: May 10, 2013
    Publication date: November 14, 2013
    Inventors: Maria Palasis, Changcheng You, Danny Concagh, Lee Core, Kicherl Ho, Upma Sharma, Gregory T. Zugates
  • Medical implant
    Patent number: 8540765
    Abstract: Disclosed is a self-expanding medical implant for placement within a lumen of a patient. The implant comprises a woven or non-woven structure having a substantially tubular configuration, and is designed to be low-profile such that it is deliverable with a small diameter catheter. The implant has a high recoverability and desired mechanical properties.
    Type: Grant
    Filed: February 9, 2012
    Date of Patent: September 24, 2013
    Assignee: 480 Biomedical, Inc.
    Inventors: Maria Palasis, Chang Cheng You, Daniel Concagh, Lee Core, Kicherl Ho, Upma Sharma, Greg Zugates
  • Electrospinning Process for Manufacture of Multi-Layered Structures
    Publication number: 20130241115
    Abstract: Devices and methods for high-throughput manufacture of concentrically layered nanoscale and microscale fibers by electrospinning are disclosed. The devices include a hollow tube having a lengthwise slit through which a core material can flow, and can be configured to permit introduction of sheath material at multiple sites of Taylor cone formation formation.
    Type: Application
    Filed: February 4, 2013
    Publication date: September 19, 2013
    Inventors: Upma Sharma, Quynh Pham, John Marini, Xuri Yan, Lee Core