Patents by Inventor Vish Koppaka

Vish Koppaka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MANUFACTURE OF ACTIVE HIGHLY PHOSPHORYLATED HUMAN LYSOSOMAL SULFATASE ENZYMES AND USES THEREOF
    Publication number: 20210189357
    Abstract: This invention provides compositions of active highly phosphorylated lysosomal sulfatase enzymes, their pharmaceutical compositions, methods of producing and purifying such lysosomal sulfatase enzymes and compositions and their use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the lysosomal sulfatase enzyme.
    Type: Application
    Filed: March 1, 2021
    Publication date: June 24, 2021
    Inventors: Erno Pungor, Charles Hague, Zhi Chen, Melita Dvorak-Ewell, Michel Claude Vellard, Vish Koppaka
  • Manufacture of active highly phosphorylated human lysosomal sulfatase enzymes and uses thereof
    Patent number: 10934534
    Abstract: This invention provides compositions of active highly phosphorylated lysosomal sulfatase enzymes, their pharmaceutical compositions, methods of producing and purifying such lysosomal sulfatase enzymes and compositions and their use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the lysosomal sulfatase enzyme.
    Type: Grant
    Filed: February 6, 2020
    Date of Patent: March 2, 2021
    Assignee: BIOMARIN PHARMACEUTICAL INC.
    Inventors: Erno Pungor, Charles Hague, Zhi Chen, Melita Dvorak-Ewell, Michel Claude Vellard, Vish Koppaka
  • Manufacture of Active Highly Phosphorylated Human Lysosomal Sulfatase Enzymes and Uses Thereof
    Publication number: 20200181590
    Abstract: This invention provides compositions of active highly phosphorylated lysosomal sulfatase enzymes, their pharmaceutical compositions, methods of producing and purifying such lysosomal sulfatase enzymes and compositions and their use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the lysosomal sulfatase enzyme.
    Type: Application
    Filed: February 6, 2020
    Publication date: June 11, 2020
    Inventors: Erno Pungor, Charles Hague, Zhi Chen, Melita Dvorak-Ewell, Michel Claude Vellard, Vish Koppaka
  • Manufacture of active highly phosphorylated human N-acetylgalactosamine-6-sulfatase and uses thereof
    Patent number: 9567572
    Abstract: This invention provides compositions of active highly phosphorylated human N-acetylgalactosamine-6-sulfatase (GALNS), and pharmaceutical compositions and formulations thereof, methods of producing and purifying GALNS, and its use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the GALNS enzyme, e.g., Mucopolysaccharidosis IVa (MPS IVa or Morquio A syndrome).
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: February 14, 2017
    Assignee: BioMarin Pharmaceutical Inc.
    Inventors: Vish Koppaka, Michel Claude Vellard, Augustus O. Okhamafe, Kidisti Araya
  • Manufacture of Active Highly Phosphorylated Human N-Acetylgalactosamine-6-Sulfatase and Uses Thereof
    Publication number: 20160186149
    Abstract: This invention provides compositions of active highly phosphorylated human N-acetylgalactosamine-6-sulfatase (GALNS), and pharmaceutical compositions and formulations thereof, methods of producing and purifying GALNS, and its use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the GALNS enzyme, e.g., Mucopolysaccharidosis IVa (MPS IVa or Morquio A syndrome).
    Type: Application
    Filed: December 17, 2014
    Publication date: June 30, 2016
    Inventors: Vish Koppaka, Michel Claude Vellard, Augustus O. Okhamafe, Kidisti Araya
  • Manufacture of active highly phosphorylated human N-acetylgalactosamine-6-sulfatase and uses thereof
    Patent number: 8940513
    Abstract: This invention provides compositions of active highly phosphorylated human N-acetylgalactosamine-6-sulfatase (GALNS), and pharmaceutical compositions and formulations thereof, methods of producing and purifying GALNS, and its use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the GALNS enzyme, e.g., Mucopolysaccharidosis IVa (MPS IVa or Morquio A syndrome).
    Type: Grant
    Filed: May 19, 2014
    Date of Patent: January 27, 2015
    Assignee: BioMarin Pharmaceutical Inc.
    Inventors: Vish Koppaka, Michel Claude Vellard, Augustus Okhamafe, Kidisti Araya
  • MANUFACTURE OF ACTIVE HIGHLY PHOSPHORYLATED HUMAN N-ACETYLGALACTOSAMINE-6-SULFATASE AND USES THEREOF
    Publication number: 20140341878
    Abstract: This invention provides compositions of active highly phosphorylated human N-acetylgalactosamine-6-sulfatase (GALNS), and pharmaceutical compositions and formulations thereof, methods of producing and purifying GALNS, and its use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the GALNS enzyme, e.g., Mucopolysaccharidosis IVa (MPS IVa or Morquio A syndrome).
    Type: Application
    Filed: May 19, 2014
    Publication date: November 20, 2014
    Applicant: BioMarin Pharmaceutical Inc.
