Patents by Inventor Virginia I. Roxas-Duncan

Virginia I. Roxas-Duncan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SMALL MOLECULE INHIBITORS OF BOTULINUM NEUROTOXINS
    Publication number: 20190256471
    Abstract: The invention provides potent quinolinol-based BoNT/A small-molecule inhibitors of botulinum neurotoxins, in particular of Clostridium botulinum serotype A neurotoxins. The invention also provides methods of using these small-molecule inhibitors to inhibit infections by Clostridium botulinum, as well as, methods of preventing infections by Clostridium botulinum through materials that may be ingested.
    Type: Application
    Filed: May 3, 2019
    Publication date: August 22, 2019
    Applicant: THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AR
    Inventors: VIRGINIA I. ROXAS-DUNCAN, LEONARD A. SMITH, NIZAMETTIN GUL, JOHN H. CARDELLINA, II, REBECCA C. VIEIRA, SUSAN M. ENSEL, DAVID C.H. YANG, ISTVAN J. ENYEDY, SIVANESAN DAKSHANAMURTHY, SALIMUDDIN SHAH
  • Small molecule inhibitors of botulinum neurotoxins
    Patent number: 10301265
    Abstract: The invention provides potent quinolinol-based BoNT/A small-molecule inhibitors of botulinum neurotoxins, in particular of Clostridium botulinum serotype A neurotoxins. The invention also provides methods of using these small-molecule inhibitors to inhibit infections by Clostridium botulinum, as well as, methods of preventing infections by Clostridium botulinum through materials that may be ingested.
    Type: Grant
    Filed: May 28, 2009
    Date of Patent: May 28, 2019
    Inventors: Virginia I. Roxas-Duncan, Leonard A. Smith, Nizamettin Gul, John H. Cardellina, II, Rebecca C. Vieira, Susan M. Ensel, David C. H. Yang, Istvan J. Enyedy, Sivanesan Dakshanamurthy, Salimuddin Shah
  • SMALL MOLECULE INHIBITORS OF BOTULINUM NEUROTOXINS
    Publication number: 20110294848
    Abstract: The invention provides potent quinolinol-based BoNT/A small-molecule inhibitors of botulinum neurotoxins, in particular of Clostridium botulinum serotype A neurotoxins. The invention also provides methods of using these small-molecule inhibitors to inhibit infections by Clostridium botulinum, as well as, methods of preventing infections by Clostridium botulinum through materials that may be ingested.
    Type: Application
    Filed: May 28, 2009
    Publication date: December 1, 2011
    Inventors: Virginia I. Roxas-Duncan, Leonard A. Smith, Nizamettin Gul, John H. Cardellina, II, Rebecca C. Vieira, Susan M. Ensel, David C.H. Yang, Istvan J. Enyedy, Sivanesan Darkshanamurthy, Salimuddin Shah