Patents by Inventor Véronique Gomord
Véronique Gomord has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190160167Abstract: The present invention relates to a type I or II transmembrane fusion protein comprising, successively: a) optionally, a signal peptide; b) a protein or a peptide of interest; c) a coiled-coil domain; and d) a domain for anchoring in the plasma membrane, consisting of a transmembrane segment and a cytosolic segment. It also relates to the virus-like particles obtained with this fusion protein.Type: ApplicationFiled: July 28, 2017Publication date: May 30, 2019Inventors: Véronique GOMORD, Louis-Philippe VEZINA, Loïc FAYE, Virginie CATALA, Anne-Catherine FITCHETTE
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Publication number: 20180105827Abstract: A method for producing a recombinant protein in a plant, in particular a tobacco plant, preferably Nicotiana benthamiana, includes the following steps: a) culturing the plant aeroponically or hydroponically, preferably on mobile floats and under LED lighting; b) vacuum agroinfiltration of the plant obtained in a) by agrobacteria that include a DNA fragment coding for the recombinant protein; c) returning the plants to culture after step b), under the same conditions as for step a); and d) extracting and purifying the recombinant protein from the aerial portions of the plants produced in step c).Type: ApplicationFiled: November 21, 2017Publication date: April 19, 2018Inventors: Veronique GOMORD, Anne Catherine FITCHETTE, Loic FAYE
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Patent number: 9856489Abstract: A method for producing a recombinant protein in a plant, in particular a tobacco plant, preferably Nicotiana benthamiana, includes the following steps: a) culturing the plant aeroponically or hydroponically, preferably on mobile floats and under LED lighting; b) vacuum agroinfiltration of the plant obtained in a) by agrobacteria that include a DNA fragment coding for the recombinant protein; c) returning the plants to culturing after step b), under the same conditions as for step a); and d) extracting and purifying the recombinant protein from the aerial portions of the plants produced in step c).Type: GrantFiled: June 13, 2013Date of Patent: January 2, 2018Assignee: ANGANY GENETICSInventors: Veronique Gomord, Anne Catherine Fitchette, Loic Faye
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Publication number: 20170247714Abstract: A method of synthesizing sialic acid in plants, and plants capable of synthesizing sialic acid is provided. Furthermore, a method of producing sialylated protein in a plant is also provided. The method to synthesize sialic acid comprises providing a plant comprising a nucleotide sequence encoding N-acetyl neuraminic acid (Neu5Ac) synthase or Neu5Ac lyase, and expressing the nucleotide sequence thereby synthesizing sialic acid. The plant may also co-express a nucleotide sequence encoding one or more than one of an epimerase, a CMP-Neu5 Ac synthase, a CMP-Neu5Ac transporter and a sialyltransferase.Type: ApplicationFiled: March 30, 2017Publication date: August 31, 2017Applicants: Medicago, Inc., Centre National de la Recherche Scientifique, Universite De RouenInventors: Thomas PACCALET, Muriel BARDOR, Christophe RIHOUEY, Véronique GOMORD, Loïc FAYE, Patrice LEROUGE, Stéphanie AQUIN, Louis-Philippe VEZINA, Marc-André D'AOUST
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Publication number: 20170159037Abstract: A plant cell including a DNA molecule having at least one heterologous nucleotide sequence encoding a preproprotein of a pectate lyase chosen from Amb a 1, the alpha subunit of Amb a 1, the beta subunit of Amb a 1, and homologs of Amb a 1, functionally bound to a strong promoter.Type: ApplicationFiled: May 20, 2015Publication date: June 8, 2017Applicant: Angany GeneticsInventors: Veronique GOMORD, Anne-Catherine FITCHETTE, Virginie CATALA, Loic FAYE
