Patents by Inventor Venkat Rami Reddy Macherla
Venkat Rami Reddy Macherla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220227808Abstract: Provided are cyclic peptide analogs, conjugates comprising such compounds, and pharmaceutical compositions comprising such compounds and conjugates, and methods of treating cancer with such compounds and conjugates.Type: ApplicationFiled: December 22, 2021Publication date: July 21, 2022Inventors: Ippei USUI, Bryan Junn LEE, Steven Bruce COHEN, Venkat Rami Reddy MACHERLA, Jacob Neal BEVERAGE, Chung-Mao PAN, Farhana BARMARE, Eduardo ESQUENAZI
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Patent number: 11254705Abstract: Provided are cyclic peptide analogs, conjugates comprising such compounds, and pharmaceutical compositions comprising such compounds and conjugates, and methods of treating cancer with such compounds and conjugates.Type: GrantFiled: August 31, 2017Date of Patent: February 22, 2022Assignee: SIRENAS LLCInventors: Ippei Usui, Bryan Junn Lee, Steven Bruce Cohen, Venkat Rami Reddy Macherla, Jacob Neal Beverage, Chung-Mao Pan, Farhana Barmare, Eduardo Esquenazi
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Patent number: 10472395Abstract: Provided are cyclic peptide analogs, conjugates comprising such compounds, and pharmaceutical compositions comprising such compounds and conjugates, and methods of treating cancer with such compounds and conjugates.Type: GrantFiled: March 3, 2016Date of Patent: November 12, 2019Assignee: Sirenas LLCInventors: Venkat Rami Reddy Macherla, Alexander Wayne Schammel, Ippei Usui, Elizabeth Paige Stout, Jacob Neal Beverage, Bryan Junn Lee, Steven Bruce Cohen
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Publication number: 20190211060Abstract: Provided are cyclic peptide analogs, conjugates comprising such compounds, and pharmaceutical compositions comprising such compounds and conjugates, and methods of treating cancer with such compounds and conjugates.Type: ApplicationFiled: August 31, 2017Publication date: July 11, 2019Applicant: SIRENAS LLCInventors: Ippei USUI, Bryan Junn LEE, Steven Bruce COHEN, Venkat Rami Reddy MACHERLA, Jacob Neal BEVERAGE, Chung-Mao PAN, Farhana BARMARE, Eduardo ESQUENAZI
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Publication number: 20170015710Abstract: Provided are cyclic peptide analogs, conjugates comprising such compounds, and pharmaceutical compositions comprising such compounds and conjugates, and methods of treating cancer with such compounds and conjugates.Type: ApplicationFiled: March 3, 2016Publication date: January 19, 2017Applicant: Sirenas LLCInventors: Venkat Rami Reddy MACHERLA, Alexander Wayne SCHAMMEL, Ippei USUI, Elizabeth Paige STOUT, Jacob Neal BEVERAGE, Bryan Junn LEE, Steven Bruce COHEN
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Patent number: 8389564Abstract: Disclosed herein are compounds of Formula (I) that include a sulfonate ester, ester or ether group. Compounds of Formula (I) can be included in pharmaceutical compositions, and can be used to treating and/or ameliorating a disease or condition, such as cancer, a microbial disease and/or inflammation.Type: GrantFiled: May 14, 2012Date of Patent: March 5, 2013Inventors: Venkat Rami Reddy Macherla, Barbara Christine Potts, Rama Rao Manam, Katherine A. McArthur, Ta-Hsiang Chao, Saskia Theodora Cornelia Neuteboom
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Publication number: 20120270919Abstract: Disclosed herein are compounds of Formula (I) that include a sulfonate ester, ester or ether group. Compounds of Formula (I) can be included in pharmaceutical compositions, and can be used to treating and/or ameliorating a disease or condition, such as cancer, a microbial disease and/or inflammation.Type: ApplicationFiled: May 14, 2012Publication date: October 25, 2012Applicant: Nereus Pharmaceuticals, Inc.Inventors: Venkat Rami Reddy Macherla, Barbara Christine Potts, Rama Rao Manam, Katherine A. McArthur, Ta-Hsiang Chao, Saskia Theodora Cornelia Neuteboom
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Publication number: 20120238634Abstract: Described herein are chemical compounds and pharmaceutical compositions, including novel chemical compounds and pharmaceutical compositions thereof, useful in the treatment of various diseases and disease states. Also described are methods of synthesizing natural products and novel, structurally-related chemical compounds. More particularly, disclosed are new analogs of and processes for the preparation of compounds and pharmaceutical compositions thereof useful in the treatment of, for example, inflammation, cancer, multiple myeloma, cachexia, cardiovascular disease, anti-infectious, diabetes, otitis media, sinusitis and transplant rejection.Type: ApplicationFiled: March 9, 2012Publication date: September 20, 2012Applicant: NEREUS PHARMACEUTICALS, INC.Inventors: Michael A. Palladino, Emmanuel A. Theodorakis, Venkat Rami Reddy Macherla, Ta-Hsiang Chao, Young-Ger Suh
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Patent number: 8227503Abstract: Disclosed herein are compounds of Formula (I) that include a sulfonate ester, ester or ether group. Compounds of Formula (I) can be included in pharmaceutical compositions, and can be used to treating and/or ameliorating a disease or condition, such as cancer, a microbial disease and/or inflammation.Type: GrantFiled: March 21, 2011Date of Patent: July 24, 2012Assignee: Nereus Pharmaceuticals, Inc.Inventors: Venkat Rami Reddy Macherla, Barbara Christine Potts, Rama Rao Manam, Katherine A. McArthur, Ta-Hsiang Chao, Saskia Theodora Cornelia Neuteboom
