Patents by Inventor Valeriy Metelev

Valeriy Metelev has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phosphoramidite nucleoside analogs
    Patent number: 8084589
    Abstract: Described are phosphoramidite nucleoside analog monomers, precursors thereof, and oligonucleotides including one or more of the monomers. The monomers can be used during automated synthesis of oligonucleotide derivatives, and allow for incorporation of one or several reporter groups, organic molecules, bio-molecules, small molecules or other chemical groups at the internucleoside phosphotriesters. Oligonucleotides including the monomers have a number of uses in therapeutic, diagnostic, and research applications.
    Type: Grant
    Filed: August 29, 2008
    Date of Patent: December 27, 2011
    Assignees: University of Massachusetts, The General Hospital Corporation Massachusetts
    Inventors: Alexei Bogdanov, Valeriy Metelev, David Tabatadze, Paul Zamecnik
  • PHOSPHORAMIDITE NUCLEOSIDE ANALOGS
    Publication number: 20090136940
    Abstract: Described are phosphoramidite nucleoside analog monomers, precursors thereof, and oligonucleotides including one or more of the monomers. The monomers can be used during automated synthesis of oligonucleotide derivatives, and allow for incorporation of one or several reporter groups, organic molecules, bio-molecules, small molecules or other chemical groups at the internucleoside phosphotriesters. Oligonucleotides including the monomers have a number of uses in therapeutic, diagnostic, and research applications.
    Type: Application
    Filed: August 29, 2008
    Publication date: May 28, 2009
    Applicants: University of Massachusetts, Massachusetts General Hospital
    Inventors: Alexei Bogdanov, Valeriy Metelev, David Tabatadze, Paul Zamecnik