Patents by Inventor Vijayavitthal Thippannachar Mathad
Vijayavitthal Thippannachar Mathad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230122169Abstract: The present invention relates to a crystal form of (?)-Cibenzoline succinate. In addition, the present invention relates to a method for preparing (?)-Cibenzoline succinate having a chiral purity of 99.9% or higher. Additionally, the present invention provides a method for preparing (?)-Cibenzoline succinate and a crystal form thereof.Type: ApplicationFiled: September 29, 2019Publication date: April 20, 2023Inventors: Srinivas Reddy Desi Reddy, Vijayavitthal Thippannachar Mathad, Dnyandev Ragho Rane, Vikas Shivaji Patil
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Patent number: 9139537Abstract: A novel ammonium salt of Bosentan of formula (VIII); has been disclosed. The salt may be either crystalline or amorphous or mixture of Crystalline and amorphous form. A novel single pot process for the preparations of ammonium salt of Bosentan has been disclosed. The process comprises reacting the 4,6-dichloro-5-(2-methoxyphenoxy)-2,2?-bipyrimidine with 4-tert-butylbenzenesulfonamide in the presence of solvent and a base; adding ethylene glycol to the reaction mass and isolating the ammonium salt of Bosentan. The ammonium salt of Bosentan is converted into Bosentan and further into Bosentan Monohydrate which are substantially free from dimer impurity and 6-hydroxy impurity.Type: GrantFiled: March 28, 2011Date of Patent: September 22, 2015Assignee: Megafine Pharma(P) Ltd.Inventors: Vijayavitthal Thippannachar Mathad, Navnath Chintaman Niphade, Kunal Madhav Jagtap, Chandrashekar Trimbak Gaikwad
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Publication number: 20150152040Abstract: A method for the preparation of Cinacalcet is disclosed comprising treating (R)-1-naphthyl ethylamine with an aromatic aldehyde to form (1R)-1-(2-naphthyl)-N-(aryl methylene)ethanamine derivative of Formula (IV), which is further treated with 1-(3-halopropyl)-3-(trifluoromethyl)benzene of Formula (V) to obtain an iminium salt of Formula (VI), followed by hydrolysis to obtain Cinacalcet free base.Type: ApplicationFiled: January 20, 2015Publication date: June 4, 2015Inventors: Vijayavitthal Thippannachar Mathad, Navnath Chintaman Niphade, Gorakshanath Balasaheb Shinde, Sharad Subhash Ippar, Shrikant Prataprao Deshmukh, Raghavendra Kumar Panchangam
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Patent number: 8969623Abstract: A method for the preparation of Cinacalcet is disclosed comprising treating (R)-1-naphthyl ethylamine with an aromatic aldehyde to form (1R)-1-(2-naphthyl)-N-(aryl methylene)ethanamine derivative of Formula (IV), which is further treated with 1-(3-halopropyl)-3-(trifluoromethyl)benzene of Formula (V) to obtain an iminium salt of Formula (VI), followed by hydrolysis to obtain Cinacalcet free base.Type: GrantFiled: October 11, 2013Date of Patent: March 3, 2015Assignee: Amneal Pharmaceuticals, LLCInventors: Vijayavitthal Thippannachar Mathad, Navnath Chintaman Niphade, Gorakshanath Balasaheb Shinde, Sharad Subhash Ippar, Shrikant Prataprao Deshmukh, Raghavendra Kumar Panchangam
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Publication number: 20150011756Abstract: An improved process for the preparation of Rivaroxaban wherein the process substantially eliminates the potential impurities. process for preparation of Rivaroxaban which uses a novel intermediate. A process for preparing the novel intermediate which is used for the preparation of Rivaroxaban.Type: ApplicationFiled: February 5, 2013Publication date: January 8, 2015Inventors: Vijayavitthal Thippannachar Mathad, Nilesh Sudhir Patil, Navnath Chintaman Niphade, Anil Chaturlal Mali, Mahendra Bhagirath Bodake, Sharad Subhash Ippar, Rajesh Talla
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Publication number: 20140081048Abstract: A method for the preparation of Cinacalcet is disclosed comprising treating (R)-1-naphthyl ethylamine with an aromatic aldehyde to form (1R)-1-(2-naphthyl)-N-(aryl methylene)ethanamine derivative of Formula (IV), which is further treated with 1-(3-halopropyl)-3-(trifluoromethyl)benzene of Formula (V) to obtain an iminium salt of Formula (VI), followed by hydrolysis to obtain Cinacalcet free base.Type: ApplicationFiled: October 11, 2013Publication date: March 20, 2014Applicants: Megafine Pharma (P) Ltd., Amneal Pharmaceuticals, LLCInventors: Vijayavitthal Thippannachar Mathad, Navnath Chintaman Niphade, Gorakshanath Balasaheb Shinde, Sharad Subhash Ippar, Shrikant Prataprao Deshmukh, Raghavendra Kumar Panchangam
