Patents by Inventor Volker Schellenberger

Volker Schellenberger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Growth hormone polypeptides fused to extended recombinant polypeptides and methods of making and using same
    Patent number: 8680050
    Abstract: The present invention relates to compositions comprising growth hormone linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in administration to animals.
    Type: Grant
    Filed: August 2, 2010
    Date of Patent: March 25, 2014
    Assignee: Amunix Operating Inc.
    Inventors: Volker Schellenberger, Joshua Silverman, Willem P. Stemmer, Chia-Wei Wang, Nathan Geething, Jeffrey L. Cleland
  • Extended recombinant polypeptides and compositions comprising same
    Patent number: 8673860
    Abstract: The present invention relates to compositions comprising biologically active proteins linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of glucose-related diseases, metabolic diseases, coagulation disorders, and growth hormone-related disorders and conditions.
    Type: Grant
    Filed: February 3, 2010
    Date of Patent: March 18, 2014
    Assignee: Amunix Operating Inc.
    Inventors: Volker Schellenberger, Joshua Silverman, Chia-wel Wang, Benjamin Spink, Willem P. Stemmer, Nathan C. Geething, Wayne To, Jeffrey L. Cleland
  • Alpha 1-antitrypsin compositions and methods of making and using same
    Patent number: 8557961
    Abstract: The present invention relates to compositions comprising alpha 1-antitrypsin linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in the treatment of alpha 1-antitrypsin-related diseases, disorders, and conditions.
    Type: Grant
    Filed: April 1, 2011
    Date of Patent: October 15, 2013
    Assignee: Amunix Operating Inc.
    Inventors: Joshua Silverman, Volker Schellenberger, Willem P. Stemmer, Chia-Wei Wang, Ian M. Brennan
  • Unstructured recombinant polymers and compositions comprising same
    Patent number: 8492530
    Abstract: The present invention provides unstructured recombinant polymers (URPs) and proteins containing one or more of the URPs. The present invention also provides microproteins, toxins and other related proteinaceous entities, as well as genetic packages displaying these entities. The present invention also provides recombinant polypeptides including vectors encoding the subject proteinaceous entities, as well as host cells comprising the vectors. The subject compositions have a variety of utilities including a range of pharmaceutical applications.
    Type: Grant
    Filed: November 3, 2010
    Date of Patent: July 23, 2013
    Assignee: Amunix Operating Inc.
    Inventors: Volker Schellenberger, Willem P. Stemmer, Chia-Wei Wang, Michael D. Scholle, Mikhail Popkov, Nathaniel C. Gordon, Andreas Crameri
  • BINDING FUSION PROTEINS, BINDING FUSION PROTEIN-DRUG CONJUGATES, XTEN-DRUG CONJUGATES AND METHODS OF MAKING AND USING SAME
    Publication number: 20130165389
    Abstract: The present invention relates to binding fusion protein compositions comprising targeting moieties linked to extended recombinant polypeptide (XTEN), binding fusion protein-drug conjugate compositions, and XTEN-drug conjugate compositions, isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of diseases, disorders, and conditions.
    Type: Application
    Filed: September 28, 2012
    Publication date: June 27, 2013
    Applicant: Amunix Operating Inc.
    Inventors: Volker Schellenberger, Joshua Silverman, Chia-wei Wang, Benjamin Spink, Willem P. Stemmer, Susan E. Alters, Nathan Geething
  • Phosphate limited inducible promoter and a expression system
    Patent number: 8415120
    Abstract: An evolvable production strain of B. subtilis exhibiting continuous or high level expression during protein evolution is described. An evolved Bacillus subtilis pstS promoter facilitates screening and production of secreted proteins.
    Type: Grant
    Filed: November 19, 2010
    Date of Patent: April 9, 2013
    Assignee: Danisco US Inc.
