Patents by Inventor Vito J. Mangiardi

Vito J. Mangiardi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Folate assay with ion exchange resin bound-free separation
    Patent number: 4135880
    Abstract: Improved competitive binding serum folate assay in which serum folate bound by folate-selective protein is separated from free serum folate by removal with an anion exchanger, preferably intermediate base anion exchange resin. Preferable are resins characterized by having an aliphatic lattice, particularly, a polyalkyleneamine lattice having tertiary and quaternary amine groups. The resin is advantageously added for the separation function in tablet form.
    Type: Grant
    Filed: August 19, 1977
    Date of Patent: January 23, 1979
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Vito J. Mangiardi, Henry J. Jeong, Nathan Lewin
  • Method for the analysis of thyroid hormones
    Patent number: 4086059
    Abstract: Method for competitive binding in diagnostic clinical testing for thyroid function in which blood serum is sufficiently acidified to inactivate binding of thyroid hormone to serum proteins. The serum test solution is then mixed directly with a buffered competitive binding protein solution without first separating inactivated endogenous serum proteins.
    Type: Grant
    Filed: May 16, 1975
    Date of Patent: April 25, 1978
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Howard Willner, Vito J. Mangiardi
  • Competitive binding thyroid assay with improved bound-free separation step
    Patent number: 4015939
    Abstract: Improved competitive binding thyroid hormone assay in which thyroid hormone bound by thyroid binding protein is separated from free thyroid hormone by removal with an intermediate base anion exchange resin. Typical are resins characterized by having an aliphatic lattice, particularly, a polyalkyleneamine lattice having tertiary and quaternary amine groups. The resin is advantageously added for the separation function in tablet form.
    Type: Grant
    Filed: May 12, 1976
    Date of Patent: April 5, 1977
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Nathan Lewin, Vito J. Mangiardi