Patents by Inventor Vittoria Villa

Vittoria Villa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 17-Substituted androsta-1,4-dien-3-one derivatives
    Patent number: 4873233
    Abstract: The invention relates to new 17-hydroxy androsta-1,4-diene-3-one derivatives of the following formula ##STR1## wherein each of R and R.sub.3, independently, is hydrogen or C.sub.1 -C.sub.6 alkyl;R.sub.1 is hydrogen, halogen or C.sub.1 -C.sub.6 alkyl;R.sub.2 is hydrogen or C.sub.1 -C.sub.6 alkyl;R.sub.4 is hydrogen or fluorine;R.sub.5 is (a) hydrogen or C.sub.1 -C.sub.6 alkyl; (b) phenyl unsubstituted or substituted by one or two substituents independently chosen from C.sub.1 -C.sub.6 alkyl, halogen and amino; (c) an acyl group; or (d) a hydroxy protecting group; and the pharmaceutically acceptable salts thereof,which are useful in therapy, in particular as anti-cancer agents.
    Type: Grant
    Filed: September 12, 1988
    Date of Patent: October 10, 1989
    Assignee: Farmitalia Carlo Erba S.p.a.
    Inventors: Vittoria Villa, Enrico di Salle, Paolo Lombardi
  • 6-Alkylidene 10 .beta.-alkynylestrene derivatives and pharmaceutical methods for their use
    Patent number: 4808578
    Abstract: The invention relates to 6-substituted 10.beta.-alkynylestrene derivatives wherein the 6 substituent is amino, azido, halogen or an alkylidene group and to corresponding 6,7-dihalo analogs.The invention provides also a process for the preparation of the above compounds and pharmaceutical compositions containing same.The compounds of the invention are useful aromatase inhibitors and can be used, e.g., in the treatment of hormone-dependent tumors and prostatic hyperplasia.
    Type: Grant
    Filed: December 15, 1986
    Date of Patent: February 28, 1989
    Assignee: Farmitalia Carlo Erba S. R. L.
    Inventors: Franco Faustini, Enrico di Salle, Vittoria Villa, Paolo Lombardi
  • Steroidic aromatase inhibitors
    Patent number: 4771043
    Abstract: The invention relates to 6-substituted androsta-1,4-diene-3,17-dione derivatives wherein the 6 substituent is an azido, amino or substituted amino group.The invention provides also a process for preparing the said compounds and pharmaceutical compositions containing same.The compounds of the invention are useful aromatase inhibitors and can be used, e.g., in the treatment of hormone-dependent tumors.
    Type: Grant
    Filed: July 21, 1986
    Date of Patent: September 13, 1988
    Assignee: Farmitalia Carlo Erba, S.p.A.
    Inventors: Franco Faustini, Roberto D'Alessio, Vittoria Villa, Enrico di Salle, Paolo Lombardi
  • 4-amino androstendione derivatives and process for their preparation
    Patent number: 4757061
    Abstract: The invention discloses 4-substituted androstendione derivatives of the following formula (I) ##STR1## wherein R is amino or substituted amino or azido,one of R.sub.1 and R.sub.2 is hydrogen and the other is hydrogen, alkyl, alkenyl or alkynyl, and(x) and (y) are each, independently, a single bond or a double bond.The compounds of formula (I) are useful aromatase inhibitors.
    Type: Grant
    Filed: February 10, 1986
    Date of Patent: July 12, 1988
    Assignee: Farmitalia Carlo Erba, S.p.A.
    Inventors: Franco Faustini, Roberto D'Alessio, Vittoria Villa, Enrico di Salle, Paolo Lombardi
  • Ester and amide derivatives of 13,14-didehydro prostaglandins
    Patent number: 4543353
    Abstract: Esters of 13,14-didehydro prostaglandins have been prepared.
    Type: Grant
    Filed: October 25, 1982
    Date of Patent: September 24, 1985
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Franco Faustini, Vittoria Villa, Carmelo Gandolfi, Enrico Di Salle