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Publication number: 20130296560Abstract: A novel ammonium salt of Bosentan of formula (VIII); has been disclosed. The salt may be either crystalline or amorphous or mixture of Crystalline and amorphous form. A novel single pot process for the preparations of ammonium salt of Bosentan has been disclosed. The process comprises reacting the 4,6-dichloro-5-(2-methoxyphenoxy)-2,2?-bipyrimidine with 4-tert-butylbenzenesulfonamide in the presence of solvent and a base; adding ethylene glycol to the reaction mass and isolating the ammonium salt of Bosentan. The ammonium salt of Bosentan is converted into Bosentan and further into Bosentan Monohydrate which are substantially free from dimer impurity and 6-hydroxy impurity.Type: ApplicationFiled: March 28, 2011Publication date: November 7, 2013Applicant: Megafine Pharma (P) Ltd.Inventors: Vijayavitthal Thippannachar Mathad, Navnath Chintaman Niphade, Kunal Madhav Jagtap, Chandrashekar Trimbak Gaikwad
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Patent number: 8575395Abstract: A method for the preparation of Cinacalcet is disclosed comprising treating (R)-1-naphthyl ethylamine with an aromatic aldehyde to form (1R)-1-(2-naphthyl)-N-(aryl methylene)ethanamine derivative of Formula (IV), which is further treated with 1-(3-halopropyl)-3-(trifluoromethyl)benzene of Formula (V) to obtain an iminium salt of Formula (VI), followed by hydrolysis to obtain Cinacalcet free base.Type: GrantFiled: September 6, 2011Date of Patent: November 5, 2013Assignees: Amneal Pharmaceuticals, LLC, Megafine Pharma (P) Ltd.Inventors: Vijayavitthal Thippannachar Mathad, Navnath Chintaman Niphade, Gorakshanath Balasaheb Shinde, Sharad Subhash Ippar, Shrikant Prataprao Deshmukh, Raghavendra Kumar Panchangam
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Patent number: 8217039Abstract: Intimate mixtures of aprepitant crystalline Form I and crystalline Form II, having specific weight ratios of the forms.Type: GrantFiled: March 29, 2007Date of Patent: July 10, 2012Assignees: Dr. Reddy's Laboratories Ltd., Dr. Reddy's Laboratories, Inc.Inventors: Vijayavitthal Thippannachar Mathad, Pravinchandra Jayantilal Vankawala, Raviram Chandrasekhar Elati, Prabhakar Macharla, Srinivas Gangula, Naveen Kumar Kolla, Ravi Kumar Komareddy, Surya Narayana Devarkonda, Subbareddy Peddireddy
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Patent number: 7943781Abstract: A process comprising cyclizing 3-amino-4-butyramido-5-methylbenzoic acid to form 2-n-propyl-4-methyl-benzimidazole-6-carboxylic acid.Type: GrantFiled: October 18, 2005Date of Patent: May 17, 2011Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.Inventors: Sundaram Venkataraman, Vijayavitthal Thippannachar Mathad, Srirami Reddy Kikkuru, Srinivasan Neti, Raveendra Reddy Chinta, Muthulingam Arunagiri, Lalitha Kumari Routhu
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Publication number: 20100298327Abstract: Intimate mixtures of aprepitant crystalline Form I and crystalline Form II, having specific Hweight ratios of the forms.Type: ApplicationFiled: March 29, 2007Publication date: November 25, 2010Applicants: DR. REDDY'S LABORATORIES LTD., DR. REDDY'S LABORATORIES, INC.Inventors: Vijayavitthal Thippannachar Mathad, Pravinchandra Jayantilal Vankawala, Raviram Chandrasekhar Elati, Prabhakar Macharla, Srinivas Gangula, Naveen Kumar Kolla, Ravi Kumar Komareddy, Surya Narayana Devarkonda, Subbareddy Peddireddy
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Publication number: 20090326230Abstract: The present invention relates to solifenacin in solid form and a process for its preparation and to a process for the preparation of (1S)-1-Phenyl-1,2,3,4-tetrahydro-isoquinoline, a key intermediate in the synthesis of solifenacin and its salts.Type: ApplicationFiled: July 18, 2007Publication date: December 31, 2009Applicants: Dr. Reddy's Laboratories Ltd., Dr. Reddy's Laboratories, Inc.Inventors: Vijayavitthal Thippannachar Mathad, Jaydeepkumar Dahyabhai Lilakar, Goverdhan Gilla, Sriramireddy Kikkuru, Raveendra Reddy Chinta, Swaroopa Dudipala
