Patents by Inventor Uwe Reusch

Uwe Reusch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Single-chain antibody acting against 37 kda/67 kda laminin receptor as tools for the diagnosis and therapy of prion diseases and cancer, production and use thereof
    Publication number: 20070041977
    Abstract: Single-chain antibodies are described which specifically recognize both the 37 kDa precursor form of the laminin receptor (37 kDa LRP) and the 67 kDa high-affinity form of the laminin receptor (67 kDa LR), and pharmaceutical and diagnostic compositions which contain these single-chain antibodies.
    Type: Application
    Filed: October 8, 2004
    Publication date: February 22, 2007
    Inventors: Stefan Knackmuss, Clemence Rey, Peter Rottgen, Claudia Buttner, Uwe Reusch
  • Human cd3-specific antibody with immunosuppressive properties
    Publication number: 20060233787
    Abstract: Described are mono- and multivalent scFv-antibodies comprising the binding sites specific for human T cell marker CD3. These antibodies are strongly immunosuppressive and do not cause a significant release of cytokines. Furthermore, polynucleotides encoding said antibodies are described as well as vectors comprising said polynucleotides, host cells transformed therewith and their use in the production of said antibodies. Pharmaceutical compositions containing any of the above mentioned polynucleotides, antibodies or vectors are useful for immunotherapy, preferably against acute transplant rejections.
    Type: Application
    Filed: September 10, 2003
    Publication date: October 19, 2006
    Inventors: Fabrice Le Gall, Sergey Kipriyanov, Melvin Little, Uwe Reusch
  • Dimeric and multimeric antigen binding structure
    Publication number: 20050079170
    Abstract: The present invention relates to dimeric and multimeric antigen binding structures, expression vectors encoding said structures, and diagnostic, as well as therapeutic, uses of said structures. The antigen binding structures are preferably in the form of a Fv-antibody construct.
    Type: Application
    Filed: September 13, 2002
    Publication date: April 14, 2005
    Inventors: Fabrice Le Gall, Sergey Kipriyanov, Uwe Reusch, Gerhard Moldenhauer, Melvyn Little