Patents by Inventor Victoria Demina

Victoria Demina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VLP FOR THE TREATMENT OF LEUKODYSTROPHIES
    Publication number: 20230310652
    Abstract: The invention relates to virus like particles (VLP) associated with an enzyme abnormally expressed in particular leukodystrophies or an expression vector encoding the enzyme or an mRNA encoding the enzyme or a combination thereof which are used in a method for the treatment of the particular leukodystrophies in a subject in the need thereof, preferably a human. The invention also relates to a pharmaceutical composition for use in a method for the treatment of the particular leukodystrophies, to an expression vector encoding the abnormally expressed enzyme and to a method of associating a VLP with the enzyme, an expression vector encoding the enzyme or an mRNA encoding the enzyme or a combination thereof.
    Type: Application
    Filed: May 19, 2021
    Publication date: October 5, 2023
    Applicant: NEUWAY Pharma GmbH
    Inventors: Victoria DEMINA, Oliver ERNST, Anke BONSE, Markus STAPF
  • VLP FOR THE TREATMENT OF A LYSOSOMAL STORAGE DISEASE
    Publication number: 20230159938
    Abstract: The invention relates to virus like particles (VLP) associated with a lysosomal enzyme or an expression vector encoding a lysosomal enzyme which are used in a method for the treatment of a lysosomal storage disease. The invention also relates to a pharmaceutical composition for use in a method for the treatment of a lysosomal storage disease, to an expression vector encoding a lysosomal enzyme and to a method of associating a VLP with an expression vector encoding a lysosomal enzyme.
    Type: Application
    Filed: November 7, 2022
    Publication date: May 25, 2023
    Applicant: NEUWAY Pharma GmbH
    Inventors: Victoria DEMINA, Marcus Stapf, Sergey Sotnikov, Heiko Manninga
  • A METHOD FOR PROVIDING A VLP DERIVED FROM JOHN CUNNINGHAM VIRUS
    Publication number: 20230157972
    Abstract: The invention relates to a method for providing a virus-like particle (VLP) derived from John Cunningham virus (JCV), relates to a VLP associated with a cargo, in particular a protein, and a drug delivery system (DDS) obtainable by said method, in particular for crossing the blood brain barrier (BBB), and a VLP containing composition. The method comprises steps of disassembly of VLP into pentamers, inducing the pentamers to aggregate and reassembly into VLP.
    Type: Application
    Filed: October 14, 2019
    Publication date: May 25, 2023
    Applicant: NEUWAY Pharma GmbH
    Inventors: Victoria DEMINA, Marcus STAFF
  • Drug delivery system based on JCV-VLP
    Patent number: 11291735
    Abstract: The invention relates to VLP derived from human polyoma virus loaded with a drug (cargo) as a drug delivery system for transporting said drug into the CNS, in particular of living humans.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: April 5, 2022
    Assignee: LIFE SCIENCE INKUBATOR BETRIEBS GMBH & CO. KG
    Inventors: Victoria Demina, Heiko Manninga, Armin Götzke, Alexander Glassmann
  • Drug delivery system and methods providing thereof
    Patent number: 11279938
    Abstract: The invention relates to a method for providing a drug delivery system, in particular for crossing the blood brain barrier (BBB), comprising a virus-like particle (VLP) derived from John Cunningham virus (JCV), a drug delivery system and novel VLP obtainable by said method. The method comprises steps of disassembly of VLP into pentamers and reassembly into VLP.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: March 22, 2022
    Assignee: NEUWAY Pharma GmbH
    Inventors: Victoria Demina, Heiko Manninga, Sergey Sotnikov, Marcus Stapf, Katja Janina Koßmann
  • A NOVEL DRUG DELIVERY SYSTEM AND METHODS PROVIDING THEREOF
    Publication number: 20210301302
    Abstract: The invention relates to a method for providing a drug delivery system, in particular for crossing the blood brain barrier (BBB), comprising a virus-like particle (VLP) derived from John Cunningham virus (JCV), a drug delivery system and novel VLP obtainable by said method. The method comprises steps of disassembly of VLP into pentamers and reassembly into VLP.
