Patents by Inventor Valentina Hoyos Velez

Valentina Hoyos Velez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MARROW INFILTRATING LYMPHOCYTES (MILS) AS A SOURCE OF T-CELLS FOR CHIMERIC ANTIGEN RECEPTOR (CAR) THEREAPY
    Publication number: 20230210990
    Abstract: In some embodiments, marrow-infiltrating lymphocytes (“MILs”) comprising a chimeric antigen receptor (“CAR”) are provided. In some aspects, the embodiments relate to a MIL obtained from bone marrow comprising a chimeric antigen receptor. In some aspects, the embodiments relate to a method for treating a condition in a subject, comprising administering to the subject a MIL comprising a CAR.
    Type: Application
    Filed: November 30, 2022
    Publication date: July 6, 2023
    Inventors: Ivan M. Borrello, Kimberly A. Noonan, Drew M. Pardoll, Valentina Hoyos Velez
  • MARROW INFILTRATING LYMPHOCYTES (MILS) AS A SOURCE OF T-CELLS FOR CHIMERIC ANTIGEN RECEPTOR (CAR) THEREAPY
    Publication number: 20230016031
    Abstract: In some embodiments, marrow-infiltrating lymphocytes (“MILs”) comprising a chimeric antigen receptor (“CAR”) are provided. In some aspects, the embodiments relate to a method for making a recombinant MIL, comprising obtaining bone marrow comprising MILs; and transfecting, transforming, or transducing the MILs with a nucleic acid encoding a chimeric antigen receptor. In some aspects, the embodiments relate to a method for treating a condition in a subject, comprising administering to the subject a MIL comprising a CAR.
    Type: Application
    Filed: September 15, 2022
    Publication date: January 19, 2023
    Inventors: Ivan M. Borrello, Kimberly A. Noonan, Drew M. Pardoll, Valentina Hoyos Velez
  • Marrow infiltrating lymphocytes (MILs) as a source of T-cells for chimeric antigen receptor (CAR) therapy
    Patent number: 11478548
    Abstract: In some embodiments, marrow-infiltrating lymphocytes (“MILs”) comprising a chimeric antigen receptor (“CAR”) are provided. In some aspects, the embodiments relate to a method for making a recombinant MIL, comprising obtaining bone marrow comprising MILs; and transfecting, transforming, or transducing the MILs with a nucleic acid encoding a chimeric antigen receptor. In some aspects, the embodiments relate to a method for treating a condition in a subject, comprising administering to the subject a MIL comprising a CAR.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: October 25, 2022
    Assignee: The Johns Hopkins University
    Inventors: Ivan M. Borrello, Kimberly A. Noonan, Drew M. Pardoll, Valentina Hoyos Velez