Patents by Inventor Vincent Divino
Vincent Divino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20040106940Abstract: Methods and devices for treating diseases and conditions that change the spacial relationship between the vertebral bodies and the intervertebral disks, or that cause instability of the vertebral column, or both, and a method and devices that allow the surgeon to access the intervertebral space to restore a more normal three-dimensional configuration of the space, with or without additionally fusing two adjacent vertebrae.Type: ApplicationFiled: June 25, 2003Publication date: June 3, 2004Inventors: Samuel M. Shaolian, George P. Teitelbaum, Vincent Divino, Michael R. Henson
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Publication number: 20040092993Abstract: Methods and devices for treating diseases and conditions that change the spacial relationship between the vertebral bodies and the intervertebral disks, or that cause instability of the vertebral column, or both, and a method and devices that allow the surgeon to access the intervertebral space to restore a more normal three-dimensional configuration of the space, with or without additionally fusing two adjacent vertebrae.Type: ApplicationFiled: April 22, 2003Publication date: May 13, 2004Inventors: George P. Teitelbaum, Samuel M. Shaolian, Thanh Van Nguyen, Frank Nguyen, To V. Pham, Vincent Divino, Michael R. Henson
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Publication number: 20040092933Abstract: Methods and devices for treating diseases and conditions that change the spacial relationship between the vertebral bodies and the intervertebral disks, or that cause instability of the vertebral column, or both, and a method and devices that allow the surgeon to access the intervertebral space to restore a more normal three-dimensional configuration of the space, with or without additionally fusing two adjacent vertebrae.Type: ApplicationFiled: June 25, 2003Publication date: May 13, 2004Inventors: Samuel M. Shaolian, George P. Teitelbaum, Thanh Van Nguyen, Frank Nguyen, To V. Pham, Vincent Divino, Michael R. Henson
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Publication number: 20040019319Abstract: A system utilizes an oxygenation device to generate a gas-enriched physiologic fluid and to combine it with a bodily fluid to create a gas-enriched bodily fluid. The oxygenation device may take the form of a disposable cartridge, which is placed within an enclosure. An electronic controller manages various aspects of the system, such as the production of gas-enriched fluids, flow rates, bubble detection, and automatic operation and shut down.Type: ApplicationFiled: October 24, 2002Publication date: January 29, 2004Inventors: Daw J. Derek, William R. Patterson, Stephen E. Myrick, Jeffrey L. Creech, Vincent Divino, Gregory P. Watson, Paul J. Zalesky
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Patent number: 6676900Abstract: A gas-enriched fluid is provided by the combination of a first fluid, such as a patient's blood, with a second gas-supersaturated fluid, such as an oxygen supersaturated fluid. In this example, a catheter assembly includes a portion that receives the patient's blood from a pump and that receives the oxygen supersaturated fluid from an appropriate fluid source. The oxygen supersaturated fluid is advantageously combined with the blood in an area of laminar flow, and then this gas-enriched fluid is delivered to the patient through an appropriate lumen coupled to the portion of the catheter assembly.Type: GrantFiled: October 30, 2000Date of Patent: January 13, 2004Assignees: TherOx, Inc., Wayne State UniversityInventors: Vincent Divino, Jr., Seth A. Foerster, James M. Gessert, Robert A. Mest, Paul J. Zalesky, James Richard Spears
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Publication number: 20030215356Abstract: An apparatus and method for blood oxygenation is provided, advantageously comprising an extracorporeal circuit for the preparation and delivery of hyperoxic or hyperbaric blood. In one embodiment, an apparatus for gas-supersaturating fluids, e.g., physiologic saline, includes a chamber having a first inlet to receive the fluid; a second inlet to receive a gas, e.g., oxygen, from a gas supply that maintains pressure within the chamber at a predetermined level, advantageously about 600 p.s.i.; and an outlet advantageously coupled to a capillary assembly. An atomizer nozzle coupled to the first inlet advantageously creates within the chamber fine droplets of fluid into which gas diffuses to create the gas-supersaturated fluid, which collects within the chamber below the atomizer nozzle for removal via the outlet.Type: ApplicationFiled: March 7, 2003Publication date: November 20, 2003Inventors: William R. Patterson, Stephen E. Myrick, Vincent Divino, Jeffrey L. Creech, Mark S. Buhr
