Abstract: Provided herein are compositions comprising CD4+ stem cell like memory T (TSCM) cells and their uses in the treatment of cancer, infection and autoimmune disorders.

Abstract: A method of producing a particle coating on one or more items is provided. The method comprises mixing supercritical carbon dioxide with a solution comprising dissolved material for forming particles. The method further comprises spraying the mixture into a precipitation chamber (316) to precipitate particles, wherein the chamber is at a pressure below a supercritical pressure of the supercritical fluid. The method also comprises capturing the precipitated particles on one or more items located within the chamber.

Abstract: Aspects of the disclosure generally relate to connecting panoramic images. One or more computing devices may load and display a first panoramic image captured at a first location and receive a selection of an area on the first panoramic image, the area corresponding to where a connection to other panoramic images may be made. The one or more computing devices may identify and display one or more nearby panoramic images which were captured near the first location and receive a selection of one of the one or more nearby panoramic images. The one or more computing devices may display the selected panoramic image and the first panoramic image and align the selected panoramic image with the first panoramic image such that the selected panoramic image is oriented in the same direction as the first panoramic image. The one or more computing devices may connect the selected panoramic image with the first panoramic image.

Abstract: Systems and methods for animating from audio in accordance with embodiments of the invention are illustrated. One embodiment includes a method for generating animation from audio. The method includes steps for receiving input audio data, generating an embedding for the input audio data, and generating several predictions for several tasks from the generated embedding. The several predictions includes at least one of blendshape weights, event detection, and/or voice activity detection. The method includes steps for generating a final prediction from the several predictions, where the final prediction includes a set of blendshape weights, and generating an output based on the generated final prediction.

Abstract: Implementations described herein relate to methods, systems, and computer-readable media to generate animations for a 3D avatar from input video captured at a client device. A camera may capture video of a face while a trained face detection model and a trained regression model output a set of FACS weights, head poses, and facial landmarks to be translated into the animations of the 3D avatar. Additionally, a higher level-of-detail may be intelligently selected based upon user preferences and/or computing conditions at the client device.

Abstract: Representative embodiments set forth herein disclose techniques for implementing improved links between paths of one or more file systems. According to some embodiments, techniques are disclosed for establishing a system volume and a data volume within a container. According to other embodiments, techniques are disclosed for establishing a link from a source path of a system volume within a container to a target path of a data volume within the container. According to yet other embodiments, techniques are disclosed for determining whether to allow a file system operation on a data volume of a container based on at least determining whether a target path is associated with a reference to a source path.

Abstract: The method, process and apparatus for very low temperature evaporation system novelty of the invention lies in the concept of method, process and apparatus for evaporation and concentration at very low temperature ranges from 5° C. to 80° C. to recover water vapour from liquids or solutions or industrial effluents or spentwash or industrial wastewater or juices or syrups or slurry or sludge or brine or sewer or wastewater or any other evaporative liquid materials in single or multiple effect heat exchanger arranged in horizontal or vertical manner with mechanical vapour compression system under vacuum. This very low temperature evaporation system operates at lowest temperature for maximum clean water recovery from liquids or solutions or industrial effluents or industrial wastewater. The apparatus for low temperature evaporation system eliminates or reduces the utilization of heat generation and rejection units along with other benefits like reduces water extraction from earth and energy losses.

Abstract: Disclosed is a system for documenting clinical trials, the system when operated identifies at least one publication related to a clinical trial entry to obtain documented clinical trial. The system comprises: an information repository comprising plurality of publications; a clinical trials registry database comprising a plurality of clinical trial entries; and a server arrangement. The server arrangement is configured to: obtain the plurality of publications; analyze the plurality of publications, using a filtering module, to determine a filtered set of publications; obtain the plurality of clinical trial entries; analyze a context of each of the publications in the filtered set and each of the plurality of clinical trial entries using a mapping module to identify a relationship of each of the publication with at least one of the plurality of clinical trial entries; and associate the plurality of clinical trial entries with publications related thereto to obtain documented clinical trials.

