Patents by Inventor Vasiliy A. Portnoy

Vasiliy A. Portnoy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • metabolic engineering oxygen independent platform strains and methods of use thereof
    Patent number: 9080178
    Abstract: The invention provides transgenic Escherichia coli cells comprising a mutation in cydAB gene, and/or cyoABCD gene, and/or cbdAB gene, and/or ygiN gene, wherein the mutation reduces (preferably, but not necessarily, by 100%) the cytochrome oxydase activity of a protein encoded by cydAB gene, and/or cyoABCD gene, and/or cbdAB gene, and/or ygiN gene. In a preferred embodiment, the mutation is a deletion of the cydAB gene, cyoABCD gene, and cbdAB gene. In another embodiment, the mutation is a deletion of the cydAB gene, cyoABCD gene, cbdAB gene, and ygiN gene.
    Type: Grant
    Filed: June 22, 2011
    Date of Patent: July 14, 2015
    Assignee: The Regents Of The University Of California
    Inventors: Bernhard Palsson, Vasiliy A. Portnoy
  • ESCHERICHIA COLI METABOLIC ENGINEERING OXYGEN INDEPENDENT PLATFORM STRAINS AND METHODS OF USE THEREOF
    Publication number: 20120064581
    Abstract: The invention provides transgenic Escherichia coli cells comprising a mutation in cydAB gene, and/or cyoABCD gene, and/or cbdAB gene, and/or ygiN gene, wherein the mutation reduces (preferably, but not necessarily, by 100%) the cytochrome oxydase activity of a protein encoded by cydAB gene, and/or cyoABCD gene, and/or cbdAB gene, and/or ygiN gene. In a preferred embodiment, the mutation is a deletion of the cydAB gene, cyoABCD gene, and cbdAB gene. In another embodiment, the mutation is a deletion of the cydAB gene, cyoABCD gene, cbdAB gene, and ygiN gene.
    Type: Application
    Filed: June 22, 2011
    Publication date: March 15, 2012
    Inventors: Bernhard Palsson, Vasiliy A. Portnoy