Patents by Inventor Vanessa Sperandio

Vanessa Sperandio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF USING CANNABINOIDS FOR INHIBITING INDUCTION OF VIRULENCE IN ENTERIC PATHOGENS
    Publication number: 20210330603
    Abstract: Methods of treating a subject having a gram negative bacterial infection by administering a cannabinoid such as 2-AG,CBD, the MgI inhibitor JZL184, or arachidonic acid to the subject are provided. Methods of prophylactically treating a subject at risk of developing a gram negative bacterial infection and for reducing the bacterial virulence in an infected subject are also provided.
    Type: Application
    Filed: February 24, 2021
    Publication date: October 28, 2021
    Inventors: Jay Mellies, Vanessa Sperandio
  • Methods for modulating bacterial virulence and related compounds
    Patent number: 9604946
    Abstract: The present invention relates to compounds and methods for the treatment of bacterial infections. The compounds and methods involve the disruption of the QseC signaling pathway which modulates the virulence of some bacteria. This methodology for treatment of bacterial infections reduces evolutionary pressure to develop resistance because the bacteria are not killed in the process.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: March 28, 2017
    Assignee: The Board of Regents of the University of Texas System
    Inventors: Vanessa Sperandio, John R. Falck
  • Methods for Modulating Bacterial Virulence and Related Compounds
    Publication number: 20140275189
    Abstract: The present invention relates to compounds and methods for the treatment of bacterial infections. The compounds and methods involve the disruption of the QseC signaling pathway which modulates the virulence of some bacteria. This methodology for treatment of bacterial infections reduces evolutionary pressure to develop resistance because the bacteria are not killed in the process.
    Type: Application
    Filed: March 10, 2014
    Publication date: September 18, 2014
    Applicant: The Board of Regents of the University of Texas System
    Inventors: Vanessa Sperandio, John R. Falck
  • Methods of inhibiting bacterial virulence and compounds relating thereto
    Patent number: 8252841
    Abstract: The present invention relates to compounds and methods for the treatment of bacterial infections. Because their mechanism of action does not involve killing of bacteria or inhibiting their growth, the potential for these compounds to induce drug resistance in bacteria is minimized. Through inhibiting bacterial virulence, the present invention provides a novel means of treating bacterial infections.
    Type: Grant
    Filed: October 20, 2008
    Date of Patent: August 28, 2012
    Assignees: The Board of Regents of the University of Texas System, OMM Scientific Inc.
    Inventors: Vanessa Sperandio, John R. Falck, Donald R. Stewart
  • Methods of Inhibiting Bacterial Virulence and Compounds Relating Thereto
    Publication number: 20100048573
    Abstract: The present invention relates to compounds and methods for the treatment of bacterial infections. Because their mechanism of action does not involve killing of bacteria or inhibiting their growth, the potential for these compounds to induce drug resistance in bacteria is minimized. Through inhibiting bacterial virulence, the present invention provides a novel means of treating bacterial infections.
    Type: Application
    Filed: October 20, 2008
    Publication date: February 25, 2010
    Inventors: Vanessa Sperandio, John R. Falck, Donald R. Stewart