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Publication number: 20030194348Abstract: An apparatus and method for blood oxygenation is provided, advantageously comprising an extracorporeal circuit for the preparation and delivery of hyperoxic or hyperbaric blood. In one embodiment, an apparatus for gas-supersaturating fluids, e.g., physiologic saline, includes a chamber having a first inlet to receive the fluid; a second inlet to receive a gas, e.g., oxygen, from a gas supply that maintains pressure within the chamber at a predetermined level, advantageously about 600 p.s.i.; and an outlet advantageously coupled to a capillary assembly. An atomizer nozzle coupled to the first inlet advantageously creates within the chamber fine droplets of fluid into which gas diffuses to create the gas-supersaturated fluid, which collects within the chamber below the atomizer nozzle for removal via the outlet.Type: ApplicationFiled: April 25, 2003Publication date: October 16, 2003Inventors: Vincent Divino, Jeffrey L. Creech, William R. Patterson, Stephen E. Myrick
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Patent number: 6602467Abstract: An apparatus and method for blood oxygenation are provided. The apparatus advantageously comprises a liquid-to-liquid oxygenation assembly. The liquid-to-liquid oxygenation assembly includes a pressurizable chamber having inlets for a first gas-supersaturated fluid and a second fluid, such as blood. The inlets are advantageously positioned on the mixing chamber in such a way that the first fluid and the second fluid enter the mixing chamber normally to each other to promote mixing and liquid-to-liquid gas transfer. The mixed fluid exits the chamber via an outlet for delivery to a patient.Type: GrantFiled: September 30, 1999Date of Patent: August 5, 2003Assignee: TherOx, Inc.Inventors: Vincent Divino, Jr., William R. Patterson, Jeffrey L. Creech, Stephen E. Myrick
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Patent number: 6596235Abstract: An apparatus and method for blood oxygenation is provided, advantageously comprising an extracorporeal circuit for the preparation and delivery of hyperoxic or hyperbaric blood. In one embodiment, an apparatus for gas-supersaturating fluids, e.g., physiologic saline, includes a chamber having a first inlet to receive the fluid; a second inlet to receive a gas, e.g., oxygen, from a gas supply that maintains pressure within the chamber at a predetermined level, advantageously about 600 p.s.i.; and an outlet advantageously coupled to a capillary assembly. An atomizer nozzle coupled to the first inlet advantageously creates within the chamber fine droplets of fluid into which gas diffuses to create the gas-supersaturated fluid, which collects within the chamber below the atomizer nozzle for removal via the outlet.Type: GrantFiled: February 7, 2001Date of Patent: July 22, 2003Assignee: TherOx, Inc.Inventors: Vincent Divino, Jr., Paul J. Zalesky, William R. Patterson
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Patent number: 6582387Abstract: A system utilizes an oxygenation device to generate a gas-enriched physiologic fluid and to combine it with a bodily fluid to create a gas-enriched bodily fluid. The oxygenation device may take the form of a disposable cartridge, which is placed within an enclosure. An electronic controller manages various aspects of the system, such as the production of gas-enriched fluids, flow rates, bubble detection, and automatic operation and shut down.Type: GrantFiled: March 20, 2001Date of Patent: June 24, 2003Assignee: TherOx, Inc.Inventors: Daw J. Derek, William R. Patterson, Stephen E. Myrick, Jeffrey L. Creech, Vincent Divino, Jr., Gregory P. Watson, Paul J. Zalesky
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Publication number: 20030095892Abstract: Apparatus and method for blood oxygenation are provided. The apparatus includes a chamber having a first inlet to receive a fluid, e.g., physiologic saline; a second inlet to receive a gas, e.g., oxygen, from a gas supply; and an outlet coupled to a capillary assembly. An atomizer nozzle coupled to the first inlet creates within the chamber fine droplets of fluid into which the gas diffuses to create a gas-supersaturated fluid, which is removed via the outlet. The removed gas-supersaturated fluid mixes with blood within a liquid-to-liquid oxygenation assembly to form oxygenated blood for delivery to a patient. Alternately, the blood may be provided by a pump to a high pressure hollow fiber or other type membrane oxygenator within which oxygen diffuses across the membrane(s) and into the blood to form oxygenated blood, again for delivery to a patient or other site.Type: ApplicationFiled: February 8, 2002Publication date: May 22, 2003Inventors: William R. Patterson, Stephen E. Myrick, Vincent Divino, Jeffrey L. Creech, Mark S. Buhr