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Publication number: 20090209541Abstract: Pharmaceutical compositions comprising aprepitant, wherein aprepitant solubility in aqueous media is enhanced.Type: ApplicationFiled: June 18, 2007Publication date: August 20, 2009Applicants: Dr. Reddy's Laboratories Ltd., Dr. Reddy's Laboratories, Inc.Inventors: Paras Jain, Umesh V. Barabde, Ravinder Kodipyaka, Indu Bhushan, Vijayavitthal Thippannachar Mathad, Pravinchandra Jayantilal Vankawala, Kolla Naveen Kumar, Arunagiri Muthulingam, Gangula Srinivas, Chlamala Subrahmanyeswara Rao, Elati Ravi Ram Chandrasekhar
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Publication number: 20080214535Abstract: A coprecipitate comprising amorphous aprepitant and a pharmaceutically acceptable carrier is prepared by rapidly removing solvent from a solution containing aprepitant and the carrier.Type: ApplicationFiled: July 31, 2006Publication date: September 4, 2008Applicants: DR. REDDY'S LABORATORIES LTD., DR. REDDY'S LABORATORIES, INC.Inventors: Vijayavitthal Thippannachar Mathad, Pravinchandra Vankawala Jayantilal, Chandrasekhar Ravi Ram Elati, Subrahmanyeswara Rao Chlamala, Naveen Kumar Kolla, Srinivas Gangula, Srirami Reddy Kikkuru, Srinivasan Neti, Raveendra Reddy Chinta
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Publication number: 20080146844Abstract: A process for preparing tolterodine with high purity.Type: ApplicationFiled: January 28, 2008Publication date: June 19, 2008Applicants: DR. REDDY'S LABORATORIES LIMITED, DR. REDDY'S LABORATORIES, INC.Inventors: Sundaram Venkataraman, Vijayavitthal Thippannachar Mathad, Kikkuru Srirami Reddy, Neti Srinivasan, Chinta Raveendra Reddy, Muthulingam Arunagiri, Routhu Lalitha Kumari
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Publication number: 20080114173Abstract: A process for preparing crystalline form I of donepezil hydrochloride comprises: a) condensing 5,6-dimethoxy-2-piperidin-4-yl-methyl-indan-1-one with benzyl bromide and reacting a condensation product with hydrobromic acid to form donepezil hydrobromide; and b) hydrolyzing donepezil hydrobromide, followed by reacting with aqueous hydrochloric acid.Type: ApplicationFiled: August 1, 2005Publication date: May 15, 2008Inventors: Vijayavitthal Thippannachar Mathad, Sharat Pandurang Narasapur, Pravinchandra Jayantila Vankawala, Manoj Ramesh Khakar, Ravi rama Chandra Shekar Elati, Subrahmanyeswar Rao Chalamala, Arun T.
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Patent number: 7355077Abstract: A process for preparing tolterodine with high purity.Type: GrantFiled: October 26, 2005Date of Patent: April 8, 2008Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.Inventors: Sundaram Venkataraman, Vijayavitthal Thippannachar Mathad, Kikkuru Srirami Reddy, Neti Srinivasan, Chinta Raveendra Reddy, Muthulingam Arunagiri, Routhu Lalitha Kumari
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Publication number: 20070287840Abstract: A process for preparing telmisartan and intermediates formed in the process.Type: ApplicationFiled: October 18, 2005Publication date: December 13, 2007Inventors: Sundaram Venkataraman, Vijayavitthal Thippannachar Mathad, Srirami Kikkuru, Srinivasan Neti, Raveendra Chinta, Muthulingam Arunagiri, Lalitha Routhu
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Patent number: 6933389Abstract: An improved process for making crystalline Form-I of Pantoprazole sodium sesquihydrate is provided.Type: GrantFiled: September 2, 2003Date of Patent: August 23, 2005Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.Inventors: Manne Satyanarayana Reddy, Sajja Eswaraiah, Vijayavitthal Thippannachar Mathad, Pondichetty Anilkumar, Elati Ravi Ram Chandrashekar, Govindan Shanmugam
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Publication number: 20040186139Abstract: An improved process for making crystalline Form-I of Pantoprazole sodium sesquihydrate is provided.Type: ApplicationFiled: September 2, 2003Publication date: September 23, 2004Applicants: DR. REDDY'S LABORATORIES LIMITED, DR. REDDY'S LABORATORIES, INC.Inventors: Manne Satyanarayana Reddy, Sajja Eswaraiah, Vijayavitthal Thippannachar Mathad, Pondichetty Anilkumar, Elati Ravi Ram Chandrashekar, Govindan Shanmugam