Patents by Inventor Voon Loong Chan

Voon Loong Chan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7192725
    Abstract: Purified and isolated nucleic acid molecules are provided which encode a FlaC flagellin protein of a strain of Campylobacter, particularly C. jejuni, or a fragment or an analog of the FlaC flagellin protein. The nucleic acid molecules may be used to produce proteins free of contaminants derived from bacteria normally containing the FlaA or FlaB proteins for purposes of diagnostics and medical treatment. Furthermore, the nucleic acid molecules, proteins encoded thereby and antibodies raised against the proteins, may be used in the diagnosis of infection.
    Type: Grant
    Filed: April 29, 2003
    Date of Patent: March 20, 2007
    Assignee: University of Toronto
    Inventors: Voon Loong Chan, Helena Louie
  • Publication number: 20040006037
    Abstract: Purified and isolated nucleic acid molecules are provided which encode a FlaC flagellin protein of a strain of Campylobacter, particularly C. jejuni, or a fragment or an analog of the FlaC flagellin protein. The nucleic acid molecules may be used to produce proteins free of contaminants derived from bacteria normally containing the FlaA or FlaB proteins for purposes of diagnostics and medical treatment. Furthermore, the nucleic acid molecules, proteins encoded thereby and antibodies raised against the proteins, may be used in the diagnosis of infection.
    Type: Application
    Filed: April 29, 2003
    Publication date: January 8, 2004
    Inventors: Voon Loong Chan, Helena Louie
  • Patent number: 6585980
    Abstract: Purified and isolated nucleic acid molecules are provided which encode a FlaC flagellin protein of a strain of Campylobacter, particularly C. jejuni, or a fragment or an analog of the FlaC flagellin protein. The nucleic acid molecules may be used to produce proteins free of contaminants derived from bacteria normally containing the FlaA or FlaB proteins for purposes of diagnostics and medical treatment. Furthermore, the nucleic acid molecules, proteins encoded thereby and antibodies raised against the proteins, may be used in the diagnosis of infection.
    Type: Grant
    Filed: May 19, 2000
    Date of Patent: July 1, 2003
    Assignee: The University of Toronto
    Inventors: Voon Loong Chan, Helena Louie
  • Patent number: 6245516
    Abstract: Nucleic acid probes and a method for their use in detecting and identifying Campylobacter, Helicobacter, and Arcobacter spp. bacterial pathogens are described. A method for prepg. specific nucleic acid probes for the detection of identification of any other bacterial pathogens is also provided.
    Type: Grant
    Filed: December 7, 1999
    Date of Patent: June 12, 2001
    Inventors: Shahnaz Tahihra Al Rashid, Voon Loong Chan
  • Patent number: 6211159
    Abstract: Purified and isolated nucleic acid molecules are provided which encode a FlaC flagellin protein of a strain of Campylobacter, particularly C. jejuni, or a fragment or an analog of the FlaC flagellin protein. The nucleic acid molecules may be used to produce proteins free of contaminants derived from bacteria normally containing the FlaA or FlaB proteins for purposes of diagnostics and medical treatment. Furthermore, the nucleic acid molecules, proteins encoded thereby and antibodies raised against the proteins, may be used in the diagnosis of infection.
    Type: Grant
    Filed: April 11, 1997
    Date of Patent: April 3, 2001
    Assignee: University of Toronto
    Inventors: Voon Loong Chan, Helena Louie
  • Patent number: 6087105
    Abstract: A protein associated with adherence and invasion of Campylobacter spp. including C. jejuni and C. coli is provided. Methods are disclosed for detecting Campylobacter spp. including C. jejuni and C. coli in a biological sample by determining the presence of the protein or a nucleic acid molecule encoding the protein in the sample. Compositions for treatment of infections diseases and vaccines are also described.
    Type: Grant
    Filed: April 8, 1998
    Date of Patent: July 11, 2000
    Inventors: Voon Loong Chan, Angela Joe, Yuwen Hong
  • Patent number: 6020125
    Abstract: Purified and isolated nucleic acid molecules are provided which encode a basal body rod protein of a strain of Campylobacter, particularly C. jejuni, or a fragment or an analog of the basal body rod protein. The nucleic acid molecules may be used to produce proteins free of contaminants derived from bacteria normally containing the FlgF or FlgG proteins for purposes of diagnostics and medical treatment. Furthermore, the nucleic acid molecules, proteins encoded thereby and antibodies raised against the proteins, may be used in the diagnosis of infection.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: February 1, 2000
    Assignee: Connaught Laboratories Limited
    Inventors: Voon Loong Chan, Helena Louie
  • Patent number: 6013501
    Abstract: A nucleic acid molecule having a sequence encoding benzoyl-glycine aminohydrolase, commonly known as hippuricase, of Camplylobacter jejuni is provided. Methods are disclosed for detecting C. jejuni in a biological sample by determining the presence of hippuricase or a nucleic acid molecule encoding hippuricase in the sample.
    Type: Grant
    Filed: May 9, 1997
    Date of Patent: January 11, 2000
    Inventors: Voon Loong Chan, Eric Kurt Hani
  • Patent number: 5981189
    Abstract: A nucleic acid molecule having a sequence encoding benzoyl-glycine aminohydrolase, commonly known as hippuricase, of Campylobacter jejuni is provided. Methods are disclosed for detecting C. jejuni in a biological sample by determining the presence of hippuricase or a nucleic acid molecule encoding hippuricase in the sample.
    Type: Grant
    Filed: January 6, 1998
    Date of Patent: November 9, 1999
    Inventors: Voon Loong Chan, Eric Kurt Hani
  • Patent number: 5827654
    Abstract: Purified and isolated nucleic acid molecules are provided which encode a basal body rod protein of a strain of Campylobacter, particularly C. jejuni, or a fragment or an analog of the basal body rod protein. The nucleic acid molecules may be used to produce proteins free of contaminants derived from bacteria normally containing the FlgF or FlgG proteins for purposes of diagnostics and medical treatment. Furthermore, the nucleic acid molecules, proteins encoded thereby and antibodies raised against the proteins, may be used in the diagnosis of infection.
    Type: Grant
    Filed: May 8, 1995
    Date of Patent: October 27, 1998
    Assignee: University of Toronto
    Inventors: Voon Loong Chan, Helena Louie
  • Patent number: 5695960
    Abstract: A nucleic acid molecule having a sequence encoding benzoyl-glycine aminohydrolase, commonly known as hippuricase, of Campylobacter jejuni is provided. Methods are disclosed for detecting C. jejuni in a biological sample by determining the presence of hippuricase or a nucleic acid molecule encoding hippuricase in the sample.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: December 9, 1997
    Inventors: Voon Loong Chan, Eric Kurt Hani