Abstract: One example may include detecting, via a printer, a radio enabled label, retrieving, via the printer, an identifier from a local wireless communication device to assign to the radio enabled label, sending, via the printer, the identifier to a memory of the radio enabled label, and assigning the identifier to a plurality of microcontrollers embedded in the radio enabled label.

Abstract: A system, including, associating a wireless tracker with an asset, wherein the wireless tracker emits a tracker identification and a sensor payload including a fixed identification, receiving by at least one of a plurality of mobile devices the tracker identification, the sensor payload and an associated location of the at least one of the plurality of mobile devices and monitoring the tracker identification and the associated location of the at least one of the plurality of mobile devices.

Abstract: A system, including a housing having a front and a rear, a controller contained within the housing, a trigger module contained within the housing, the trigger module coupled to the controller, the trigger module receiving a trigger signal and outputting a range measurement signal, a range module contained within the housing, the ranging module coupled to the controller, the range module outputs a range data signal in response to the range measurement signal, a memory module contained within the housing, the memory module coupled to the controller, the memory module storing the range data signal, a wireless transceiver contained within the housing, the wireless transceiver coupled to the controller the wireless transceiver outputting the stored range data signal and an affixment coupled to the housing rear enabling physical connection to a shipping structure.

Abstract: A method, including, associating a wireless tracker with an asset, tracking a location of the asset via the wireless tracker, determining a recipient mobile device authorized to accept receipt of the asset, determining a recipient mobile device holder is authorized to accept receipt of the asset, determining if the location of the asset is within a defined delivery location, determining if the authorized recipient mobile device is within the defined delivery location, sending a passcode to the authorized recipient mobile device if the authorized recipient mobile device location and the location of the asset are within the defined delivery location, receiving an authenticated passcode from the authorized recipient mobile device within the defined delivery location and notifying a delivery agent that delivery of the asset is approved.

Abstract: Polynucleotides are engineered to hybridize to one another to form a functional guide nucleic acid having an editing template. The hybridized guide nucleic acids may be used with template-based gene editors to write an edit into a target genomic location using the editing template as a template for the edit.

Abstract: Embodiments of the present disclosure include systems, methods, and devices for tracking a shipment using a wireless tracker. In such embodiments, the wireless tracker determines a location of the wireless tracker device and regulates battery usage of wireless tracker based on the location. In addition, the wireless tracker is configured to determine a current location of the wireless tracker device at one or more intervals such that the one or more intervals are based on a delivery route of the shipment. Moreover, the wireless tracker is configured to receive and verify one or more codes to for a chain of custody of the shipment. Also, the wireless tracker is configured to determine a trigger event based on the location of the wireless tracker device and/or sensor information as well as send a notification to a computer server based on the trigger event.

Abstract: Embodiments of the present disclosure include systems, methods, and devices for tracking a shipment using a wireless tracker. In such embodiments, the wireless tracker determines a location of the wireless tracker device and regulates battery usage of wireless tracker based on the location. In addition, the wireless tracker is configured to determine a current location of the wireless tracker device at one or more intervals such that the one or more intervals are based on a delivery route of the shipment. Moreover, the wireless tracker is configured to receive and verify one or more codes to for a chain of custody of the shipment. Also, the wireless tracker is configured to determine a trigger event based on the location of the wireless tracker device and/or sensor information as well as send a notification to a computer server based on the trigger event.

Abstract: Provided herein are methods for generating single-cell molecular analysis comprising a) delivering one or more proximity dependent probes to a cell population, wherein each proximity dependent probe comprises a target binding region configured to bind a target RNA and a primer binding site region; b) linking bound proximity dependent probes; c) isolating single cells from the cell population in separate individual discrete volumes, the individual discrete volumes further comprising a primer pair and amplification reagents, wherein the primer pair binds to the primer binding sites of the ligation dependent probes, and wherein at least one primer comprises a barcode sequence that uniquely identifies the individual discrete volume; d) amplifying the ligated probes using the primer pair, wherein the barcode is incorporated into each resulting amplicon; and e) quantifying target RNAs in each individual cell based at least in part on sequencing the resulting amplicons.

Abstract: A system, including, associating a wireless tracker with an asset, wherein the wireless tracker emits a tracker identification and a sensor payload including a fixed identification, receiving by at least one of a plurality of mobile devices the tracker identification, the sensor payload and an associated location of the at least one of the plurality of mobile devices and monitoring the tracker identification and the associated location of the at least one of the plurality of mobile devices.

Abstract: Described herein are mutations in the CH1/CL interface and CH3 constant regions of a bispecific antibody which facilitate heterodimerization and methods for the efficient production of bispecific antibodies. Also disclosed are therapeutic and diagnostic methods for using the antibodies.