Abstract: Aspects of the disclosure generally relate to connecting panoramic images. One or more computing devices may load and display a first panoramic image captured at a first location and receive a selection of an area on the first panoramic image, the area corresponding to where a connection to other panoramic images may be made. The one or more computing devices may identify and display one or more nearby panoramic images which were captured near the first location and receive a selection of one of the one or more nearby panoramic images. The one or more computing devices may display the selected panoramic image and the first panoramic image and align the selected panoramic image with the first panoramic image such that the selected panoramic image is oriented in the same direction as the first panoramic image. The one or more computing devices may connect the selected panoramic image with the first panoramic image.

Abstract: Methods for inducing CD8+ T cells to express a CD62LhiCD44lo naïve-like phenotype are provided. One embodiment provides a pharmaceutical composition containing CD8+ T cells induced to express a CD62LhiCD44lo naïve-like phenotype and optionally an excipient. The CD8+ T cells can be induced by contacting them with an effective amount of a MEK1/2 inhibitor. An exemplary MEK1/2 inhibitor is Selumetinib. The induced CD8+ cells can be used to treat cancer, reduce tumor burden, or treat infections in a subject in need thereof.

Abstract: A handheld user device includes a monocular camera to capture a feed of images of a local scene and a processor to select, from the feed, a keyframe and perform, for a first image from the feed, stereo matching using the first image, the keyframe, and a relative pose based on a pose associated with the first image and a pose associated with the keyframe to generate a sparse disparity map representing disparities between the first image and the keyframe. The processor further is to determine a dense depth map from the disparity map using a bilateral solver algorithm, and process a viewfinder image generated from a second image of the feed with occlusion rendering based on the depth map to incorporate one or more virtual objects into the viewfinder image to generate an AR viewfinder image. Further, the processor is to provide the AR viewfinder image for display.

Abstract: Aspects of the disclosure generally relate to connecting panoramic images. One or more computing devices may load and display a first panoramic image captured at a first location and receive a selection of an area on the first panoramic image, the area corresponding to where a connection to other panoramic images may be made. The one or more computing devices may identify and display one or more nearby panoramic images which were captured near the first location and receive a selection of one of the one or more nearby panoramic images. The one or more computing devices may display the selected panoramic image and the first panoramic image and align the selected panoramic image with the first panoramic image such that the selected panoramic image is oriented in the same direction as the first panoramic image. The one or more computing devices may connect the selected panoramic image with the first panoramic image.

Abstract: Disclosed is system comprising data processing arrangement including processors configured to receive sentences from unlabeled training data set; tokenize, using tokenizer module, sentences to obtain tokens; generate character level features for character of tokens of sentences; generate token level feature for each token of the sentences, wherein token level feature of token in sentence is identified using token coordinates of token and token coordinates of tokens neighboring token in sentence; train artificial neural network adapted to identify entities in sentences to determine first trend set, wherein training is based on received sentences, character level features for each character of tokens of sentences and token level feature for tokens of sentences; train the artificial neural network on set of labelled data to determine second trend set; identify, using identifier module, entity in text content, wherein identifier module uses first trend set and second trend set determined by artificial neural netw

Abstract: Systems and methods for animating from audio in accordance with embodiments of the invention are illustrated. One embodiment includes a method for generating animation from audio. The method includes steps for receiving input audio data, generating an embedding for the input audio data, and generating several predictions for several tasks from the generated embedding. The several predictions includes at least one of blendshape weights, event detection, and/or voice activity detection. The method includes steps for generating a final prediction from the several predictions, where the final prediction includes a set of blendshape weights, and generating an output based on the generated final prediction.