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Patent number: 6565807Abstract: An apparatus and method for blood oxygenation are provided. The apparatus includes a chamber having a first inlet to receive a gas-supersaturating fluid, e.g., physiologic saline; a second inlet to receive a gas, e.g., oxygen, from a gas supply; and an outlet coupled to a capillary assembly. An atomizer nozzle coupled to the first inlet creates within the chamber fine droplets of fluid into which the gas diffuses to create the gas-supersaturated fluid, which is removed via the outlet. The removed gas-supersaturated fluid mixes with blood within a liquid-to-liquid oxygenation assembly to form oxygenated blood for delivery to a patient. Alternately, the blood may be provided by the pump to a high pressure hollow fiber or other type membrane oxygenator within which oxygen diffuses across the membrane(s) and into the blood to form oxygenated blood, again for delivery to a patient or other site.Type: GrantFiled: December 21, 1999Date of Patent: May 20, 2003Assignee: TherOx, Inc.Inventors: William R. Patterson, Stephen E. Myrick, Vincent Divino, Jr., Jeffrey L. Creech, Mark S. Buhr
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Patent number: 6558502Abstract: The present invention is a device for insertion into a human or animal body, in a preferred embodiment a perfusion guidewire capable of delivering perfusion fluids to a vascular site while at the same time exhibiting handling characteristics associated with existing non-perfusion guidewires. Preferred embodiments include a perfusion guidewire which closely matches the dimensions and physical characteristics of standard guidewires. Preferred embodiments also permit high pressure perfusion of oxygen-supersaturated solutions, and include a diffuser segment which divides the flow and reduces fluid velocity, thereby providing an atraumatic, non-cavitating, bubble-free delivery to the patient. The invention also encompasses the attachment of a core wire within a tubular housing to provide superior characteristics to such guidewires, balloon catheters and similar devices.Type: GrantFiled: May 16, 2001Date of Patent: May 6, 2003Assignee: TherOx, Inc.Inventors: Vincent Divino, Jr., John Merritt, Seth A. Foerster, William C. Homet, Paul J. Zalesky
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Publication number: 20020192111Abstract: A gas-enriched fluid is provided by the combination of a first fluid, such as a patient's blood, with a second gas-supersaturated fluid, such as an oxygen supersaturated fluid. In this example, a catheter assembly includes a portion that receives the patient's blood from a pump and that receives the oxygen supersaturated fluid from an appropriate fluid source. The oxygen supersaturated fluid is advantageously combined with the blood in an area of laminar flow, and then this gas-enriched fluid is delivered to the patient through an appropriate lumen coupled to the portion of the catheter assembly.Type: ApplicationFiled: August 6, 2002Publication date: December 19, 2002Inventors: Vincent Divino, Seth A. Foerster, James M. Gessert, Robert A. Mest, Paul J. Zalesky
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Publication number: 20020138034Abstract: A system utilizes an oxygenation device to generate a gas-enriched physiologic fluid and to combine it with a bodily fluid to create a gas-enriched bodily fluid. The oxygenation device may take the form of a disposable cartridge, which is placed within an enclosure. An electronic controller manages various aspects of the system, such as the production of gas-enriched fluids, flow rates, bubble detection, and automatic operation and shut down.Type: ApplicationFiled: March 20, 2001Publication date: September 26, 2002Inventors: Daw J. Derek, William R. Patterson, Stephen E. Myrick, Jeffrey L. Creech, Vincent Divino, Gregory P. Watson, Paul J. Zalesky
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Patent number: 6454997Abstract: A gas-enriched fluid is provided by the combination of a first fluid, such as a patient's blood, with a second gas-supersaturated fluid, such as an oxygen supersaturated fluid. In this example, a catheter assembly includes a portion that receives the patient's blood from a pump and that receives the oxygen supersaturated fluid from an appropriate fluid source. The oxygen supersaturated fluid is advantageously combined with the blood in an area of laminar flow, and then this gas-enriched fluid is delivered to the patient through an appropriate lumen coupled to the portion of the catheter assembly.Type: GrantFiled: July 24, 1998Date of Patent: September 24, 2002Assignee: TherOx, Inc.Inventors: Vincent Divino, Jr., Seth A. Foerster, James M. Gessert, Robert A. Mest, Paul J. Zalesky
