Patents by Inventor Vannary TIENG CAULET

Vannary TIENG CAULET has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ELIMINATION OF PROLIFERATING CELLS FROM STEM CELL-DERIVED GRAFTS
    Publication number: 20230257774
    Abstract: Provided herein are methods and compositions for a suicide gene approach comprising an expression vector comprising a cell cycle-dependent promoter driving the expression of a suicide gene. Also provided herein are methods to render proliferative cells sensitive to a prodrug after transplantation but avoids expression of the suicide gene in post-mitotic cells, such as neurons.
    Type: Application
    Filed: November 30, 2022
    Publication date: August 17, 2023
    Applicant: Research Development Foundation
    Inventors: Karl-Heinz KRAUSE, Michel DUBOIS-DAUPHIN, Vannary TIENG CAULET
  • Elimination of proliferating cells from stem cell-derived grafts
    Patent number: 11542524
    Abstract: Provided herein are methods and compositions for a suicide gene approach comprising an expression vector comprising a cell cycle-dependent promoter driving the expression of a suicide gene. Also provided herein are methods to render proliferative cells sensitive to a prodrug after transplantation but avoids expression of the suicide gene in post-mitotic cells, such as neurons.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: January 3, 2023
    Assignee: Research Development Foundation
    Inventors: Karl-Heinz Krause, Michel Dubois-Dauphin, Vannary Tieng Caulet
  • ELIMINATION OF PROLIFERATING CELLS FROM STEM CELL-DERIVED GRAFTS
    Publication number: 20220267801
    Abstract: Provided herein are methods and compositions for a suicide gene approach comprising an expression vector comprising a cell cycle-dependent promoter driving the expression of a suicide gene. Also provided herein are methods to render proliferative cells sensitive to a prodrug after transplantation but avoids expression of the suicide gene in post-mitotic cells, such as neurons.
    Type: Application
    Filed: May 11, 2022
    Publication date: August 25, 2022
    Applicant: Research Development Foundation
    Inventors: Karl-Heinz KRAUSE, Michel DUBOIS-DAUPHIN, Vannary TIENG CAULET
  • ELIMINATION OF PROLIFERATING CELLS FROM STEM CELL-DERIVED GRAFTS
    Publication number: 20190160113
    Abstract: Provided herein are methods and compositions for a suicide gene approach comprising an expression vector comprising a cell cycle-dependent promoter driving the expression of a suicide gene. Also provided herein are methods to render proliferative cells sensitive to a prodrug after transplantation but avoids expression of the suicide gene in post-mitotic cells, such as neurons.
    Type: Application
    Filed: November 29, 2018
    Publication date: May 30, 2019
    Inventors: Karl-Heinz KRAUSE, Michel DUBOIS-DAUPHIN, Vannary TIENG CAULET
  • ELIMINATION OF PROLIFERATING CELLS FROM STEM CELL-DERIVED GRAFTS
    Publication number: 20180030478
    Abstract: Provided herein are methods and compositions for a suicide gene approach comprising an expression vector comprising a cell cycle-dependent promoter driving the expression of a suicide gene. Also provided herein are methods to render proliferative cells sensitive to a prodrug after transplantation but avoids expression of the suicide gene in post-mitotic cells, such as neurons.
    Type: Application
    Filed: June 30, 2017
    Publication date: February 1, 2018
    Inventors: Karl-Heinz KRAUSE, Michel DUBOIS-DAUPHIN, Vannary TIENG CAULET