Patents by Inventor Vaclav KREMEN
Vaclav KREMEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11980473Abstract: This specification discloses systems, methods, devices, and other techniques for determining the location of a seizure-generating region of the brain of a mammal.Type: GrantFiled: May 25, 2018Date of Patent: May 14, 2024Assignees: Mayo Foundation for Medical Education and Research, The Board of Trustees of the University of Illinois and St. Anne's University Hospital BrnoInventors: Brent M. Berry, Gary C. Sieck, Gregory A. Worrell, Benjamin H. Brinkmann, Yogatheesan Varatharajah, Vaclav Kremen, Ravishankar Krishnan Iyer, Zbigniew Kalbarczyk, Jan Cimbalnik
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Patent number: 11647962Abstract: A behavioral state of a brain is classified by automatically selecting one or more sensors based on the signals received from each sensor and one or more selection criteria using one or more processors, calculating at least one measured value from the signal(s) of the selected sensor(s), classifying the behavioral state as: (a) an awake state whenever the measured value(s) for the selected sensor(s) is lower than a first threshold value, (b) a sleep state (N2) whenever the measured value(s) for the selected sensor(s) is equal to or greater than the first threshold value and the measured value(s) is not greater than a second threshold value, or (c) a slow wave sleep state (N3) whenever the measured value(s) from the selected sensor(s) is greater than the first threshold value and the measured value(s) is greater than the second threshold value, and providing a notification of the classified behavioral state.Type: GrantFiled: January 8, 2019Date of Patent: May 16, 2023Assignee: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCHInventors: Vaclav Kremen, Brent M. Berry, Benjamin I. Brinkmann, Squire M. Stead, Gregory A. Worrell
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Patent number: 11337637Abstract: Systems, methods, devices, and techniques for analyzing and applying features of a T-wave derived from an electrocardiogram. A computing system can receive a set of data that characterizes an electrocardiogram of a patient. The system can analyze the set of data to identify a T-wave that occurs in the electrocardiogram. The system can determine values of one or more features of the T-wave and provide the information that identifies the values of the one or more features of the T-wave to a user.Type: GrantFiled: August 31, 2017Date of Patent: May 24, 2022Assignee: Mayo Foundation for Medical Education and ResearchInventors: Peter A. Noseworthy, Bo Qiang, Paul A. Friedman, Alan M. Sugrue, Vaclav Kremen, Bryan L. Striemer, Charles J. Bruce, Virend K. Somers, Kevin E. Bennet, Michael J. Ackerman, Samuel J. Asirvatham, John J. Dillon, Christopher V. DeSimone
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Publication number: 20210275080Abstract: Systems, methods, devices, and techniques for analyzing and applying features of a T-wave derived from an electrocardiogram. A computing system can receive a set of data that characterizes an electrocardiogram of a patient. The system can analyze the set of data to identify a T-wave that occurs in the electrocardiogram. The system can determine values of one or more features of the T-wave and provide the information that identifies the values of the one or more features of the T-wave to a user.Type: ApplicationFiled: August 31, 2017Publication date: September 9, 2021Applicant: Mayo Foundation for Medical Education and ResearchInventors: Peter A. Noseworthy, Bo Qiang, Paul A. Friedman, Alan M. Sugrue, Vaclav Kremen, Bryan L. Striemer, Charles J. Bruce, Virend K. Somers, Kevin E. Bennet, Michael J. Ackerman, Samuel J. Asirvatham, John J. Dillon, Christopher V. DeSimone
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Patent number: 10918292Abstract: Non-invasive systems can be used to estimate cardiac output and stroke volume. For example, this document provides cuff occlusion systems and methods for their use so that cardiac output and stroke volume can be estimated in a non-invasive fashion. In some implementations, a patient's brachial artery is occluded by an inflatable cuff device for a period of time. A heart rate and a plurality of blood pressure pulse wave measurement curves can be measured using the cuff device. The data collected can be used to calculate an estimate of the patient's cardiac output and stroke volume.Type: GrantFiled: July 18, 2017Date of Patent: February 16, 2021Assignee: Mayo Foundation for Medical Education and ResearchInventors: Pavol Sajgalik, Vaclav Kremen, Bruce D. Johnson
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Publication number: 20210031044Abstract: Electrical stimulation of the brain in the lateral temporal cortex has been discovered to enhance memory performance. Also, consistent patterns of pupil response have been discovered to exist across and within distinct phases during encoding and recall of word lists and it is known that these pupillary changes also correlate with intracranial electrophysiologic activity. This document also describes systems and methods for enhancing memory and/or cognitive performance using these features as input for the delivery of electrical stimulation to the lateral temporal cortex of the brain.Type: ApplicationFiled: March 19, 2019Publication date: February 4, 2021Inventors: Michal T. Kucewicz, Brent M. Berry, Gregory A. Worrell, Vaclav Kremen