    Inventors: Katherine D. Collier, Edwin Lee, Nicholas Leiva, Thomas B. Morrison, Volker Schellenberger, Olga V. Selifonova, Adam C. Kean
  • COMPOSITIONS AND METHODS FOR IMPROVING PRODUCTION OF RECOMBINANT POLYPEPTIDES
    Publication number: 20130039884
    Abstract: The present invention relates to biologically active polypeptides linked to one or more accessory polypeptides. The present invention also provides recombinant polypeptides including vectors encoding the subject proteinaceous entities, as well as host cells comprising the vectors. The subject compositions have a variety of utilities including a range of pharmaceutical applications.
    Type: Application
    Filed: May 11, 2012
    Publication date: February 14, 2013
    Applicant: Amunix Operationg Inc.
    Inventors: Oren Bogin, Willem P. Stemmer, Volker Schellenberger, Yong Yin, Chia-wei Wang, Nathan C. Geething
  • Factor VIII Compositions and Methods of Making and Using Same
    Publication number: 20130017997
    Abstract: The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor VIII-related diseases, disorders, and conditions.
    Type: Application
    Filed: February 2, 2012
    Publication date: January 17, 2013
    Applicant: Amunix Operating Inc.
    Inventors: Volker Schellenberger, Pei-Yun Chang, Fatbardha Varfaj, John Kulman, Tongyao Liu, Garabet G. Toby, Haiyan Jiang, Robert Peters, Deping Wang, Baisong Mei, Joshua Silverman, Chia-Wei Wang, Benjamin Spink, Nathan Geething
  • COAGULATION FACTOR VII COMPOSITIONS AND METHODS OF MAKING AND USING SAME
    Publication number: 20120263701
    Abstract: The present invention relates to compositions comprising factor VII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of coagulation factor-related diseases, disorders, and conditions.
    Type: Application
    Filed: August 2, 2010
    Publication date: October 18, 2012
    Inventors: Volker Schellenberger, Willem P. Stemmer, Nathan C. Geething, Wayne To, Joshua Silverman, Chia-wei Wang, Benjamin Spink
  • COAGULATION FACTOR IX COMPOSITIONS AND METHODS OF MAKING AND USING SAME
    Publication number: 20120263703
    Abstract: The present invention relates to compositions comprising factor DC coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of coagulation factor-related diseases, disorders, and conditions.
    Type: Application
    Filed: August 2, 2010
    Publication date: October 18, 2012
    Applicant: AMUNIX OPERATING INC
    Inventors: Volker Schellenberger, Willem P. Stemmer, Nathan C. Geething, Wayne To, Joshua Silverman, Chia-wei Wang, Benjamin Spink
  • BIOLOGICALLY ACTIVE PROTEINS HAVING INCREASED IN VIVO AND/OR IN VITRO STABILITY
    Publication number: 20120230947
    Abstract: The present invention provides unstructured recombinant polymers (URPs) and proteins containing one or more of the URPs. The present invention also provides microproteins, toxins and other related proteinaceous entities, as well as genetic packages displaying these entities. The present invention also provides recombinant polypeptides including vectors encoding the subject proteinaceous entities, as well as host cells comprising the vectors. The subject compositions have a variety of utilities including a range of pharmaceutical applications.
    Type: Application
    Filed: April 4, 2012
    Publication date: September 13, 2012
    Applicant: AMUNIX OPERATING INC.
    Inventors: VOLKER SCHELLENBERGER, WILLEM P. STEMMER, CHIA-WEI WANG, MICHAEL D. SCHOLLE, MIKHAIL POPKOV, NATHANIEL C. GORDON, ANDREAS CRAMERI
  • UNSTRUCTURED RECOMBINANT POLYMERS AND USES THEREOF
    Publication number: 20120220011
    Abstract: The present invention provides unstructured recombinant polymers (URPs) and proteins containing one or more of the URPs. The present invention also provides microproteins, toxins and other related proteinaceous entities, as well as genetic packages displaying these entities. The present invention also provides recombinant polypeptides including vectors encoding the subject proteinaceous entities, as well as host cells comprising the vectors. The subject compositions have a variety of utilities including a range of pharmaceutical applications.
    Type: Application
    Filed: February 14, 2012
    Publication date: August 30, 2012
    Applicant: Amunix Operating Inc.
