Patents by Inventor Uwe Demelbauer

Uwe Demelbauer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of Mapping Glycans of Glycoproteins in Serum Samples
    Publication number: 20170205423
    Abstract: The present invention relates to a method for analyzing glycans of a recombinant glycoprotein in a liquid sample of a mammal. Specifically the method comprises a step of affinity purifying the recombinant glycoprotein from the sample, enzymatically releasing a glycan containing fragment from the immobilized glycoprotein, adding a reference standard containing isotopically labeled glycans, fluorescently label the glycans and analyzing the glycans using LC-MS. The present invention also relates to a method further comprising analyzing the glycans of the immobilized recombinant glycoprotein fragment, further comprising a pre-clearing step of the liquid sample, and releasing the glycans from the immobilized recombinant glycoprotein fragment.
    Type: Application
    Filed: July 17, 2015
    Publication date: July 20, 2017
    Applicant: Hexal AG
    Inventors: Fabian Higel, Andreas Seidl, Uwe Demelbauer