Patents by Inventor Valerie Hulmann-Cottier

Valerie Hulmann-Cottier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HUMANIZED IMMUNOBINDERS OF CELL-SURFACE ANTIGENS
    Publication number: 20190382498
    Abstract: The invention provides methods for identifying immunobinders, such as scFv antibodies, capable of specifically binding to cell surface antigens, and compositions identified according to said methods.
    Type: Application
    Filed: August 29, 2019
    Publication date: December 19, 2019
    Inventors: David Urech, Valerie Hulmann-Cottier, Leonardo Borras
  • METHODS FOR IDENTIFYING IMMUNOBINDERS OF CELL-SURFACE ANTIGENS
    Publication number: 20180142028
    Abstract: The invention provides methods for identifying immunobinders, such as scFv antibodies, capable of specifically binding to cell surface antigens, and compositions identified according to said methods.
    Type: Application
    Filed: January 17, 2018
    Publication date: May 24, 2018
    Inventors: David Urech, Valerie Hulmann-Cottier
  • Humanized immunobinders of cell-surface antigens
    Patent number: 9908940
    Abstract: The invention provides methods for identifying immunobinders, such as scFv antibodies, capable of specifically binding to cell surface antigens, and compositions identified according to said methods.
    Type: Grant
    Filed: November 20, 2015
    Date of Patent: March 6, 2018
    Assignee: Esbatech, An Alcon Biomedical Research Unit LLC
    Inventors: David Urech, Valerie Hulmann-Cottier
  • METHODS FOR IDENTIFYING IMMUNOBINDERS OF CELL-SURFACE ANTIGENS
    Publication number: 20160152716
    Abstract: The invention provides methods for identifying immunobinders, such as scFv antibodies, capable of specifically binding to cell surface antigens, and compositions identified according to said methods.
    Type: Application
    Filed: November 20, 2015
    Publication date: June 2, 2016
    Inventors: David Urech, Valerie Hulmann-Cottier
  • Methods for producing immunobinders of cell-surface antigens
    Patent number: 9221905
    Abstract: The invention provides methods for identifying immunobinders, such as scFv antibodies, capable of specifically binding to cell surface antigens, and compositions identified according to said methods.
    Type: Grant
    Filed: May 8, 2014
    Date of Patent: December 29, 2015
    Assignee: ESBATech, an Alcon Biomedical Research Unit LLC
    Inventors: David Urech, Valerie Hulmann-Cottier
  • METHODS FOR IDENTIFYING IMMUNOBINDERS OF CELL-SURFACE ANTIGENS
    Publication number: 20150024432
    Abstract: The invention provides methods for identifying immunobinders, such as scFv antibodies, capable of specifically binding to cell surface antigens, and compositions identified according to said methods.
    Type: Application
    Filed: May 8, 2014
    Publication date: January 22, 2015
    Applicant: ESBATech, an Alcon Biomedical Research Unit LLC
    Inventors: David Urech, Valerie Hulmann-Cottier
  • METHODS AND COMPOSITIONS FOR ENHANCED DELIVERY OF MACROMOLECULES
    Publication number: 20140212421
    Abstract: The invention provides compositions and methods that enhance the delivery of large macromolecules (i.e., greater than 10 kDa), such as antigen-binding polypeptides, across tight junctions. Such methods and compositions are particularly useful for delivering therapeutic antigen-binding polypeptides to the CNS, via intranasal administration, for the treatment of neurological disorders.
    Type: Application
    Filed: February 26, 2014
    Publication date: July 31, 2014
    Applicant: ESBATech, an Alcon Biomedical Research Unit LLC
    Inventors: Valerie Hulmann-Cottier, David Urech, Esther Furrer
  • Methods and compositions for enhanced delivery of macromolecules
    Patent number: 8697074
    Abstract: The invention provides compositions and methods that enhance the delivery of large macromolecules (i.e., greater than 10 kDa), such as antigen-binding polypeptides, across tight junctions. Such methods and compositions are particularly useful for delivering therapeutic antigen-binding polypeptides to the CNS, via intranasal administration, for the treatment of neurological disorders.
    Type: Grant
    Filed: July 10, 2009
    Date of Patent: April 15, 2014
    Assignee: ESBATech, an Alcon Biomedical Research Unit LLC
    Inventors: Valerie Hulmann-Cottier, David Urech, Esther Furrer
  • Methods for identifying B-clones which bind cell-surface antigens
    Patent number: 8465937
    Abstract: The invention provides methods for identifying immunobinders, such as scFv antibodies, capable of specifically binding to cell surface antigens, and compositions identified according to said methods.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: June 18, 2013
    Assignee: ESBATech, an Alcon Biomedical Research Unit, LLC
    Inventors: David Urech, Valerie Hulmann-Cottier
  • METHODS FOR IDENTIFYING IMMUNOBINDERS OF CELL-SURFACE ANTIGENS
    Publication number: 20130090456
    Abstract: The invention provides methods for identifying immunobinders, such as scFv antibodies, capable of specifically binding to cell surface antigens, and compositions identified according to said methods.
    Type: Application
    Filed: September 14, 2012
    Publication date: April 11, 2013
    Applicant: ESBATECH, AN ALCON BIOMEDICAL RESEARCH UNIT LLC
    Inventors: David Urech, Valerie Hulmann-Cottier
  • METHODS FOR IDENTIFYING IMMUNOBINDERS OF CELL-SURFACE ANTIGENS
    Publication number: 20120288878
    Abstract: The invention provides methods for identifying immunobinders, such as scFv antibodies, capable of specifically binding to cell surface antigens, and compositions identified according to said methods.
    Type: Application
    Filed: June 22, 2012
    Publication date: November 15, 2012
    Applicant: ESBATECH, AN ALCON BIOMEDICAL RESEARCH UNIT LLC
    Inventors: David Urech, Valerie Hulmann-Cottier
  • Methods for identifying immunobinders of cell-surface antigens
    Patent number: 8227199
    Abstract: The invention provides methods for identifying immunobinders, such as scFv antibodies, capable of specifically binding to cell surface antigens, and compositions identified according to said methods.
    Type: Grant
    Filed: February 23, 2010
    Date of Patent: July 24, 2012
    Assignee: ESBATech, an Alcon Biomedical Research Unit, LLC
    Inventors: David Urech, Valerie Hulmann-Cottier
  • METHODS AND COMPOSITIONS FOR ENHANCED DELIVERY OF MACROMOLECULES
    Publication number: 20110135644
    Abstract: The invention provides compositions and methods that enhance the delivery of large macromolecules (i.e., greater than 10 kDa), such as antigen-binding polypeptides, across tight junctions. Such methods and compositions are particularly useful for delivering therapeutic antigen-binding polypeptides to the CNS, via intranasal administration, for the treatment of neurological disorders.
    Type: Application
    Filed: July 10, 2009
    Publication date: June 9, 2011
    Applicant: ESBATECH, AN ALCON BIOMEDICAL RESEARCH UNIT LLC
    Inventors: Valerie Hulmann-Cottier, David Urech, Esther Furrer
  • METHODS FOR IDENTIFYING IMMUNOBINDERS OF CELL-SURFACE ANTIGENS
    Publication number: 20100216170
    Abstract: The invention provides methods for identifying immunobinders, such as scFv antibodies, capable of specifically binding to cell surface antigens, and compositions identified according to said methods.
    Type: Application
    Filed: February 23, 2010
    Publication date: August 26, 2010
    Applicant: ESBATECH, AN ALCON BIOMEDICAL RESEARCH UNIT GMBH
    Inventors: David Urech, Valerie Hulmann-Cottier