Abstract: A capacitive electrical conductivity sensor is integrated into a water meter. The sensor is used to determine water conductivity, which may be used to determine water quality. A model of a capacitor, a flow of water, and a plastic conduit used to conduct the flow of water passing through a water meter is defined. The model may include a circuit having a constant phase element (CPE) connected to a resistor Rb and a capacitor Cb in parallel. An input signal may be applied to the actual capacitor (not the model) over a range of frequencies. Current flow associated with several frequencies may be used to identify values of Q0 and alpha of the CPE of the model. A value for the resistor Rb is identified using values obtained from measurements. A conductivity of the flow of water may be derived using input values comprising Rb, and the values of Q0 and alpha of the CPE of the model.

Abstract: The invention relates to a method for producing a digital representation for producing an appliance for a living body, particularly to be applied against the external surface of the living body. The invention is particularly intended for the production of orthoses and prostheses. The method according to the invention allows the digital representation of an appliance using a modelling of the internal and external structures of the living body to be fitted with an appliance.

Abstract: A method for the radiographic imaging of a three-dimensional internal structure which forms part of an object located within a field of view, a radiographic image processing device and a radiographic imaging device, which are particularly suitable for locating a characteristic point of an internal structure on a radiographic image.

Abstract: The invention relates to a method for producing a digital representation for producing an appliance for a living body, particularly to be applied against the external surface of the living body. The invention is particularly intended for the production of orthoses and prostheses. The method according to the invention allows the digital representation of an appliance using a modelling of the internal and external structures of the living body to be fitted with an appliance.

Abstract: Disclosed is the in vitro use of at least one lectin which recognises the fucose alpha(1-2) galactose unit for labelling cancer stem cells of organs involved in respiration, in order to obtain labelled cancer stem cells of organs involved in respiration, in a biological sample. In one particular embodiment, the at least one lectin is chosen from the lectins Ulex Europaeus agglutinin 1 (UEA-1) or the homologue thereof, Trichosanthes japonica agglutinin II (TJA-II), Agaricus Bisporus agglutinin (ABA), Amaranthus Caudatus agglutinin (ACA), jacalin, Griffonia Simplicifolia lectin I (GSL-I) and Griffonia Simplicifolia lectin II (GSL-II). In one particular embodiment, the organ involved in respiration is chosen from the lungs, the larynx, the pharynx, the mouth, the nose, the throat, the tongue, the sinuses, the trachea and the saliva glands including the tonsils and the parotid gland.

Abstract: Disclosed is the in vitro use of at least one lectin for marking cancer stem cells of hormone-dependent cancer target organs, selected from the lectins Maackia amurensis lectin II (MAH-II), Euonymus europaeus lectin (EEL), Psophocarpus tetragonolobus lectin I (PTL-I) and Griffonia simplicifolia lectin II (GSL-II), in particular at least two lectins selected from MAH-II, EEL, PTL-I and GSL-II, in particular the two lectins MAH-II and EEL, in order to obtain cancer stem cells of labeled hormone-dependent cancer target organs in a biological sample.

Abstract: A method for the radiographic imaging of a three-dimensional internal structure which forms part of an object located within a field of view, a radiographic image processing device and a radiographic imaging device, which are particularly suitable for locating a characteristic point of an internal structure on a radiographic image.

Abstract: A method for detecting and counting the microorganisms in a sample is described. The method comprises: a) selectively enriching the microorganism sought in the sample, b) inducing or activating at least one enzymatic activity of the microorganism, c) immunomagnetically concentrating the microorganism, d) fluorescently labeling the microorganism, and e) detecting and analyzing the fluorescence making possible the numeration or counting of the microorganisms sought by flow cytometry, filtration cytometry or fluorescence microscopy.

Abstract: A Yeast Artificial Chromosome (YAC) directing the expression of one or more activities of the humanized glycosylation pathway is provided. The said YAC comprises one or more expression cassettes for fusion proteins of heterologous glycosylation pathway and an ER/Golgi retention sequence. The invention also relates to new yeast cells which contain the said YAC. Finally, the invention also provides a method for producing recombinant target glycoproteins.

Abstract: The present application relates to genetically modified yeasts for the production of glycoproteins having optimized and homogeneous glycan structures. These yeasts comprise an inactivation of the Och 1 gene, the integration by homologous recombination, into an auxotrophic marker, of an expression cassette comprising a first promoter, and an open reading frame comprising the coding sequence for an ?-1,2-mannosidase I, and the integration of a cassette comprising a second promoter different from said first promoter and the coding sequence for an exogenous glycoprotein. These yeasts make it possible to produce EPO with an optimized and 98% homogeneous glycosylation.

Abstract: The present application relates to genetically modified yeasts for the production of glycoproteins having optimized and homogeneous glycan structures. These yeasts comprise an inactivation of the Och 1 gene, the integration by homologous recombination, into an auxotrophic marker, of an expression cassette comprising a first promoter, and an open reading frame comprising the coding sequence for an ?-1,2-mannosidase I, and the integration of a cassette comprising a second promoter different from said first promoter and the coding sequence for an exogenous glycoprotein. These yeasts make it possible to produce EPO with an optimized and 98% homogeneous glycosylation.

Abstract: The invention concerns a method for detecting and counting micro-organisms in a sample comprising the following steps: (a) selectively enriching the micro-organism sought in the sample, (b) conditioning said micro-organism, (c) immunomagnetic concentration of the conditioned microorganism, (d) fluorescent marking of the concentrated micro-organism, and (e) detecting and analyzing the fluorescence.