    Type: Application
    Filed: December 18, 2018
    Publication date: September 30, 2021
    Applicant: NEUWAY Pharma GmbH
    Inventors: Victoria DEMINA, Heiko MANNINGA, Sergey SOTNIKOV, Marcus STAPF, Katja Janina KOßMANN
  • VLP FOR THE TREATMENT OF A LYSOSOMAL STORAGE DISEASE
    Publication number: 20200224205
    Abstract: The invention relates to virus like particles (VLP) associated with a lysosomal enzyme or an expression vector encoding a lysosomal enzyme which are used in a method for the treatment of a lysosomal storage disease. The invention also relates to a pharmaceutical composition for use in a method for the treatment of a lysosomal storage disease, to an expression vector encoding a lysosomal enzyme and to a method of associating a VLP with an expression vector encoding a lysosomal enzyme.
    Type: Application
    Filed: December 17, 2019
    Publication date: July 16, 2020
    Applicant: NEUWAY Pharma GmbH
    Inventors: Victoria DEMINA, Marcus STAPF, Sergey Sotnikov, Heiko MANNINGA
  • NOVEL DRUG DELIVERY SYSTEM BASED ON JCV-VLP
    Publication number: 20190201549
    Abstract: The invention relates to VLP derived from human polyoma virus loaded with a drug (cargo) as a drug delivery system for transporting said drug into the CNS, in particular of living humans.
    Type: Application
    Filed: March 15, 2019
    Publication date: July 4, 2019
    Applicant: LIFE SCIENCE INKUBATOR BETRIEBS GMBH & CO. KG
    Inventors: Victoria Demina, Heiko Manninga, Armin Götzke, Alexander Glassmann
  • NOVEL DRUG DELIVERY SYSTEM BASED ON JCV-VLP
    Publication number: 20180296700
    Abstract: The invention relates to VLP derived from human polyoma virus loaded with a drug (cargo) as a drug delivery system for transporting said drug into the CNS, in particular of living humans.
    Type: Application
    Filed: June 26, 2018
    Publication date: October 18, 2018
    Applicant: LIFE SCIENCE INKUBATOR BETRIEBS GMBH & CO. KG
    Inventors: Victoria Demina, Heiko Manninga, Armin Goetzke, Alexander Glassmann
  • Method for purifying virus-like particles (VLP)
    Patent number: 9868762
    Abstract: The invention relates to a method for purifying compositions containing virus-like particles (VLP), wherein a VLP-containing composition is filtered through a filter medium, in particular through a membrane, having a molecular weight cut off (MWCO) of more than 30 kDa, and the cell culture supernatant of VLP-expressing cells is used as a VLP-containing composition. The invention further relates to a VLP-containing composition which can be produced by this method.
    Type: Grant
    Filed: August 1, 2012
    Date of Patent: January 16, 2018
    Assignee: LIFE SCIENCE INKUBATOR BETRIEBS GMBH & CO. KG
    Inventors: Victoria Demina, Heiko Manninga
  • A NOVEL DRUG DELIVERY SYSTEM BASED ON JCV-VLP
    Publication number: 20150045417
    Abstract: The invention relates to VLP derived from human polyoma virus loaded with a drug (cargo) as a drug delivery system for transporting said drug into the CNS, in particular of living humans.
    Type: Application
    Filed: March 6, 2013
    Publication date: February 12, 2015
    Inventors: Victoria DEMINA, Heiko MANNINGA, Armin GOTZKE, Alexander GLASSMANN
  • METHOD FOR PURIFYING VIRUS-LIKE PARTICLES (VLP)
    Publication number: 20140309408
    Abstract: The invention relates to a method for purifying compositions containing virus-like particles (VLP), wherein a VLP-containing composition is filtered through a filter medium, in particular through a membrane, having a molecular weight cut off (MWCO) of more than 30 kDa, and the cell culture supernatant of VLP-expressing cells is used as a VLP-containing composition. The invention further relates to a VLP-containing composition which can be produced by this method.
    Type: Application
    Filed: August 1, 2012
    Publication date: October 16, 2014
    Applicant: LIFE SCIENCE INKUBATOR BETRIEBS GMBH & CO. KG
    Inventors: Victoria Demina, Heiko Manninga