Patents by Inventor Volker Gerstner
Volker Gerstner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7933083Abstract: A diaphragm device with which individual wavelengths or ranges of wavelengths in the path of a beam of spectrally dispersed light can be suppressed. Such a diaphragm device comprises at least one array of diaphragms, wherein the individual diaphragms of the array are arranged in a definite relation to each other and may be coupled in the path of the beam and each diaphragm of the array in the coupled state is arranged in a given relation to an individual wavelength or a range of wavelengths.Type: GrantFiled: April 27, 2010Date of Patent: April 26, 2011Assignee: Carl Zeiss MicroImaging GmbHInventors: Jörg Steinert, Thomas Mehner, Volker Gerstner
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Publication number: 20100259844Abstract: A diaphragm device with which individual wavelengths or ranges of wavelengths in the path of a beam of spectrally dispersed light can be suppressed. Such a diaphragm device comprises at least one array of diaphragms, wherein the individual diaphragms of the array are arranged in a definite relation to each other and may be coupled in the path of the beam and each diaphragm of the array in the coupled state is arranged in a given relation to an individual wavelength or a range of wavelengths.Type: ApplicationFiled: April 27, 2010Publication date: October 14, 2010Inventors: Jörg Steinert, Thomas MEHNER, Volker GERSTNER
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Patent number: 7706090Abstract: A diaphragm device with which individual wavelengths or ranges of wavelengths in the path of a beam of spectrally dispersed light can be suppressed. Such a diaphragm device comprises at least one array of diaphragms, wherein the individual diaphragms of the array are arranged in a definite relation to each other and may be coupled in the path of the beam and each diaphragm of the array in the coupled state is arranged in a given relation to an individual wavelength or a range of wavelengths.Type: GrantFiled: January 12, 2006Date of Patent: April 27, 2010Assignee: Carl Zeiss Microimaging GmbHInventors: Jörg Steinert, Thomas Mehner, Volker Gerstner
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Patent number: 7420674Abstract: A method and/or arrangement for the analysis of fluorescing samples in an image-generating microscope system, preferably a laser scanning microscope, wherein the sample is scanned point-by-point or line-by-line in at least one surface section and a dispersive splitting of the radiation coming from the sample is carried out during the scanning, wherein the split radiation is detected by at least one line of detector elements in a wavelength-dependent manner, a selection of two-dimensional or three-dimensional sample parts which correspond to pre-stored two-dimensional or three-dimensional geometric objects or the like is carried out based on the recorded and stored intensity distribution of at least one of these detection elements and/or at least one other detection element for the radiation reflected from the sample by image processing, and an analysis of the spectral signature and/or spatial spectral sequence is carried out for at least a portion of these sample regions with respect to the fluorescence markeType: GrantFiled: May 14, 2003Date of Patent: September 2, 2008Assignee: Carl Zeiss MicroImaging GmbHInventors: Volker Gerstner, Joerg Lindenau
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Publication number: 20080043786Abstract: A tunable lighting source, especially for a microscope, which contains a laser, in which the lighting source delivers spectrally variable and spatially coherent radiation. The tunable lighting source is based on a structured substrate coated with a laser medium, the structured substrate provided with the laser medium having a geometrically variable structure and delivering spatially coherent radiation by energy excitation.Type: ApplicationFiled: August 17, 2007Publication date: February 21, 2008Inventors: Stefan Wilhelm, Volker Gerstner, Peter Westphal, Dieter Huhse
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Patent number: 7271897Abstract: A method of optical detection of characteristic quantities of an illuminated specimen comprising detecting a signal that is backscattered, reflected and/or fluoresced and/or transmitted from the specimen by a spatially resolving detector wherein radiation coming from the specimen is imaged on the detector, shifting the position of the radiation which is measured in a spatially resolved manner relative to the detector and determining intermediate values by an algorithm from the signals measured in different shifts for purposes of increasing the spatial resolution of the detector. An arrangement for performing the method is also disclosed.Type: GrantFiled: July 15, 2005Date of Patent: September 18, 2007Assignee: Carl Zeiss Jena GmbHInventors: Ralf Wolleschensky, Gunter Moehler, Volker Gerstner
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Publication number: 20070146900Abstract: A diaphragm device with which individual wavelengths or ranges of wavelengths in the path of a beam of spectrally dispersed light can be suppressed. Such a diaphragm device comprises at least one array of diaphragms, wherein the individual diaphragms of the array are arranged in a definite relation to each other and may be coupled in the path of the beam and each diaphragm of the array in the coupled state is arranged in a given relation to an individual wavelength or a range of wavelengths.Type: ApplicationFiled: January 12, 2006Publication date: June 28, 2007Inventors: Jorg Steinert, Thomas Mehner, Volker Gerstner
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Publication number: 20060000984Abstract: A method of optical detection of characteristic quantities of an illuminated specimen comprising detecting a signal that is backscattered, reflected and/or fluoresced and/or transmitted from the specimen by a spatially resolving detector wherein radiation coming from the specimen is imaged on the detector, shifting the position of the radiation which is measured in a spatially resolved manner relative to the detector and determining intermediate values by an algorithm from the signals measured in different shifts for purposes of increasing the spatial resolution of the detector. An arrangement for performing the method is also disclosed.Type: ApplicationFiled: July 15, 2005Publication date: January 5, 2006Inventors: Ralf Wolleschensky, Gunter Moehler, Volker Gerstner
