Patents by Inventor Vladimir Saudek

Vladimir Saudek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5475308
    Abstract: Process for the excitation and acquisition of NMR signals, particularly for the analysis of molecules dispersed in a solvent, such as for example water. A specimen to be analyzed is first subjected to a series of impulses (1) corresponding to a high resolution NMR test to be carried out. Then there is applied to the specimen a first pulsed field gradient (2) in a given direction, and then the specimen is subjected to a 180.degree. selective pulsed radiofrequency field (3) affecting all the spectrum except the resonance frequency of the water or corresponding solvent. Then a second pulsed field gradient (4) identical to the first is applied to the specimen. Then the acquisition and processing of the resulting NMR signals are effected.
    Type: Grant
    Filed: November 15, 1993
    Date of Patent: December 12, 1995
    Assignee: Sadis Bruker Spectrospin Societe Anonyme De Diffusion De L'Instrumentation Scientifique Bruker Spectrospin
    Inventors: Martial Piotto, Vladimir Sklenar, Vladimir Saudek
  • Patent number: 4745161
    Abstract: The invention pertains to copolymers activated for bonding of biologically active compounds and to a method for preparation thereof.Soluble and biodegradable copolymers activated for bonding of biologically active compounds which have their main chain formed from units of aspartic acid or glutamic acid, or both, or also from units of other amino acids, according to the general formula I ##STR1## where n is 1 or 2, m is 1 or 2, a+b+c is 100, a is 0.5 to 100, b is 0 to 99.5, c is 0 to 80; the substituent R.sup.1 is --NH--NH.sub.2, --N.tbd.N or ##STR2## where x is 2 to 6, R.sup.2 is --NH(CH.sub.2).sub.x OH where x=2 to 6; and R.sup.3 is methyl, 2-propyl, 2-methylpropyl, butyl, 2-butyl, benzyl or 4-hydroxybenzyl, and the molecular weight is 5,000 to 1,000,000.
    Type: Grant
    Filed: April 1, 1986
    Date of Patent: May 17, 1988
    Assignee: Ceskoslovenska akademie ved
    Inventors: Vladimir Saudek, Frantisek Rypacek, Jaroslav Drobnik
  • Patent number: 4659849
    Abstract: A macromolecular compound with antitumor activity in which hydroxy groups in side chains of a polymer have the character of primary, secondary or tertiary alcohols and are completely or in part esterified with carboxyl in the position C4 of 1,2,4-tricarboxybenzene, whereas the carboxyls in positions C1 and C2 bind an atom of platinum with coordination bonded amino ligands.A method for producing the macromolecular compound consists in acylation of the polymer carrying alcohol groups with chloride anhydride of trimellitic acid of the formula II, ##STR1## hydrolyzing the anhydride in the subsequent step, and bonding an atom of bivalent platinum carrying an amino ligand to the formed vicinal carboxylic groups.
    Type: Grant
    Filed: November 8, 1985
    Date of Patent: April 21, 1987
    Assignee: Ceskoslovenska akademie ved
    Inventors: Jaroslav Drobnik, Dagmar Noskova, Frantisek Rypacek, Marie Metalova, Vladimir Saudek
  • Patent number: 4245064
    Abstract: The invention relates to a solid insoluble carrier which is activated for bonding of nucleophilic groups and to a method of its preparation. The carrier contains active groups --O.CO.O.R, where R is the residue selected from the group comprising nitrophenyl, dinitrophenyl, trichlorophenyl, pentachlorophenyl, N-succinimidyl, N-phthalimidyl, and 8-quinolinyl. Active groups are bonded to polysaccharides, phenol-formaldehyde resins, polyacrylates, or polyacrylamides. The invention further relates to a method for preparation of the polymeric carrier, which consists in treatment of polymers carrying hydroxyl functions and selected from the group comprising polysaccharides, phenol-formaldehyde resins, polyacrylates, and polyacrylamides, with esters of chloroformic acid which contain the above mentioned active groups.
    Type: Grant
    Filed: February 12, 1979
    Date of Patent: January 13, 1981
    Assignee: Ceskoslovenska akademie ved
    Inventors: Jaroslav Drobnik, Jaroslav Kalal, Jiri Labsky, Vladimir Saudek, Frantisek Svec