Patents by Inventor Vaughn Ostland

Vaughn Ostland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11142572
    Abstract: Disclosed herein are antibodies specific for erythroferrone and assays comprising the antibodies. Also disclosed are methods for using the assays for the diagnosis or monitoring of disease.
    Type: Grant
    Filed: February 21, 2020
    Date of Patent: October 12, 2021
    Assignee: INTRINSIC LIFESCIENCES LLC
    Inventors: Mark Westerman, Huiling Han, Vaughn Ostland
  • Publication number: 20200300873
    Abstract: The present invention is generally related to kits for measuring a level of hepcidin in a biological sample in an in vitro assay compared to a standard control. The kits may further include instructions for use, a label for use, or both. The kits may be used to identify an individual having a disease or disorder associated with an elevated level of hepcidin, a reduced level of hepcidin, an elevated level of iron, a reduced level of iron, or a combination thereof.
    Type: Application
    Filed: November 21, 2016
    Publication date: September 24, 2020
    Inventors: Mark Westerman, Patrick Gutschow, Vaughn Ostland
  • Publication number: 20200231668
    Abstract: Disclosed herein are antibodies specific for erythroferrone and assays comprising the antibodies. Also disclosed are methods for using the assays for the diagnosis or monitoring of disease.
    Type: Application
    Filed: February 21, 2020
    Publication date: July 23, 2020
    Inventors: Mark Westerman, Huiling Han, Vaughn Ostland
  • Patent number: 10604567
    Abstract: Disclosed herein are antibodies specific for erythroferrone and assays comprising the antibodies. Also disclosed are methods for using the assays for the diagnosis or monitoring of disease.
    Type: Grant
    Filed: March 13, 2018
    Date of Patent: March 31, 2020
    Assignee: INTRINSIC LIFESCIENCES LLC
    Inventors: Mark Westerman, Huiling Han, Vaughn Ostland
  • Patent number: 10239941
    Abstract: The present application relates to antibodies that specifically bind to hepcidin and methods of using the antibodies. Another aspect relates to antibodies which bind hepcidin and regulate iron homeostasis. Another aspect relates to the use of humanized antibodies which bind hepcidin for the treatment of a disease or condition associated with hepcidin.
    Type: Grant
    Filed: August 31, 2017
    Date of Patent: March 26, 2019
    Assignee: Intrinsic Lifesciences LLC
    Inventors: Mark Westerman, Vaughn Ostland, Huiling Han, Patrick Gutschow, Keith Westerman, Gordana Olbina
  • Publication number: 20180258168
    Abstract: Disclosed herein are antibodies specific for erythroferrone and assays comprising the antibodies. Also disclosed are methods for using the assays for the diagnosis or monitoring of disease.
    Type: Application
    Filed: March 13, 2018
    Publication date: September 13, 2018
    Inventors: Mark Westerman, Huiling Han, Vaughn Ostland
  • Publication number: 20180057586
    Abstract: The present application relates to antibodies that specifically bind to hepcidin and methods of using the antibodies. Another aspect relates to antibodies which bind hepcidin and regulate iron homeostasis. Another aspect relates to the use of humanized antibodies which bind hepcidin for the treatment of a disease or condition associated with hepcidin.
    Type: Application
    Filed: August 31, 2017
    Publication date: March 1, 2018
    Inventors: Mark Westerman, Vaughn Ostland, Huiling Han, Patrick Gutschow, Keith Westerman, Gordana Olbina
  • Patent number: 9803011
    Abstract: The present application relates to antibodies that specifically bind to hepcidin and methods of using the antibodies. Another aspect relates to antibodies which bind hepcidin and regulate iron homeostasis. Another aspect relates to the use of humanized antibodies which bind hepcidin for the treatment of a disease or condition associated with hepcidin.
    Type: Grant
    Filed: April 11, 2017
    Date of Patent: October 31, 2017
    Assignee: Intrinsic Lifesciences LLC
    Inventors: Mark Westerman, Vaughn Ostland, Huiling Han, Patrick Gutschow, Keith Westerman, Gordana Olbina
  • Publication number: 20170283495
    Abstract: The present application relates to antibodies that specifically bind to hepcidin and methods of using the antibodies. Another aspect relates to antibodies which bind hepcidin and regulate iron homeostasis. Another aspect relates to the use of humanized antibodies which bind hepcidin for the treatment of a disease or condition associated with hepcidin.
    Type: Application
    Filed: April 11, 2017
    Publication date: October 5, 2017
    Inventors: Mark WESTERMAN, Vaughn OSTLAND, Huiling HAN, Patrick GUTSCHOW, Keith WESTERMAN, Gordana OLBINA
  • Patent number: 9657098
    Abstract: The present application relates to antibodies that specifically bind to hepcidin and methods of using the antibodies. Another aspect relates to antibodies which bind hepcidin and regulate iron homeostasis. Another aspect relates to the use of humanized antibodies which bind hepcidin for the treatment of a disease or condition associated with hepcidin.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: May 23, 2017
    Assignee: INTRINSIC LIFESCIENCES, LLC
    Inventors: Mark Westerman, Vaughn Ostland, Huiling Han, Patrick Gutschow, Keith Westerman, Gordana Olbina
  • Publication number: 20160017032
    Abstract: The present application relates to antibodies that specifically bind to hepcidin and methods of using the antibodies. Another aspect relates to antibodies which bind hepcidin and regulate iron homeostasis. Another aspect relates to the use of humanized antibodies which bind hepcidin for the treatment of a disease or condition associated with hepcidin.
    Type: Application
    Filed: March 13, 2014
    Publication date: January 21, 2016
    Inventors: Mark Westerman, Vaughn Ostland, Huiling Han, Patrick Gutschow, Keith Westerman, Gordana Olbina
  • Publication number: 20060019339
    Abstract: The present invention concerns a method for the oxidative refolding of a hepcidin polypeptide to a form that is mature, bioactive and folded as in the native configuration and molecular mass; a method for measuring the level of native, bioactive hepcidin in a vertebrate animal; a method for measuring the level of hepcidin gene expression in a vertebrate animal; and a method for regulating the production of native, bioactive hepcidin in a vertebrate animal in vivo. The present invention also concerns an antibody or fragment thereof that specifically binds to a continuous, discontinuous, and/or conformational epitope of a mature and bioactive hepcidin folded as in the native configuration; and a pharmaceutical composition that includes the antibody or a hepcidin polypeptide and that provides antimicrobial, agonistic, or antagonistic activities in vivo in a vertebrate animal.
    Type: Application
    Filed: April 28, 2005
    Publication date: January 26, 2006
    Inventors: Xavier Lauth, Mark Westerman, Vaughn Ostland, Jason Stannard, Michael Pennington