Abstract: Medical devices and methods for making and using the same are disclosed. An example medical device may include a guidewire. The guidewire may include a core wire having a distal portion. A tubular member may be disposed over the distal portion. The tubular member may have a plurality of slots formed therein and may have a longitudinal axis. The tubular member may include a variably spaced slot section that has a flexural rigidity that varies from a first flexural rigidity to a second flexural rigidity. The transition from the first flexural rigidity to the second flexural rigidity may be a function of a fourth power equation. The first flexural rigidity may be in the range of about 1×10?6 to about 9×10?5 lbs-inches2. The second flexural rigidity may be in the range of about 1×10?3 to about 5×10?3 lbs-inches2.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device includes a pressure sensing guidewire. The pressure sensing guidewire may include an elongate shaft including a core wire having a distal portion and a coil disposed over the distal portion. A pressure sensor may be disposed along the distal portion of the core wire and within the coil. One or more leads may be coupled to the pressure sensor. An opening may be formed in the coil that provides access to the pressure sensor.

Abstract: Medical devices and methods for making and using the same are disclosed. An example medical device may include a guidewire. The guidewire may include a core wire having a distal portion. A tubular member may be disposed over the distal portion. The tubular member may have a plurality of slots formed therein and may have a longitudinal axis. The tubular member may include a variably spaced slot section that has a flexural rigidity that varies from a first flexural rigidity to a second flexural rigidity. The transition from the first flexural rigidity to the second flexural rigidity may be a function of a fourth power equation. The first flexural rigidity may be in the range of about 1×10?6 to about 9×10?5 lbs-inches2. The second flexural rigidity may be in the range of about 1×10?3 to about 5×10?3 lbs-inches2.

Abstract: Medical devices and methods for making and using the same are disclosed. An example medical device may include a guidewire. The guidewire may include a core wire having a distal portion. A tubular member may be disposed over the distal portion. The tubular member may have a plurality of slots formed therein and may have a longitudinal axis. The tubular member may include a variably spaced slot section that has a flexural rigidity that varies from a first flexural rigidity to a second flexural rigidity. The transition from the first flexural rigidity to the second flexural rigidity may be a function of a fourth power equation. The first flexural rigidity may be in the range of about 1×10?6 to about 9×10?5 lbs-inches2. The second flexural rigidity may be in the range of about 1×10?3 to about 5×10?3 lbs-inches2.

Abstract: Alternative designs, materials and manufacturing methods for guidewires. Some embodiments pertain to a composite guidewire having proximal and distal section, and a connector adapted and configured for permanently joining the proximal section to the distal section. In some embodiments, at least one of the sections is made of a linear-elastic nickel-titanium alloy. Several alternative guidewire tip constructions and/or designs including methods and techniques of construction are also disclosed.

Abstract: An elongate medical device such as a guidewire, that may comprise a first elongate member having a proximal end, a distal end and a lumen there between, a second elongate member having a proximal end and a distal end, the second elongate member at least partially disposed in the first elongate member, a first connection between first elongate member and the second elongate member at the proximal end of the first elongate member, a second connection between the first elongate member and the second elongate member at the distal end of the first elongate member, and a third connection between the first elongate member and the second elongate member, the third connection disposed at a point between the first connection and the second connection, wherein the third connection is substantially at a location selected by the Method for Enhancing the Ratio of Torsional Stiffness to Transverse Flexibility.

Abstract: Medical devices and methods for making and using the same are disclosed. An example medical device may include a guidewire. The guidewire may include a core wire having a distal portion. A tubular member may be disposed over the distal portion. The tubular member may have a plurality of slots formed therein and may have a longitudinal axis. The tubular member may include a variably spaced slot section that has a flexural rigidity that varies from a first flexural rigidity to a second flexural rigidity. The transition from the first flexural rigidity to the second flexural rigidity may be a function of a fourth power equation. The first flexural rigidity may be in the range of about 1×10?6 to about 9×10?5 lbs-inches2. The second flexural rigidity may be in the range of about 1×10?3 to about 5×10?3 lbs-inches2.

Abstract: Medical devices and methods for making and using the same. An example of medical devices includes a core member and a tubular member disposed over a portion of the core member. The core member may include an outer diameter region that has an outside diameter that is substantially the same as the inside diameter of the tubular member so that the core member can be attached to the tubular member. The medical device may also include a coil that is coupled to the tubular member.

Abstract: An elongate medical device such as a guidewire, that may comprise a first elongate member having a proximal end, a distal end and a lumen there between, a second elongate member having a proximal end and a distal end, the second elongate member at least partially disposed in the first elongate member, a first connection between first elongate member and the second elongate member at the proximal end of the first elongate member, a second connection between the first elongate member and the second elongate member at the distal end of the first elongate member, and a third connection between the first elongate member and the second elongate member, the third connection disposed at a point between the first connection and the second connection, wherein the third connection is substantially at a location selected by the Method for Enhancing the Ratio of Torsional Stiffness to Transverse Flexibility.

Abstract: Alternative designs, materials and manufacturing methods for guidewires. Some embodiments pertain to a composite guidewire having proximal and distal section, and a connector adapted and configured for permanently joining the proximal section to the distal section. In some embodiments, at least one of the sections is made of a linear-elastic nickel-titanium alloy. Several alternative guidewire tip constructions and/or designs including methods and techniques of construction are also disclosed.

Abstract: Alternative designs, materials and manufacturing methods for guidewires. Some embodiments pertain to a composite guidewire having proximal and distal section, and a connector adapted and configured for permanently joining the proximal section to the distal section. In some embodiments, at least one of the sections is made of a linear-elastic nickel-titanium alloy. Several alternative guidewire tip constructions and/or designs including methods and techniques of construction are also disclosed.

Abstract: Alternative designs, materials and manufacturing methods for guidewires. Some embodiments pertain to a composite guidewire having proximal and distal section, and a connector adapted and configured for permanently joining the proximal section to the distal section. In some embodiments, at least one of the sections is made of a linear-elastic nickel-titanium alloy. Several alternative guidewire tip constructions and/or designs including methods and techniques of construction are also disclosed.

Abstract: Alternative designs, materials and manufacturing methods for guidewires. Some embodiments pertain to a composite guidewire having proximal and distal section, and a connector adapted and configured for permanently joining the proximal section to the distal section. In some embodiments, at least one of the sections is made of a linear-elastic nickel-titanium alloy. Several alternative guidewire tip constructions and/or designs including methods and techniques of construction are also disclosed.

Abstract: A canister for launching a missile having a cylindrical outer tube with a hemispherical head releaseably secured to its lower end connected through stiffeners to an inner tubular member to form a passage for the gases generated when the missile is fired. A restraint mechanism secures the missile to a base plate, which is itself mounted on shock absorbers, with a release mechanism responsive to the firing of the missile for disabling the restraint mechanism.