Patents by Inventor Vilma Sabbatini

Vilma Sabbatini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amides, useful in the inhibition of IL-8-induced chemotaxis of neutrophils
    Patent number: 7705050
    Abstract: N-(2-aryl-propionyl)-amides of formula (I) are described. The process for their preparation and pharmaceutical preparations thereof are also described. The amides of the invention are useful in the prevention and treatment of tissue damage due to the exacerbate recruitment of polymorphonuclear neutrophils (leukocytes PMN) at the inflammatory sites. In particular, the invention relates to the R enantiomers of N-(2-aryl-propionyl)amides of formula (I) for use in the inhibition of the chemotaxis of neutrophils induced by IL-8. The compounds of the invention are used in the treatment of psoriasis, ulcerative cholitis, glomerular nephritis, acute respiratory insufficiency, idiopathic fibrosis, and rheumatoid arthritis.
    Type: Grant
    Filed: February 6, 2001
    Date of Patent: April 27, 2010
    Inventors: Marcello Allegretti, Riccardo Bertini, Cinzia Bizzarri, Vilma Sabbatini, Ginfranco Caselli, Maria Candida Cesta, Carmelo Gandolfi, Janete Peloia Barroso Gandolfi, legal representative, Giulio Agostino Gandolfi, legal representative, Maria Carla Gandolfi, legal representative, Arrigo Aldo Gandolfi, legal representative, Francesco Colotta
  • Amide of R-2-(aminoaryl)-propionic acid for use in the prevention of leucocyte activation
    Patent number: 7217707
    Abstract: N-(2-aminoaryl-propionyl)-amides of formula (1) are described. The process for their preparation and pharmaceutical preparations thereof are also described. The amides of the invention are useful in the prevention and treatment of tissue damage due to the exacerbate recruitment of polymorphonuclear neutrophils (leukocytes PMN) at the inflammatory sites. In particular, the invention relates to the R enantiomers of 2-(aminoaryl)-propionyl amides of formula (1) for use in the ihibition of the chemotaxis of neutrophils induced by IL-8. The compounds of the invention are used in the treatment of psoriasis, ulcerative cholitis, glomerular nephritis, acute respiratory insufficiency, idiopathic fibrosis, and rheumatoid arthritis.
    Type: Grant
    Filed: April 11, 2001
    Date of Patent: May 15, 2007
    Assignee: Dompe S.p.A.
    Inventors: Marcello Allegretti, Riccardo Bertini, Cinzia Bizzarri, Vilma Sabbatini, Ginfranco Caselli, Maria Candida Cesta, Janete Peloia Barroso Gandolfi, legal representative, Giulio Agostino Gandolfi, legal representative, Maria Carla Gandolfi, legal representative, Arrigo Aldo Gandolfi, legal representative, Francesco Colotta, Carmelo Gandolfi, deceased
  • N-(2-aryl-propionyl)-sulfonamides and pharmaceutical preparations containing them
    Patent number: 6887903
    Abstract: The compounds of formula 1 wherein R and R2 are as defined in the disclosure, are useful in the prevention and treatment of tissue damage due to exacerbated recruitment of polymorphonuclear neutrophils (PMN leukocytes) at the inflammatory sites.
    Type: Grant
    Filed: October 14, 1999
    Date of Patent: May 3, 2005
    Assignee: Dompe S.p.A.
    Inventors: Riccardo Bertini, Cinzia Bizzarri, Vilma Sabbatini, Gianfranco Caselli, Marcello Allegretti, Maria Candida Cesta, Carmelo Gandolfi, Marco Mantovanini, Francesco Colotta, Stefano Porzio
  • N-(2-aryl-propionyl)-sulfonamides and pharmaceutical preparations containing them
    Patent number: 6881755
    Abstract: The compounds of formula 1, wherein R and R2 are as defined in the disclosure, are useful in the prevention and treatment of tissue damage due to exacerbated recruitment of polymorphonuclear neutrophils (PMN leukocytes) at the inflammatory sites.
    Type: Grant
    Filed: June 13, 2003
    Date of Patent: April 19, 2005
    Assignee: Dompé S.p.A.
    Inventors: Riccardo Bertini, Cinzia Bizzarri, Vilma Sabbatini, Gianfranco Caselli, Marcello Allegretti, Maria Candida Cesta, Carmelo Gandolfi, Marco Mantovanini, Francesco Colotta, Stefano Porzio
  • Amide of r-2-(aminoaryl)-propionic acid for use in theprevention of leucocyte activation
    Publication number: 20040186146
    Abstract: N-(2-aminoaryl-propionyl)-amides of formula (1) are described.
    Type: Application
    Filed: October 30, 2003
    Publication date: September 23, 2004
    Inventors: Marcello Allegretti, Riccardo Bertini, Cinzia Bizzarri, Vilma Sabbatini, Ginfranco Caselli, Maria Candida Cesta, Carmelo Gandolfi, Francesco Colotta
  • Amides, useful in the inhibition of il-8-induced chemotaxis of neutrophils
    Publication number: 20040181073
    Abstract: N-(2-aryl-propionyl)-amides of formula (I) are described.
    Type: Application
    Filed: October 27, 2003
    Publication date: September 16, 2004
    Inventors: Marcelo Allegretti, Riccardo Bertini, Cinzia Bizzarri, Vilma Sabbatini, Ginfranco Caselli, Maria Candida Cesta, Carmelo Gandolfi, Janete Peloia Barroso Gandolfi, Giulio Agostino Gandolfi, Maria Carla Gandolfi, Arrigo Aldo Gandolfi, Francesco Colotta
  • N - ( 2 - aryl - propionyl ) - sulfonamides and pharmaceutical preparations containing them
    Publication number: 20030216392
    Abstract: The compounds of formula 1, 1
    Type: Application
    Filed: June 13, 2003
    Publication date: November 20, 2003
    Applicant: Dompe S.p.A.
    Inventors: Riccardo Bertini, Cinzia Bizzarri, Vilma Sabbatini, Gianfranco Caselli, Marcello Allegretti, Maria Candida Cesta, Carmelo Gandolfi, Marco Mantovanini, Francesco Colotta, Stefano Porzio