Patents by Inventor Vitaliy V. Nesterenko
Vitaliy V. Nesterenko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7264184Abstract: The invention provides methods for separating outer birch bark from inner birch bark. The invention also provides methods for isolating betulin; lupeol; betulinic acid; 9,10-epoxy-18-hydroxyoctadecanoic acid; 9,10,18-trihydroxyoctadecanoic acid; polyphenolic polymers and fatty acids from birch bark.Type: GrantFiled: October 14, 2004Date of Patent: September 4, 2007Assignee: Regents of the University of MinnesotaInventors: Pavel A. Krasutsky, Robert M. Carlson, Vitaliy V. Nesterenko, Igor V. Kolomitsyn, Chris F. Edwardson
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Patent number: 7198808Abstract: The present invention provides a method for selectively extracting acidic and/or non-acidic compounds from natural material such as plant tissue.Type: GrantFiled: May 9, 2003Date of Patent: April 3, 2007Assignee: Regents of the University of MinnesotaInventors: Pavel A. Krasutsky, Vitaliy V. Nesterenko
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Patent number: 6815553Abstract: The invention provides methods for separating outer birch bark from inner birch bark. The invention also provides methods for isolating betulin; lupeol; betulinic acid; 9,10-epoxy-18-hydroxyoctadecanoic acid; 9,10,18-trihydroxyoctadecanoic acid; polyphenolic polymers and fatty acids from birch bark.Type: GrantFiled: February 6, 2002Date of Patent: November 9, 2004Assignee: Regents of the University of MinnesotaInventors: Pavel A. Krasutsky, Robert M. Carlson, Vitaliy V. Nesterenko, Igor V. Kolomitsyn, Chris F. Edwardson
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Publication number: 20040009242Abstract: The present invention provides a method for selectively extracting acidic and/or non-acidic compounds from natural material such as plant tissue.Type: ApplicationFiled: May 9, 2003Publication date: January 15, 2004Applicant: Regents of the University of MinnesotaInventors: Pavel A. Krasutsky, Vitaliy V. Nesterenko
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Patent number: 6634575Abstract: The invention provides methods for separating outer birch bark from inner birch bark. The invention also provides methods for isolating betulin; lupeol; betulinic acid; 9,10-epoxy-18-hydroxyoctadecanoic acid; 9,10,18-trihydroxyoctadecanoic acid; polyphenolic polymers and fatty acids from birch bark.Type: GrantFiled: August 23, 2001Date of Patent: October 21, 2003Assignee: Regents of the University of MinnesotaInventors: Pavel A. Krasutsky, Robert M. Carlson, Vitaliy V. Nesterenko, Igor M. Kolomitsyn, Chris F. Edwardson
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Publication number: 20030073858Abstract: The present invention provides a method for preparing betulin-3-acetate including alcoholyzing betulin 3,28-dibenzoate; a process for preparing betulin-3-acetate including: (1) acylating betulin to provide betulin 3,28-dibenzoate and (2) alcoholyzing betulin 3,28-dibenzoate to provide betulin-3-acetate; and a process for preparing betulinic acid including: (1) acylating betulin to provide betulin 3,28-dibenzoate; (2) alcoholyzing betulin 3,28-dibenzoate to provide betulin-3-acetate; (3) oxidizing betulin-3-acetate to provide betulinic aldehyde-3-acetate; (4) oxidizing betulinic aldehyde-3-acetate to provide betulinic acid-3-acetate; and (5) deprotecting betulinic acid-3-acetate to provide betulinic acid.Type: ApplicationFiled: July 11, 2002Publication date: April 17, 2003Inventors: Pavel A. Krasutsky, Robert M. Carlson, Vitaliy V. Nesterenko
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Publication number: 20020155177Abstract: The present invention provides a method for selectively extracting acidic and/or non-acidic compounds from natural material such as plant tissue.Type: ApplicationFiled: January 17, 2002Publication date: October 24, 2002Inventors: Pavel A. Krasutsky, Vitaliy V. Nesterenko
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Publication number: 20020114853Abstract: The present invention provides a method for selectively extracting acidic and/or non-acidic compounds from natural material such as plant tissue.Type: ApplicationFiled: October 1, 2001Publication date: August 22, 2002Inventors: Pavel A. Krasutsky, Vitaliy V. Nesterenko
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Patent number: 6407270Abstract: The present invention provides a method for preparing an ester of betulin at the 3-position, e.g., betulin-3-acetate, including the selective alcoholysis of a betulin-3,28-diester, e.g., betulin-3,28-diacetate; a method for preparing betulin-3-acetate including (1) acetylating betulin to provide betulin-3,28-diacetate and (2) the alcoholysis of betulin-3,28-diacetate to provide betulin-3-acetate; a method for preparing betulinic acid from betulin-3-acetate including (1) acetylating betulin to provide betulin-3,28-diacetate, (2) the alcoholysis of betulin-3,28-diacetate to provide betulin-3-acetate, (3) oxidizing betulin-3-acetate to provide betulinic aldehyde-3-acetate, (4) oxidizing betulinic aldehyde-3-acetate to provide betulinic acid-3-acetate, and (5) deprotecting betulinic acid-3-acetate to provide betulinic acid.Type: GrantFiled: June 29, 2001Date of Patent: June 18, 2002Assignee: Regents of the University of MinnesotaInventors: Pavel A. Krasutsky, Robert M. Carlson, Vitaliy V. Nesterenko