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Patent number: 6387324Abstract: An apparatus and method for blood oxygenation is provided, advantageously comprising an extracorporeal circuit for the preparation and delivery of hyperoxic or hyperbaric blood. In one embodiment, an apparatus for gas-supersaturating fluids, e.g., physiologic saline, includes a chamber having a first inlet to receive the fluid; a second inlet to receive a gas, e.g., oxygen, from a gas supply that maintains pressure within the chamber at a predetermined level, advantageously about 600 p.s.i.; and an outlet advantageously coupled to a capillary assembly. An atomizer nozzle coupled to the first inlet advantageously creates within the chamber fine droplets of fluid into which gas diffuses to create the gas-supersaturated fluid, which collects within the chamber below the atomizer nozzle for removal via the outlet.Type: GrantFiled: September 30, 1999Date of Patent: May 14, 2002Assignee: TherOx, Inc.Inventors: William R. Patterson, Stephen E. Myrick, Vincent Divino, Jr., Jeffrey L. Creech, Mark S. Buhr
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Publication number: 20020040232Abstract: The present invention is a device for insertion into a human or animal body, in a preferred embodiment a perfusion guidewire capable of delivering perfusion fluids to a vascular site while at the same time exhibiting handling characteristics associated with existing non-perfusion guidewires. Preferred embodiments include a perfusion guidewire which closely matches the dimensions and physical characteristics of standard guidewires. Preferred embodiments also permit high pressure perfusion of oxygen-supersaturated solutions, and include a diffuser segment which divides the flow and reduces fluid velocity, thereby providing an a traumatic, non-cavitating, bubble-free delivery to the patient. The invention also encompasses the attachment of a core wire within a tubular housing to provide superior characteristics to such guidewires, balloon catheters and similar devices.Type: ApplicationFiled: May 16, 2001Publication date: April 4, 2002Inventors: Vincent Divino, Jr., John Merritt, Seth A. Foerster, William C. Homet, Paul J. Zalesky
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Publication number: 20010016729Abstract: An apparatus and method for blood oxygenation is provided, advantageously comprising an extracorporeal circuit for the preparation and delivery of hyperoxic or hyperbaric blood. In one embodiment, an apparatus for gas-supersaturating fluids, e.g., physiologic saline, includes a chamber having a first inlet to receive the fluid; a second inlet to receive a gas, e.g., oxygen, from a gas supply that maintains pressure within the chamber at a predetermined level, advantageously about 600 p.s.i.; and an outlet advantageously coupled to a capillary assembly. An atomizer nozzle coupled to the first inlet advantageously creates within the chamber fine droplets of fluid into which gas diffuses to create the gas-supersaturated fluid, which collects within the chamber below the atomizer nozzle for removal via the outlet.Type: ApplicationFiled: February 7, 2001Publication date: August 23, 2001Inventors: Vincent Divino, Paul J. Zalesky, William R. Patterson
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Patent number: 6235007Abstract: The present invention is a device for insertion into a human or animal body, in a preferred embodiment a perfusion guidewire capable of delivering perfusion fluids to a vascular site while at the same time exhibiting handling characteristics associated with existing non-perfusion guidewires. Preferred embodiments include a perfusion guidewire which closely matches the dimensions and physical characteristics of standard guidewires. Preferred embodiments also permit high pressure perfusion of oxygen-supersaturated solutions, and include a diffuser segment which divides the flow and reduces fluid velocity, thereby providing an atraumatic, non-cavitating, bubble-free delivery to the patient. The invention also encompasses the attachment of a core wire within a tubular housing to provide superior characteristics to such guidewires, balloon catheters and similar devices.Type: GrantFiled: June 5, 1998Date of Patent: May 22, 2001Assignee: TherOx, Inc.Inventors: Vincent Divino, Jr., John Merritt, Seth A. Foerster, William C. Homet, Paul J. Zalesky