Patents by Inventor Valerie Castellani

Valerie Castellani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANIMAL MODEL FOR STUDYING CANCER IMMUNOTHERAPY
    Publication number: 20230146422
    Abstract: The invention relates to a chimeric gallinaceous bird embryo comprising both types of exogenous cells: a. At least one population of cancer cells, and b. At least one population of immune cells, wherein said exogenous cancer cells are present in at least one tissue of said embryo, and said exogenous immune cells are present in at least one tissue of said embryo and/or circulate in the blood vessels of said embryo.
    Type: Application
    Filed: April 21, 2021
    Publication date: May 11, 2023
    Inventors: Valérie CASTELLANI, Céline DELLOYE-BOURGEOIS, Clélia Costechareyre, Loraine Jarrosson
  • Animal study model for cancer
    Patent number: 11006620
    Abstract: The invention concerns a gallinacean embryo in which cancer cells have been grafted within the embryo tissue, characterised in that the embryo is at a developmental stage between the HH10 and HH25 stages at the time of the grafting, wherein said cancer cells are not neuroblastoma cells and said cells form tumors inside the embryo.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: May 18, 2021
    Assignees: UNIVERSITE CLAUDE BERNARD LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS
    Inventors: Valerie Castellani-Lincontang, Celine Delloye-Bourgeois
  • ANIMAL STUDY MODEL FOR CANCER
    Publication number: 20180368373
    Abstract: The invention concerns a gallinacean embryo in which cancer cells have been grafted within the embryo tissue, characterised in that the embryo is at a developmental stage between the HH10 and HH25 stages at the time of the grafting, wherein said cancer cells are not neuroblastoma cells and said cells form tumors inside the embryo.
    Type: Application
    Filed: December 15, 2016
    Publication date: December 27, 2018
    Applicants: Universite Claude Bernard Lyon 1, Centre National de la Recherche Scientifique
    Inventors: Valerie CASTELLANI-LINCONTANG, Celine DELLOYE-BOURGEOIS
  • ANIMAL MODEL FOR STUDYING NEUROBLASTOMAS
    Publication number: 20170156297
    Abstract: The present invention relates to a gallinaceous bird embryo into which human neuroblastoma cells have been grafted at the level of the neural crests. The invention also relates to a process for preparing such a gallinaceous bird embryo, and to a process for screening for therapeutic molecules intended for the treatment of a neuroblastoma tumor based on the use of this gallinaceous bird embryo.
    Type: Application
    Filed: July 7, 2015
    Publication date: June 8, 2017
    Inventors: Valérie CASTELLANI, Céline DELLOYE-BOURGEOIS
  • Peptides capable of inducing attraction to the axonal growth and their use for treating neurodegenerative diseases
    Publication number: 20060058504
    Abstract: The present invention is directed to peptides comprising the sequence ASNKL (SEQ ID No. 1), inducing attraction of the axonal growth in presence of the semaphorin (Sema3A), L1 and NP-1 proteins and their use for the manufacture of a drug for neuronal/axonal regeneration or for treating neurodegenerative diseases. The present invention also includes a method for identifying a compound able to bind the NP-1, a method for identifying a compound able to revert the repulsory effect of Sema3A on the axonal growth from a suited cell, or methods to screen for molecules capable of blocking Sema3A-induced endocytosis.
    Type: Application
    Filed: April 18, 2003
    Publication date: March 16, 2006
    Applicants: Centre National de la Recherche Scientific (CNRS), Universite De La Mediterranee (ALX-Marseille II)
    Inventors: Genevieve Rougon, Valerie Castellani