    Inventors: Volker Schellenberger, Willem P. Stemmer, Chia-wei Wang, Michael D. Scholle, Mikhail Popkov, Nathaniel C. Gordon, Andreas Crameri
  • FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME
    Publication number: 20120178691
    Abstract: The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor VIII-related diseases, disorders, and conditions.
    Type: Application
    Filed: March 16, 2012
    Publication date: July 12, 2012
    Applicant: Amunix Operating Inc.
    Inventors: Volker Schellenberger, Pei-Yun Chang, Fatbardha Varfaj, Joshua Silverman, Chia-Wei Wang, Benjamin Spink, Nathan Geething
  • Tab molecules
    Patent number: 8188240
    Abstract: The present invention relates to TAB molecules, ADEPT constructs directed against TAG-72, and their use in therapy.
    Type: Grant
    Filed: December 12, 2011
    Date of Patent: May 29, 2012
    Assignee: Danisco US Inc.
    Inventors: Judith A. Fox, M. Harunur Rashid, Martin Roberge, Volker Schellenberger
  • CAB MOLECULES
    Publication number: 20120107314
    Abstract: The present invention relates to CAB molecules, ADEPT constructs directed against CEA, and their use in therapy.
    Type: Application
    Filed: November 2, 2011
    Publication date: May 3, 2012
    Inventors: Judith A. Fox, Fiona A. Harding, Rashid M. Harunur, Volker Schellenberger
  • TAB MOLECULES
    Publication number: 20120094357
    Abstract: The present invention relates to TAB molecules, ADEPT constructs directed against TAG-72, and their use in therapy.
    Type: Application
    Filed: December 12, 2011
    Publication date: April 19, 2012
    Inventors: Judith A. Fox, M. Harunur Rashid, Martin Roberge, Volker Schellenberger
  • Multi-through Hole Testing Plate for High Throughput Screening
    Publication number: 20120094851
    Abstract: A method for holding samples for analysis and an apparatus thereof includes a testing plate with a pair of opposing surfaces and a plurality of holes. Each of the holes extends from one of the opposing surfaces to the other one of the opposing surfaces. The holes are arranged in groups, where each group has at least two rows and two columns of holes. The groups are arranged in sets, where each set has at least two rows and two columns of groups. To analyze samples, at least one of the opposing surfaces of the testing plate is immersed in a solution to be analyzed. A portion of the solution enters openings for each of the holes in the immersed opposing surface. Once the holes are filled with solution, the testing plate is removed and is held above a supporting surface. Surface tension holds the solution in each of the holes. The solution in one or more of the holes is then analyzed and the solution in one of these holes is identified for further study.
    Type: Application
    Filed: October 18, 2011
    Publication date: April 19, 2012
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Volker SCHELLENBERGER, Amy Deming Liu
  • TAB molecules
    Patent number: 8101728
    Abstract: The present invention relates to TAB molecules, ADEPT constructs directed against TAG-72, and their use in therapy.
    Type: Grant
    Filed: April 21, 2006
    Date of Patent: January 24, 2012
    Assignee: Danisco US Inc.
    Inventors: Judith A. Fox, M. Harunur Rashid, Martin Roberge, Volker Schellenberger
  • CAB molecules
    Patent number: 8088609
    Abstract: The present invention relates to CAB molecules, ADEPT constructs directed against CEA, and their use in therapy.
    Type: Grant
    Filed: April 12, 2005
    Date of Patent: January 3, 2012
    Assignee: Danisco US Inc.
    Inventors: Judith A. Fox, Fiona A. Harding, Rashid M. Harunur, Volker Schellenberger
  • BIFUNCTIONAL POLYPEPTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF METABOLIC AND CARDIOVASCULAR DISEASES
    Publication number: 20110312881
    Abstract: The present invention relates to compositions comprising combinations of biologically active proteins linked to extended recombinant polymer, methods of production of the compositions and their use in treatment of metabolic and cardiovascular diseases, disorders and conditions.
    Type: Application
    Filed: December 21, 2010
    Publication date: December 22, 2011
    Applicant: AMUNIX, Inc.
    Inventors: Joshua Silverman, Volker Schellenberger, Willem P. Stemmer, Jeffrey L. Cleland