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Patent number: 9657305Abstract: A method of synthesizing sialic acid in plants, and plants capable of synthesizing sialic acid is provided. Furthermore, a method of producing sialylated protein in a plant is also provided. The method to synthesize sialic acid comprises providing a plant comprising a nucleotide sequence encoding N-acetyl neuraminic acid (Neu5Ac) synthase or Neu5Ac lyase, and expressing the nucleotide sequence thereby synthesizing sialic acid. The plant may also co-express a nucleotide sequence encoding one or more than one of an epimerase, a CMP-Neu5Ac synthase, a CMP-Neu5Ac transporter and a sialyltransferase.Type: GrantFiled: November 4, 2015Date of Patent: May 23, 2017Assignees: Medicago Inc., Centre National de la Recherche Scientifique, Universite De RouenInventors: Thomas Paccalet, Muriel Bardor, Christophe Rihouey, Véronique Gomord, Loïc Faye, Patrice Lerouge, Stéphanie Aquin, Louis-Philippe Vezina, Marc-André D'Aoust
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Publication number: 20160145664Abstract: A method of synthesizing sialic acid in plants, and plants capable of synthesizing sialic acid is provided. Furthermore, a method of producing sialylated protein in a plant is also provided. The method to synthesize sialic acid comprises providing a plant comprising a nucleotide sequence encoding N-acetyl neuraminic acid (Neu5Ac) synthase or Neu5Ac lyase, and expressing the nucleotide sequence thereby synthesizing sialic acid. The plant may also co-express a nucleotide sequence encoding one or more than one of an epimerase, a CMP-Neu5Ac synthase, a CMP-Neu5Ac transporter and a sialyltransferase.Type: ApplicationFiled: November 4, 2015Publication date: May 26, 2016Applicants: Medicago Inc., Centre National de la Recherche Scientifique, Universite De RouenInventors: Thomas PACCALET, Muriel BARDOR, Christophe RIHOUEY, Véronique GOMORD, Loïc FAYE, Patrice LEROUGE, Stéphanie AQUIN, Louis-Philippe VEZINA, Marc-André D'AOUST
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Publication number: 20150361143Abstract: A method for producing a recombinant protein in a plant, in particular a tobacco plant, preferably Nicotiana benthamiana, includes the following steps: a) culturing the plant aeroponically or hydroponically, preferably on mobile floats and under LED lighting; b) vacuum agroinfiltration of the plant obtained in a) by agrobacteria that include a DNA fragment coding for the recombinant protein; c) returning the plants to culturing after step b), under the same conditions as for step a); and d) extracting and purifying the recombinant protein from the aerial portions of the plants produced in step c).Type: ApplicationFiled: June 13, 2013Publication date: December 17, 2015Applicant: ANGANY GENETICSInventors: Veronique GOMORD, Anne Catherine FITCHETTE, Loic FAYE
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Patent number: 9212372Abstract: A method of synthesizing sialic acid in plants, and plants capable of synthesizing sialic acid is provided. Furthermore, a method of producing sialylated protein in a plant is also provided. The method to synthesize sialic acid comprises providing a plant comprising a nucleotide sequence encoding N-acetyl neuraminic acid (Neu5Ac) synthase or Neu5Ac lyase, and expressing the nucleotide sequence thereby synthesizing sialic acid. The plant may also co-express a nucleotide sequence encoding one or more than one of an epimerase, a CMP-Neu5 Ac synthase, a CMP-Neu5Ac transporter and a sialyltransferase.Type: GrantFiled: February 9, 2007Date of Patent: December 15, 2015Assignees: Medicago Inc., Centre National de la Recherche Scientifique, Université De RouenInventors: Thomas Paccalet, Muriel Bardor, Christophe Rihouey, Véronique Gomord, Loïc Faye, Patrice Lerouge, Stéphanie Aquin, Louis-Philippe Vezina, Marc-André D'Aoust
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Publication number: 20110195452Abstract: The present invention provides new tools useful for controlling the post-translational modifications of recombinant polypeptides. These tools are particular signal peptides allowing the targeting of recombinant polypeptides during their synthesis in a host cell to specific sub-cellular compartments and a specific designing of said recombinant polypeptides within said sub-cellular compartments. These signal peptides are SEQ ID no 1 to SEQ ID no 31 disclosed herein.Type: ApplicationFiled: November 8, 2007Publication date: August 11, 2011Applicant: Centre National De La Recherche Scientific-CNRSInventors: Véronique Gomord, Claude Saint-Jore-Dupas, Aurelia Boulaflous, Marie-christine Kieffer-Meyer, Loïc Faye