Abstract: A handheld user device includes a monocular camera to capture a feed of images of a local scene and a processor to select, from the feed, a keyframe and perform, for a first image from the feed, stereo matching using the first image, the keyframe, and a relative pose based on a pose associated with the first image and a pose associated with the keyframe to generate a sparse disparity map representing disparities between the first image and the keyframe. The processor further is to determine a dense depth map from the disparity map using a bilateral solver algorithm, and process a viewfinder image generated from a second image of the feed with occlusion rendering based on the depth map to incorporate one or more virtual objects into the viewfinder image to generate an AR viewfinder image. Further, the processor is to provide the AR viewfinder image for display.

Abstract: Representative embodiments set forth herein disclose techniques for implementing improved links between paths of one or more file systems. According to some embodiments, techniques are disclosed for establishing a system volume and a data volume within a container. According to other embodiments, techniques are disclosed for establishing a link from a source path of a system volume within a container to a target path of a data volume within the container. According to yet other embodiments, techniques are disclosed for determining whether to allow a file system operation on a data volume of a container based on at least determining whether a target path is associated with a reference to a source path.

Abstract: Disclosed is system comprising data processing arrangement including processors configured to receive sentences from unlabeled training data set; tokenize, using tokenizer module, sentences to obtain tokens; generate character level features for character of tokens of sentences; generate token level feature for each token of the sentences, wherein token level feature of token in sentence is identified using token coordinates of token and token coordinates of tokens neighboring token in sentence; train artificial neural network adapted to identify entities in sentences to determine first trend set, wherein training is based on received sentences, character level features for each character of tokens of sentences and token level feature for tokens of sentences; train the artificial neural network on set of labelled data to determine second trend set; identify, using identifier module, entity in text content, wherein identifier module uses first trend set and second trend set determined by artificial neural netw

Abstract: Disclosed is a system for documenting clinical trials, the system when operated identifies at least one publication related to a clinical trial entry to obtain documented clinical trial. The system comprises: an information repository comprising plurality of publications; a clinical trials registry database comprising a plurality of clinical trial entries; and a server arrangement. The server arrangement is configured to: obtain the plurality of publications; analyze the plurality of publications, using a filtering module, to determine a filtered set of publications; obtain the plurality of clinical trial entries; analyze a context of each of the publications in the filtered set and each of the plurality of clinical trial entries using a mapping module to identify a relationship of each of the publication with at least one of the plurality of clinical trial entries; and associate the plurality of clinical trial entries with publications related thereto to obtain documented clinical trials.

Abstract: Compositions and methods of their use to detect and treat anti-PD1 therapy resistance are provided herein. Compositions that immunospecifically bind and deplete dysfunctional T cells are provided. The dysfunctional T cells that are depleted include CD38+PD-1+ T cells, CD38+CD8+ T-cells, or both. The dysfunctional T cells can be depleted, for example, by administering an antibody or fusion protein that specifically binds to dysfunctional T cells and promotes their depletion. In one embodiment the antibody is a bispecific antibody that can be specific for CD38 and CD8, or it can be specific for CD38 and PD-1. Also disclosed is a method of detecting and treating anti-PD1 therapy resistance by measuring the amount of CD38+PD1+CD8 T cells in blood or tissue samples obtained from a subject prior to anti-PD1 therapy and administering an anti-CD38/CD8 or anti-CD38/PD-1 depleting/blocking antibody to the subject prior to anti-PD1 therapy.

Abstract: Methods and compositions for inducing CD8+ T cells to express a CD62LhiCD44lo naïve-like phenotype are provided. One embodiment provides a pharmaceutical composition containing CD8+ T cells induced to express a CD62LhiCD44lo naïve-like phenotype and optionally an excipient. The CD8+ T cells can be induced by contacting them with an effective amount of a MEK1/2 inhibitor. An exemplary MEK1/2 inhibitor is Selumetinib. The induced CD8+ cells can be used to treat cancer, reduce tumor burden, or treat infections in a subject in need thereof.