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Patent number: 8133915Abstract: Described herein are chemical compounds and pharmaceutical compositions, including novel chemical compounds and pharmaceutical compositions thereof, useful in the treatment of various diseases and disease states. Also described are methods of synthesizing natural products and novel, structurally-related chemical compounds. More particularly, disclosed are new analogs of and processes for the preparation of compounds and pharmaceutical compositions thereof useful in the treatment of, for example, inflammation, cancer, multiple myeloma, cachexia, cardiovascular disease, anti-infectious, diabetes, otitis media, sinusitis and transplant rejection.Type: GrantFiled: January 14, 2011Date of Patent: March 13, 2012Assignees: Nereus Pharmaceuticals, Inc., The Regents of the University of CaliforniaInventors: Michael A. Palladino, Emmanuel A. Theodorakis, Venkat Rami Reddy Macherla, Ta-Hsiang Chao, Young-Ger Suh
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Publication number: 20110172285Abstract: Disclosed herein are compounds of Formula (I) that include a sulfonate ester, ester or ether group. Compounds of Formula (I) can be included in pharmaceutical compositions, and can be used to treating and/or ameliorating a disease or condition, such as cancer, a microbial disease and/or inflammation.Type: ApplicationFiled: March 21, 2011Publication date: July 14, 2011Applicant: NEREUS PHARMACEUTICALS, INC.Inventors: Venkat Rami Reddy Macherla, Barbara Christine Potts, Rama Rao Manam, Katherine A. McArthur, Ta-Hsiang Chao, Saskia Theodora Cornelia Neuteboom
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Publication number: 20110160309Abstract: Described herein are chemical compounds and pharmaceutical compositions, including novel chemical compounds and pharmaceutical compositions thereof, useful in the treatment of various diseases and disease states. Also described are methods of synthesizing natural products and novel, structurally-related chemical compounds. More particularly, disclosed are new analogs of and processes for the preparation of compounds and pharmaceutical compositions thereof useful in the treatment of, for example, inflammation, cancer, multiple myeloma, cachexia, cardiovascular disease, anti-infectious, diabetes, otitis media, sinusitis and transplant rejection.Type: ApplicationFiled: January 14, 2011Publication date: June 30, 2011Applicant: Nereus Pharmaceuticals, Inc.Inventors: Michael A. Palladino, Emmanuel A. Theodorakis, Venkat Rami Reddy Macherla, Ta-Hsiang Chao, Young-Ger Suh
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Patent number: 7910616Abstract: Disclosed herein are compounds of Formula (I) that include a sulfonate ester, ester or ether group. Compounds of Formula (I) can be included in pharmaceutical compositions, and can be used to treating and/or ameliorating a disease or condition, such as cancer, a microbial disease and/or inflammation.Type: GrantFiled: May 12, 2009Date of Patent: March 22, 2011Assignee: Nereus Pharmaceuticals, Inc.Inventors: Venkat Rami Reddy Macherla, Barbara Christine Potts, Rama Rao Manam, Katherine A. McArthur, Ta-Hsiang Chao, Saskia Theodora Cornelia Neuteboom
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Patent number: 7893299Abstract: Described herein are chemical compounds and pharmaceutical compositions, including novel chemical compounds and pharmaceutical compositions thereof, useful in the treatment of various diseases and disease states. Also described are methods of synthesizing natural products and novel, structurally-related chemical compounds. More particularly, disclosed are new analogs of and processes for the preparation of compounds and pharmaceutical compositions thereof useful in the treatment of, for example, inflammation, cancer, multiple myeloma, cachexia, cardiovascular disease, anti-infectious, diabetes, otitis media, sinusitis and transplant rejection.Type: GrantFiled: July 14, 2006Date of Patent: February 22, 2011Assignees: Nereus Pharmaceuticals, Inc., The Regents of the University of CaliforniaInventors: Michael A. Palladino, Emmanuel A. Theodorakis, Venkat Rami Reddy Macherla, Ta-Hsiang Chao, Young Ger Suh
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Publication number: 20090298906Abstract: Disclosed herein are compounds of Formula (I) that include a sulfonate ester, ester or ether group. Compounds of Formula (I) can be included in pharmaceutical compositions, and can be used to treating and/or ameliorating a disease or condition, such as cancer, a microbial disease and/or inflammation.Type: ApplicationFiled: May 12, 2009Publication date: December 3, 2009Applicant: NEREUS PHARMACEUTICALS, INC.Inventors: Venkat Rami Reddy Macherla, Barbara Christine Potts, Rama Rao Manam, Katherine A. McArthur, Ta-Hsiang Chao, Saskia Theodora Cornelia Neuteboom
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Publication number: 20080064753Abstract: Described herein are chemical compounds and pharmaceutical compositions, including novel chemical compounds and pharmaceutical compositions thereof, useful in the treatment of various diseases and disease states. Also described are methods of synthesizing natural products and novel, structurally-related chemical compounds. More particularly, disclosed are new analogs of and processes for the preparation of compounds and pharmaceutical compositions thereof useful in the treatment of, for example, inflammation, cancer, multiple myeloma, cachexia, cardiovascular disease, anti-infectious, diabetes, otitis media, sinusitis and transplant rejection.Type: ApplicationFiled: July 14, 2006Publication date: March 13, 2008Inventors: Michael A. Palladino, Emmanuel A. Theodorakis, Venkat Rami Reddy Macherla, Ta-Hsiang Chao, Young Ger Suh
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Publication number: 20060052436Abstract: Disclosed herein are novel pyrroloterpene compounds and methods for obtaining these compounds. Also disclosed are methods of treating cancer and bacterial infections using the novel pyrroloterpene compounds.Type: ApplicationFiled: August 17, 2005Publication date: March 9, 2006Inventor: Venkat Rami Reddy Macherla