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Publication number: 20110008837Abstract: A method for synthesizing a protein of interest with a modified N-glycosylation profile within a plant, a portion of a plant, or a plant cell is provided. The method comprises co-expressing within a plant a nucleotide sequence encoding a first nucleotide sequence encoding a hybrid protein (GNT1-GalT) comprising a CTS domain of N-acetylglucosaminyl transferase (GNT1) fused to a catalytic domain of beta-1,4galactosyltransferase (GalT), the first nucleotide sequence operatively linked with a first regulatory region that is active in the plant, and a second nucleotide sequence for encoding the protein of interest, the second nucleotide sequence operatively linked with a second regulatory region that is active in the plant. The first and second nucleotide sequences are co-expressed to synthesize a protein of interest comprising glycans with the modified N-glycosylation profile within the plant, the portion of the plant, or the plant cell.Type: ApplicationFiled: June 13, 2008Publication date: January 13, 2011Inventors: Marc-Andre D-Aoust, Louis-Philippe Vezina, Stephanie Aquin, Estelle Marquet-Blouin, Muriel Bardor, Veronique Gomord, Christophe Rihouey, Thomas Paccalet, Carole Burel, Loic Faye, Patrice Lerouge, Christophe Sourrouille
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Publication number: 20090312240Abstract: A method of synthesizing sialic acid in plants, and plants capable of synthesizing sialic acid is provided. Furthermore, a method of producing sialylated a protein in a plant is also provided. The method to synthesize sialic acid comprises providing a plant comprising a nucleotide sequence encoding N-acetyl neuraminic acid (Neu5Ac) synthase or Neu5Ac lyase, and expressing the nucleotide sequence thereby synthesizing sialic acid. The plant may also co-express a nucleotide sequence encoding one or more than one of an epimerase, a CMP-Neu5 Ac synthase, CMP-Neu5Ac transporter and a sialyltransferase.Type: ApplicationFiled: February 9, 2007Publication date: December 17, 2009Inventors: Thomas Paccalet, Muriel Bardor, Chirstophe Rihouey, Véronique Gomord, Loïc Faye, Patrice Lerouge, Stéphanie Aquin, Louis-Philippe Vezina, Marc-André D'Aoust
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Publication number: 20080166360Abstract: A purified nucleic acid molecule comprising a nucleotide sequence coding for allergen Dac g 5 having amino acid sequence SEQ ID NO. 2, a derivative or a fragment thereof.Type: ApplicationFiled: September 13, 2007Publication date: July 10, 2008Applicants: Seita Groupe Altadis, a French corporation, Stallergenes, a French corporationInventors: Ronald van Ree, Erica Van Oort, Caroline Bonneau, Loic Faye, Veronique Gomord
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Patent number: 7285650Abstract: A purified nucleic acid molecule comprising a nucleotide sequence coding for allergen Dac g5 having amino acid sequence SEQ ID NO. 2, a derivative or a fragment thereof.Type: GrantFiled: November 25, 2002Date of Patent: October 23, 2007Assignees: Seita Groupe Altadis, StallergenesInventors: Ronald Van Ree, Erica Van Oort, Caroline Bonneau, Loic Faye, Veronique Gomord
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Publication number: 20050177891Abstract: The invention concerns a novel plant glucosidase I and nucleic acids coding for said enzyme involved in N-glycosylation of proteins during translation. The invention also concerns means for detecting said protein and nucleic acids, such as antibodies or nucleotide probes and primers.Type: ApplicationFiled: April 25, 2001Publication date: August 11, 2005Inventors: Murielle Boisson, Veronique Gomord, Patrice LeRouge, Loic Faye, Michel Caboche, Loic Lepiniec
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Publication number: 20030147880Abstract: A purified nucleic acid molecule comprising a nucleotide sequence coding for allergen Dac g5 havinge amino acid sequence SEQ ID NO. 2, a derivative or a fragment thereof.Type: ApplicationFiled: November 25, 2002Publication date: August 7, 2003Applicant: Seita Groupe AltadisInventors: Ronald Van Ree, Erica Van Oort, Caroline Bonneau, Loic Faye, Veronique Gomord