Abstract: Provided herein are methods for generating single-cell molecular analysis comprising a) delivering one or more proximity dependent probes to a cell population, wherein each proximity dependent probe comprises a target binding region configured to bind a target RNA and a primer binding site region; b) linking bound proximity dependent probes; c) isolating single cells from the cell population in separate individual discrete volumes, the individual discrete volumes further comprising a primer pair and amplification reagents, wherein the primer pair binds to the primer binding sites of the ligation dependent probes, and wherein at least one primer comprises a barcode sequence that uniquely identifies the individual discrete volume; d) amplifying the ligated probes using the primer pair, wherein the barcode is incorporated into each resulting amplicon; and e) quantifying target RNAs in each individual cell based at least in part on sequencing the resulting amplicons.

Abstract: A method, including recognizing an indicia pattern on an asset utilizing a mobile device based augmented reality vision system, prompting one of acceptance and disapproval of the indicia pattern on the asset, detecting a wireless signal from a wireless tracking device if the asset indicia pattern is accepted, pairing the asset and the wireless tracking device and prompting one of confirmation and refusal of the pairing.

Abstract: This disclosure relates to novel peptide agents, e.g., antibodies and antigen-binding fragments thereof, that bind hemagglutinin protein of influenza viruses, and methods of their use.

Abstract: A method, including, associating a wireless tracker with an asset, tracking a location of the asset via the wireless tracker, determining a recipient mobile device authorized to accept receipt of the asset, determining a recipient mobile device holder is authorized to accept receipt of the asset, determining if the location of the asset is within a defined delivery location, determining if the authorized recipient mobile device is within the defined delivery location, sending a passcode to the authorized recipient mobile device if the authorized recipient mobile device location and the location of the asset are within the defined delivery location, receiving an authenticated passcode from the authorized recipient mobile device within the defined delivery location and notifying a delivery agent that delivery of the asset is approved.

Abstract: A system, including a housing having a front and a rear, a controller contained within the housing, a trigger module contained within the housing, the trigger module coupled to the controller, the trigger module receiving a trigger signal and outputting a range measurement signal, a range module contained within the housing, the ranging module coupled to the controller, the range module outputs a range data signal in response to the range measurement signal, a memory module contained within the housing, the memory module coupled to the controller, the memory module storing the range data signal, a wireless transceiver contained within the housing, the wireless transceiver coupled to the controller the wireless transceiver outputting the stored range data signal and an affixment coupled to the housing rear enabling physical connection to a shipping structure.

Abstract: Embodiments of the present disclosure include systems, methods, and devices for tracking a shipment using a wireless tracker. In such embodiments, the wireless tracker determines a location of the wireless tracker device and regulates battery usage of wireless tracker based on the location. In addition, the wireless tracker is configured to determine a current location of the wireless tracker device at one or more intervals such that the one or more intervals are based on a delivery route of the shipment. Moreover, the wireless tracker is configured to receive and verify one or more codes to for a chain of custody of the shipment. Also, the wireless tracker is configured to determine a trigger event based on the location of the wireless tracker device and/or sensor information as well as send a notification to a computer server based on the trigger event.

Abstract: Embodiments of the present disclosure include systems, methods, and devices for tracking a shipment using a wireless tracker. In such embodiments, the wireless tracker determines a location of the wireless tracker device and regulates battery usage of wireless tracker based on the location. In addition, the wireless tracker is configured to determine a current location of the wireless tracker device at one or more intervals such that the one or more intervals are based on a delivery route of the shipment. Moreover, the wireless tracker is configured to receive and verify one or more codes to for a chain of custody of the shipment. Also, the wireless tracker is configured to determine a trigger event based on the location of the wireless tracker device and/or sensor information as well as send a notification to a computer server based on the trigger event.

Abstract: A system, including, associating a wireless tracker with an asset, wherein the wireless tracker emits a tracker identification and a sensor payload including a fixed identification, receiving by at least one of a plurality of mobile devices the tracker identification, the sensor payload and an associated location of the at least one of the plurality of mobile devices and monitoring the tracker identification and the associated location of the at least one of the plurality of mobile devices.

Abstract: Isolated monoclonal antibodies which bind to Ebola virus glycoprotein and related antibody-based compositions and molecules are disclosed. Also disclosed are therapeutic and diagnostic methods for using the antibodies.

Abstract: The present invention provides antibodies (e.g., monoclonal antibodies, human antibodies, humanized antibodies, etc.), which bind to multiple influenza strains. Such antibodies are useful, for example, in the prophylaxis, treatment, diagnosis, and/or study of influenza.