Patents by Inventor Vasile V. Cosofret

Vasile V. Cosofret has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6896793
    Abstract: The invention relates to a durable and reliable miniature liquid junction reference electrode for use with at least one electrode (e.g., an electrochemical sensor cartridge) for measuring certain characteristics of a fluid sample such as blood or other body fluid.
    Type: Grant
    Filed: March 7, 2002
    Date of Patent: May 24, 2005
    Assignee: Instrumentation Laboratory Company
    Inventors: Miklos Erdosy, Vasile V. Cosofret
  • Publication number: 20040256227
    Abstract: An electrochemical sensor for detecting urea in a sample includes a composite membrane that includes an enzymatic layer and an outer diffusional layer. The outer diffusional layer is disposed between the enzymatic layer and the analytical sample, preventing direct contact between the enzymatic layer and the analytical sample.
    Type: Application
    Filed: June 9, 2004
    Publication date: December 23, 2004
    Inventors: Jungwon Shin, Vasile V. Cosofret
  • Publication number: 20040154933
    Abstract: A method for reducing interference caused by contaminants on the detection and/or measurement of an analyte in a biological sample includes providing a chemical sensor that contains carboxylated polyvinyl chloride (PVC—COOH) as a polymer component of the sensor's polymeric membrane. A biological sample containing the analyte of interest and a contaminant is placed in contact with the chemical sensor that includes PVC—COOH as a polymer component of the sensor's polymeric membrane. The analyte of interest in the biological sample is then measured and/or detected by the chemical sensor without interference by the contaminant.
    Type: Application
    Filed: February 11, 2003
    Publication date: August 12, 2004
    Applicant: Instrumentation Laboratory Company
    Inventor: Vasile V. Cosofret
  • Publication number: 20030029722
    Abstract: The invention relates to a durable and reliable miniature liquid junction reference electrode for use with at least one electrode (e.g., an electrochemical sensor cartridge) for measuring certain characteristics of a fluid sample such as blood or other body fluid.
    Type: Application
    Filed: March 7, 2002
    Publication date: February 13, 2003
    Applicant: Instrumentation Laboratory Company
    Inventors: Miklos Erdosy, Vasile V. Cosofret
  • Patent number: 6123820
    Abstract: Sensor cartridges include a fluid constituent-selective sensor membrane in direct sealing contact with a face of a flow-through sample cell in surrounding relationship to a sensor port. The sensor membrane has sufficiently large surface area so as to entirely cover the sensor port and establish an annular region in surrounding relationship thereto. It is this annular region which is in direct contact with a corresponding region of the sample cell face so as to provide self-sealing capabilities. The sensor cartridge most preferably includes a flow-through sample cell having a zig-zag or serpentine flow channel so as to provide a series of sensor ports on both of the opposed cell faces. The faces of the sample cell are most preferably provided with recessed regions which define a series of land surfaces each of which surrounds a respective one of the sensor ports.
    Type: Grant
    Filed: June 5, 1998
    Date of Patent: September 26, 2000
    Assignees: Grupo Ch-Werfen, S.A., Duke University, The University of North Carolina, Case Western Reserve University
    Inventors: Carolyn Bergkuist, Richard P. Buck, Vasile V. Cosofret, Chung-Chuin Liu, Richard A. Lucic, John P. Moriarty, Michael R. Neuman, Richard M. Bucchianeri
  • Patent number: 5403895
    Abstract: Disclosed are a copolymer composition comprising a substituted halo-polymer wherein from about 0.01% to about by weight of the halo moieties therein are replaced with piperazine, and a flexible plastic film made from the copolymer. The copolymer is inherently conductive.
    Type: Grant
    Filed: April 7, 1993
    Date of Patent: April 4, 1995
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Robert P. Kusy, Vasile V. Cosofret, John Q. Whitley, Erno Lindner, Richard P. Buck