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Publication number: 20020070167Abstract: The invention provides methods for separating outer birch bark from inner birch bark. The invention also provides methods for isolating betulin; lupeol; betulinic acid; 9,10-epoxy-18-hydroxyoctadecanoic acid; 9,10,18-trihydroxyoctadecanoic acid; polyphenolic polymers and fatty acids from birch bark.Type: ApplicationFiled: February 6, 2002Publication date: June 13, 2002Applicant: Regents of the University of MinnesotaInventors: Pavel A. Krasutsky, Robert M. Carlson, Vitaliy V. Nesterenko, Igor V. Kolomitsyn, Chris F. Edwardson
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Patent number: 6392070Abstract: The invention provides methods for separating outer birch bark from inner birch bark. The invention also provides methods for isolating betulin; lupeol; betulinic acid; 9,10-epoxy-18-hydroxyoctadecanoic acid; 9,10,18-trihydroxyoctadecanoic acid; polyphenolic polymers and fatty acids from birch bark.Type: GrantFiled: August 10, 1999Date of Patent: May 21, 2002Assignee: Regents of the University of MinnesotaInventors: Pavel A. Krasutsky, Robert M. Carlson, Vitaliy V. Nesterenko
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Publication number: 20020043577Abstract: The invention provides methods for separating outer birch bark from inner birch bark. The invention also provides methods for isolating betulin; lupeol; betulinic acid; 9,10-epoxy-18-hydroxyoctadecanoic acid; 9,10,18trihydroxyoctadecanoic acid; polyphenolic polymers and fatty acids from birch bark.Type: ApplicationFiled: August 23, 2001Publication date: April 18, 2002Applicant: Regents of the University of MinnesotaInventors: Pavel A. Krasutsky, Robert M. Carlson, Vitaliy V. Nesterenko, Igor M. Kolomitsyn, Chris F. Edwardson
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Publication number: 20020028960Abstract: The present invention provides a method for preparing betulin-3-acetate including alcoholyzing betulin 3,28-dibenzoate; a process for preparing betulin-3-acetate including: (1) acylating betulin to provide betulin 3,28-dibenzoate and (2) alcoholyzing betulin 3,28-dibenzoate to provide betulin-3-acetate; and a process for preparing betulinic acid including: (1) acylating betulin to provide betulin 3,28-dibenzoate; (2) alcoholyzing betulin 3,28-dibenzoate to provide betulin-3-acetate; (3) oxidizing betulin-3-acetate to provide betulinic aldehyde-3-acetate; (4) oxidizing betulinic aldehyde-3-acetate to provide betulinic acid-3-acetate; and (5) deprotecting betulinic acid-3-acetate to provide betulinic acid.Type: ApplicationFiled: June 29, 2001Publication date: March 7, 2002Applicant: Naturtek, LLC, Regents of the University of MinnesotaInventors: Pavel A. Krasutsky, Robert M. Carlson, Vitaliy V. Nesterenko
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Patent number: 6271405Abstract: The present invention provides a method for preparing betulin-3-acetate including alcoholyzing betulin 3,28-dibenzoate; a process for preparing betulin-3-acetate including: (1) acylating betulin to provide betulin 3,28-dibenzoate and (2) alcoholyzing betulin 3,28-dibenzoate to provide betulin-3-acetate; and a process for preparing betulinic acid including: (1) acylating betulin to provide betulin 3,28-dibenzoate; (2) alcoholyzing betulin 3,28-dibenzoate to provide betulin-3-acetate; (3) oxidizing betulin-3-acetate to provide betulinic aldehyde-3-acetate; (4) oxidizing betulinic aldehyde-3-acetate to provide betulinic acid-3-acetate; and (5) deprotecting betulinic acid-3 -acetate to provide betulinic acid.Type: GrantFiled: January 16, 2001Date of Patent: August 7, 2001Assignees: Regents of the University of Minnesota, Naturtek, LLCInventors: Pavel A. Krasutsky, Robert M. Carlson, Vitaliy V. Nesterenko
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Publication number: 20010007908Abstract: The present invention provides a method for preparing betulin-3-acetate including alcoholyzing betulin 3,28-dibenzoate; a process for preparing betulin-3-acetate including: (1) acylating betulin to provide betulin 3,28-dibenzoate and (2) alcoholyzing betulin 3,28-dibenzoate to provide betulin-3-acetate; and a process for preparing betulinic acid including: (1) acylating betulin to provide betulin 3,28-dibenzoate; (2) alcoholyzing betulin 3,28-dibenzoate to provide betulin-3-acetate; (3) oxidizing betulin-3-acetate to provide betulinic aldehyde-3-acetate; (4) oxidizing betulinic aldehyde-3-acetate to provide betulinic acid-3-acetate; and (5) deprotecting betulinic acid-3-acetate to provide betulinic acid.Type: ApplicationFiled: January 16, 2001Publication date: July 12, 2001Applicant: Regents of the University of Minnesota, Naturtek, LLCInventors: Pavel A. Krasutsky, Robert M. Carlson, Vitaliy V. Nesterenko
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Patent number: 6232481Abstract: The present invention provides a method for preparing betulin-3-acetate including alcoholyzing betulin 3,28-dibenzoate; a process for preparing betulin-3-acetate including: (1) acylating betulin to provide betulin 3,28-dibenzoate and (2) alcoholyzing betulin 3,28-dibenzoate to provide betulin-3-acetate; and a process for preparing betulinic acid including: (1) acylating betulin to provide betulin 3,28-dibenzoate; (2) alcoholyzing betulin 3,28-dibenzoate to provide betulin-3-acetate; (3) oxidizing betulin-3-acetate to provide betulinic aldehyde-3-acetate; (4) oxidizing betulinic aldehyde-3-acetate to provide betulinic acid-3-acetate; and (5) deprotecting betulinic acid-3-acetate to provide betulinic acid.Type: GrantFiled: January 11, 2000Date of Patent: May 15, 2001Assignees: Regents of the University of Minnesota, Naturtek, LLCInventors: Pavel A. Krasutsky, Robert M. Carlson, Vitaliy V. Nesterenko