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Publication number: 20200337645Abstract: A behavioral state of a brain is classified by automatically selecting one or more sensors based on the signals received from each sensor and one or more selection criteria using one or more processors, calculating at least one measured value from the signal(s) of the selected sensor(s), classifying the behavioral state as: (a) an awake state whenever the measured value(s) for the selected sensor(s) is lower than a first threshold value, (b) a sleep state (N2) whenever the measured value(s) for the selected sensor(s) is equal to or greater than the first threshold value and the measured value(s) is not greater than a second threshold value, or (c) a slow wave sleep state (N3) whenever the measured value(s) from the selected sensor(s) is greater than the first threshold value and the measured value(s) is greater than the second threshold value, and providing a notification of the classified behavioral state.Type: ApplicationFiled: January 8, 2019Publication date: October 29, 2020Inventors: Vaclav Kremen, Brent M. Berry, Benjamin I. Brinkmann, Squire M. Stead, Gregory A. Worrell
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Publication number: 20200178832Abstract: This specification discloses systems, methods, devices, and other techniques for determining the location of a seizure-generating region of the brain of a mammal.Type: ApplicationFiled: May 25, 2018Publication date: June 11, 2020Inventors: Brent M. Berry, Gary C. Sieck, Gregory A. Worrell, Benjamin H. Brinkmann, Yogatheesan Varatharajah, Vaclav Kremen, Ravishankar Krishnan Iyer, Zbigniew Kalbarczyk, Jan Cimbalnik
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Publication number: 20200022592Abstract: Non-invasive systems and techniques can be used to accurately measure blood pressures of patients being supported by continuous flow left ventricular assist devices. For example, this document describes cuff occlusion devices and methods for their use so that the blood pressure and pulsatility of patients with significantly reduced pulsatility as a result of continuous flow left ventricular assist device support can be accurately measured in a non-invasive fashion.Type: ApplicationFiled: January 9, 2018Publication date: January 23, 2020Applicant: Mayo Foundation for Medical Education and ResearchInventors: Pavol Sajgalik, Vaclav Kremen, Lyle D. Joyce, John A. Schirger, Bruce D. Johnson, Troy J. Cross, Vratislav Fabian
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Publication number: 20190167121Abstract: Non-invasive systems can be used to estimate cardiac output and stroke volume. For example, this document provides cuff occlusion systems and methods for their use so that cardiac output and stroke volume can be estimated in a non-invasive fashion. In some implementations, a patient's brachial artery is occluded by an inflatable cuff device for a period of time. A heart rate and a plurality of blood pressure pulse wave measurement curves can be measured using the cuff device. The data collected can be used to calculate an estimate of the patient's cardiac output and stroke volume.Type: ApplicationFiled: July 18, 2017Publication date: June 6, 2019Applicant: Mayo Foundation for Medical Education and ResearchInventors: Pavol Sajgalik, Vaclav Kremen, Bruce D. Johnson
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Patent number: 10251567Abstract: An apparatus for an accurate automated non-invasive measurement of blood pressure waveform using brachial (occlusion) cuff pressurized above systolic pressure and using differential pressure sensor. The methodology involves measurement in suprasystolic mode and in utilization and construction of the device followed by algorithms for processing and analysis of measured blood pressure pulse waves and assessment of hemodynamic parameters of human cardiovascular system. The device includes an electro-pump connected to the collar device, a differential pressure sensor, pressure senor A, pressure sensor B, valve, closing a valve and the air reservoir. The cuff is wrapped around a person's arm. The values of the instantaneous pressure in the pneumatic portion of the device are converted into an electric signal by the pressure sensor A, pressure sensor B and the differential pressure sensor.Type: GrantFiled: January 9, 2017Date of Patent: April 9, 2019Assignees: Czech Technical University in Prague, Faculty of Electrical Engineering, Czech Technical University in Prague, Czech Institute of Informatics, Robotics and CyberneticsInventors: Vratislav Fabian, Vaclav Kremen, Martin Dobias
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Publication number: 20170196468Abstract: An apparatus for an accurate automated non-invasive measurement of blood pressure waveform using brachial (occlusion) cuff pressurized above systolic pressure and using differential pressure sensor. The methodology involves measurement in suprasystolic mode and in utilization and construction of the device followed by algorithms for processing and analysis of measured blood pressure pulse waves and assessment of hemodynamic parameters of human cardiovascular system. The device includes an electro-pump connected to the collar device, a differential pressure sensor, pressure senor A, pressure sensor B, valve, closing a valve and the air reservoir. The cuff is wrapped around a person's arm. The values of the instantaneous pressure in the pneumatic portion of the device are converted into an electric signal by the pressure sensor A, pressure sensor B and the differential pressure sensor.Type: ApplicationFiled: January 9, 2017Publication date: July 13, 2017Applicants: CZECH TECHNICAL UNIVERSITY IN PRAGUE, FACULTY OF ELECTRICA ENGINEERING, CZECH TECHNICAL UNIVERSITY IN PRAGUE, CZECH INSTITUTE OF INFORMATICS, ROBOTICSInventors: Vratislav FABIAN, Vaclav KREMEN, Martin DOBIAS