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Patent number: 6947133Abstract: A method of optical detection of characteristic quantities of an illuminated specimen comprising detecting a signal that is backscattered, reflected and/or fluoresced and/or transmitted from the specimen by a spatially resolving detector wherein radiation coming from the specimen is imaged on the detector, shifting the position of the radiation which is measured in a spatially resolved manner relative to the detector and determining intermediate values by an algorithm from the signals measured in different shifts for purposes of increasing the spatial resolution of the detector. An arrangement for performing the method is also disclosed.Type: GrantFiled: August 7, 2001Date of Patent: September 20, 2005Assignee: Carl Zeiss Jena GmbHInventors: Ralf Wolleschensky, Gunter Moehler, Volker Gerstner
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Publication number: 20050179892Abstract: A method and/or arrangement for the analysis of fluorescing samples in an image-generating microscope system, preferably a laser scanning microscope, wherein the sample is scanned point-by-point or line-by-line in at least one surface section and a dispersive splitting of the radiation coming from the sample is carried out during the scanning, wherein the split radiation is detected by at least one line of detector elements in a wavelength-dependent manner, a selection of two-dimensional or three-dimensional sample parts which correspond to pre-stored two-dimensional or three-dimensional geometric objects or the like is carried out based on the recorded and stored intensity distribution of at least one of these detection elements and/or at least one other detection element for the radiation reflected from the sample by image processing, and an analysis of the spectral signature and/or spatial spectral sequence is carried out for at least a portion of these sample regions with respect to the fluorescence markeType: ApplicationFiled: May 14, 2003Publication date: August 18, 2005Inventors: Volker Gerstner, Joerg Lindenau
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Publication number: 20050063051Abstract: An arrangement for direct input coupling of a laser, preferably of a short-pulse laser, for nonlinear sample excitation which is located outside of the microscope housing, into the beam path of a laser scanning microscope (LSM), comprising a housing in which is integrated an adjusting laser that can be coupled into the microscope beam path by beam splitters, wherein the housing is advantageously integrated so as to be insertable in the scan module of the LSMA, and a beam splitter for the direct coupling laser has high transmission in the direction of the objective and, further, partial transmission for back-reflections of the adjusting laser coming from the specimen for adjusting the overlapping of the adjusting laser and direct coupling laser.Type: ApplicationFiled: July 9, 2004Publication date: March 24, 2005Inventors: Ralph Lange, Stefan Wilhelm, Volker Gerstner, Roland Scheler, Michael Goelles, Joerg-Michael Funk
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Patent number: 6819415Abstract: A method and arrangement are disclosed for increasing the depth contrast in microscope imaging. The method and implementation described can be designated as structured illumination for generating quasi-confocal optical sections. In implementing the method, a grating structure located in the field diaphragm plane of a microscope, the object plane and the TV intermediate image plane of a microscope are arranged confocally. The term “confocally” refers to the fact that the grating, object and the intermediate image plane are positioned on optically conjugate planes. By this arrangement, the grating structure is projected in the object plane of the microscope and the object which is structured in this way is imaged in the TV intermediate image plane of the microscope by the optical system following it. Optical sections are generated by calculating the modulation depth of the structured object.Type: GrantFiled: August 12, 2002Date of Patent: November 16, 2004Assignee: Carl Zeiss Jena GmbHInventors: Volker Gerstner, Frank Hecht, Ralph Lange, Helmut Bloos
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Patent number: 6741346Abstract: Process for detecting the phenomenon of fluorescence in a microscope, wherein the sample is irradiated by a modulated and/or pulsed laser light source, and the fluorescence is detected at least in two different phase positions of the detector.Type: GrantFiled: December 21, 2001Date of Patent: May 25, 2004Assignee: Carl Zeiss Jena GmbHInventors: Volker Gerstner, Ralf Wolleschensky
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Publication number: 20030086067Abstract: The invention relates to a method for increasing the depth of contrast during microscopic imaging. The method and implementation described can be designated as structured illumination, which creates quasi-confocal optical sections. During the implementation of the method, a grid structure, located in the illumination field stop plane of a microscope, the object plane and the TV intermediate-image plane of a microscope are arranged “confocally”. This assembly enables the grid structure to be projected into the object plane of the microscope and the object, thus structured, to be reproduced on the TV intermediate-image plane using the following optical system. Optical sections are created by the calculation of the modulation depth of the structured object. The object is reproduced perpendicular to the direction of observation on several focus planes, to achieve a 3-dimensional registration of said object and is detected using an array-detector (e.g. CCD camera).Type: ApplicationFiled: August 12, 2002Publication date: May 8, 2003Inventors: Volker Gerstner, Frank Hecht, Ralph Lange, Helmut Bloos
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Publication number: 20020036775Abstract: A method of optical detection of characteristic quantities of an illuminated specimen comprising detecting a signal that is backscattered, reflected and/or fluoresced and/or transmitted from the specimen by a spatially resolving detector wherein radiation coming from the specimen is imaged on the detector, shifting the position of the radiation which is measured in a spatially resolved manner relative to the detector and determining intermediate values by an algorithm from the signals measured in different shifts for purposes of increasing the spatial resolution of the detector. An arrangement for performing the method is also disclosed.Type: ApplicationFiled: August 7, 2001Publication date: March 28, 2002Applicant: Carl Zeiss Jena GmbHInventors: Ralf Wolleschensky, Gunter Moehler, Volker Gerstner