Patents by Inventor VIJAYA RAJ KUNIYIL KULANGARA

VIJAYA RAJ KUNIYIL KULANGARA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMAGING TUBERCULOSIS WITH PYRAZINAMIDE CONTRAST AGENTS
    Publication number: 20130149249
    Abstract: The present invention provides novel in vivo imaging agents useful for detecting the presence of mycobacteria using in vivo imaging methods. Also provided by the present invention is a precursor compound useful in the synthesis of the in vivo imaging agents of the invention, and a method to obtain the in vivo imaging agent of the invention using said precursor compound. Methods of in vivo imaging and diagnosis in which the in vivo imaging agent of the invention finds use are also provided.
    Type: Application
    Filed: August 22, 2011
    Publication date: June 13, 2013
    Applicant: GE HEALTHCARE LIMITED
    Inventors: Vijaya Raj Kuniyil Kulangara, Ravi Hegde
  • NITROIMIDAZOLE DERIVATIVES
    Publication number: 20130078185
    Abstract: The present invention provides novel compounds useful in the treatment and diagnosis of mycobacterial infections. Compounds of the present invention have enhanced biological properties as compared to the related known compounds. The present invention also provides a precursor compound useful in the synthesis of certain compounds of the invention, and a method to obtain these compounds using said precursor compound. Methods of treatment and diagnosis in which the compounds of the invention fmd use are also provided.
    Type: Application
    Filed: May 31, 2011
    Publication date: March 28, 2013
    Applicant: GE HEALTHCARE LIMITED
    Inventors: Vijaya Raj Kuniyil Kulangara, Chandan Ramaswamy Atreya
  • ALDH: A COMPOUND FOR CANCER STEM CELL IMAGING
    Publication number: 20120251449
    Abstract: The present invention claims fluoro- & iodo-containing aldehydes as ALDH substrates for use as diagnostic imaging agents or as therapeutic agents. The aldehydes are both directly and indirectly attached to an aromatic or a straight chain ring. ALDH activity was monitored either by the formation of acid-product or consumption of aldehyde substrates.
    Type: Application
    Filed: December 22, 2010
    Publication date: October 4, 2012
    Inventors: Vijaya Raj Kuniyil Kulangara, Alan Cuthbertson, Peter Iveson, Chitralekha Rangaswamy, Veena Rao, Rajiv Bhalla
  • IMAGING AND RADIOTHERAPY METHODS
    Publication number: 20110286922
    Abstract: The present invention relates to in vivo imaging and radiotherapeutic methods and agents which target the enzyme aldehyde dehydrogenase (ALDH) and that are suitable for the in vivo imaging of tumours and treatment of cancer.
    Type: Application
    Filed: October 20, 2009
    Publication date: November 24, 2011
    Inventors: Alan Cuthbertson, Peter Brian Iveson, Rajiv Bhalla, Vijaya Raj Kuniyil Kulangara
  • PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRIDONE CARBOXYLIC ACIDS
    Publication number: 20100076199
    Abstract: The present invention relates to methods for the preparation of pyridone carboxylic acids for use as intermediates in the preparation of various synthetic organic compounds. The pyridone carboxylic acids can for example be used as intermediates in the production of potent antitumor agents, antifungal agents, antiviral agents, psychotherapeutic agents or contrast imaging agents for MRI.
    Type: Application
    Filed: September 17, 2009
    Publication date: March 25, 2010
    Applicant: GE HEALTHCARE AS
    Inventors: VIJAYA RAJ KUNIYIL KULANGARA, TILAK T. RAJ