    Inventors: Vish Koppaka, Michel Claude Vellard, Augustus Okhamafe, Kidisti Araya
  • Manufacture of active highly phosphorylated human N-acetylgalactosamine-6-sulfatase and uses thereof
    Patent number: 8765437
    Abstract: This invention provides compositions of active highly phosphorylated human N-acetylgalactosamine-6-sulfatase (GALNS), and pharmaceutical compositions and formulations thereof, methods of producing and purifying GALNS, and its use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the GALNS enzyme, e.g., Mucopolysaccharidosis IVa (MPS IVa or Morquio A syndrome).
    Type: Grant
    Filed: July 22, 2011
    Date of Patent: July 1, 2014
    Assignee: Biomarin Pharmaceutical Inc.
    Inventors: Vish Koppaka, Michel Claude Vellard, Augustus O. Okhamafe, Kidisti Araya
  • MANUFACTURE OF ACTIVE HIGHLY PHOSPHORYLATED HUMAN LYSOSOMAL SULFATASE ENZYMES AND USES THEREOF
    Publication number: 20120208221
    Abstract: This invention provides compositions of active highly phosphorylated lysosomal sulfatase enzymes, their pharmaceutical compositions, methods of producing and purifying such lysosomal sulfatase enzymes and compositions and their use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the lysosomal sulfatase enzyme.
    Type: Application
    Filed: February 10, 2012
    Publication date: August 16, 2012
    Applicant: BIOMARIN PHARMACEUTICAL INC.
    Inventors: Michel C. Vellard, Vish Koppaka, Melita Dvorak-Ewell, Erno Pungor, Charles Hague
  • MANUFACTURE OF ACTIVE HIGHLY PHOSPHORYLATED HUMAN N-ACETYLGALACTOSAMINE-6-SULFATASE AND USES THEREOF
    Publication number: 20120189605
    Abstract: This invention provides compositions of active highly phosphorylated human N-acetylgalactosamine-6-sulfatase (GALNS), and pharmaceutical compositions and formulations thereof, methods of producing and purifying GALNS, and its use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the GALNS enzyme, e.g., Mucopolysaccharidosis IVa (MPS IVa or Morquio A syndrome).
    Type: Application
    Filed: July 22, 2011
    Publication date: July 26, 2012
    Applicant: BIOMARIN PHARMACEUTICAL INC.
    Inventors: Vish Koppaka, Michel C. Vellard, Augustus O. Okhamafe, Kidisti Araya
  • Manufacture of active highly phosphorylated human lysosomal sulfatase enzymes and uses thereof
    Patent number: 8128925
    Abstract: This invention provides compositions of active highly phosphorylated lysosomal sulfatase enzymes, their pharmaceutical compositions, methods of producing and purifying such lysosomal sulfatase enzymes and compositions and their use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the lysosomal sulfatase enzyme.
    Type: Grant
    Filed: January 16, 2009
    Date of Patent: March 6, 2012
    Assignee: Biomarin Pharmaceutical Inc.
    Inventors: Michel Claude Vellard, Vish Koppaka, Melita Dvorak-Ewell, Erno Pungor, Charles Hague
  • Manufacture of active highly phosphorylated human lysosomal sulfatase enzymes and uses thereof
    Patent number: 7722865
    Abstract: This invention provides compositions of active highly phosphorylated lysosomal sulfatase enzymes, their pharmaceutical compositions, methods of producing and purifying such lysosomal sulfatase enzymes and compositions and their use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the lysosomal sulfatase enzyme.
    Type: Grant
    Filed: December 1, 2009
    Date of Patent: May 25, 2010
    Assignee: Biomarin Pharmaceutical Inc.
    Inventors: Michel Claude Vellard, Vish Koppaka
  • Manufacture of Active Highly Phosphorylated Human Lysosomal Sulfatase Enzymes and Uses Thereof
    Publication number: 20100068195
    Abstract: This invention provides compositions of active highly phosphorylated lysosomal sulfatase enzymes, their pharmaceutical compositions, methods of producing and purifying such lysosomal sulfatase enzymes and compositions and their use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the lysosomal sulfatase enzyme.
    Type: Application
    Filed: December 1, 2009
    Publication date: March 18, 2010
    Applicant: BIOMARIN PHARMACEUTICAL INC.
    Inventors: MICHEL C. VELLARD, VISH KOPPAKA
  • Manufacture of Active Highly Phosphorylated Human Lysosomal Sulfatase Enzymes and Uses Thereof
    Publication number: 20090186011
    Abstract: This invention provides compositions of active highly phosphorylated lysosomal sulfatase enzymes, their pharmaceutical compositions, methods of producing and purifying such lysosomal sulfatase enzymes and compositions and their use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the lysosomal sulfatase enzyme.
    Type: Application
    Filed: January 16, 2009
    Publication date: July 23, 2009
    Applicant: BIOMARIN PHARMACEUTICAL INC.
    Inventors: Michel Claude Vellard, Vish Koppaka, Melita Dvorak-Ewell, Erno Pungor, Charles Hague