Abstract: Cells may be grown in a bioreactor, and the cells may be activated by an activator (e.g., a soluble activator complex). Nutrient and gas exchange capabilities of a closed, automated cell expansion system may allow cells to be seeded at reduced cell seeding densities, for example. Parameters of the cell growth environment may be manipulated to load the cells into a particular position in the bioreactor for the efficient exchange of nutrients and gases. System parameters may be adjusted to shear any cell colonies that may form during the expansion phase. Metabolic concentrations may be controlled to improve cell growth and viability. Cell residence in the bioreactor may be controlled. In embodiments, the cells may include T cells. The cells may include T cell subpopulations, including regulatory T cells (Tregs), for example.

Abstract: A computer system is structured to determine a density of particulate matter in a diesel particulate filter (DPF) sample. The computer system includes a processing circuit having a processor and a memory. The processing circuit is structured to generate a computed tomography (CT) scan-based image of the DPF sample; and, segment the CT scan-based image of the DPF sample into a plurality of regions. For at least one region from the plurality of regions, the processing circuit is structured to determine a density of a portion of the DPF sample corresponding to the at least one region of the CT scan-based image of the DPF sample and cause an electronic display of a user device to display the CT scan-based image including the at least one region and an indication of the density for the at least one region.

Abstract: A system includes a controller for an exhaust aftertreatment system including a SCR catalyst in exhaust gas-receiving communication with an engine and at least one reductant dosing system structured to provide reductant to the exhaust gas. The controller is structured to determine a ratio of NO to NO2 at or proximate an inlet of the SCR catalyst. The controller is further structured to command the at least one reductant dosing system to increase, decrease, or maintain an amount of reductant provided to the exhaust gas based on comparing the ratio of NO to NO2 to a previous NO to NO2 ratio.

Abstract: A method for functionalizing a hollow-fiber membrane for cell expansion of targeted cells (e.g., natural killer cells) includes contacting a biotinylating molecule to a surface of the hollow-fiber membrane including an extracellular matrix component, the biotinylating molecule binding to the extracellular matrix component and having an affinity for the targeted cells. The biotinylated molecule may be selected from the group consisting of: cytokine, epitope, ligand, monoclonal antibody, stains, aptamer, and combinations thereof. The extracellular matrix component may be selected from the group consisting of: fibronectin, vitronectin, fibrinogen, collagen, laminin, and combinations thereof.

Abstract: The present Application discloses a trenching device with two operational modes, Mode 1 and mode 2. In Mode 1, the trenching lever is disengaged, the device does not trench, but only functions as a transporting unit in a forward direction with a maximum speed. In Mode 2, the trenching lever is engaged, the device starts trenching, but stops functioning as a transporting unit.

Abstract: A technology is described for direction finding. An example of the technology can include executing stages of an N stage search for a direction finding estimate of a plane wave X. The stages of the N stage search include searching a search space in a calibration set having a plurality of points in space and calculating a direction finding estimate, wherein a first search space is a coarse set of points in space and subsequent search spaces selected for subsequent stages of the N stage search are increasingly finer sets of points in the space, and a solution for the direction finding estimate output by a stage of the N stage search is used to select a next search space for a next stage of the N stage search. A direction finding estimate output by a final stage of the N stage search is the final direction finding estimate.

Abstract: A technology is described for direction finding. An example of the technology can include executing stages of an N stage search for a direction finding estimate of a plane wave X. The stages of the N stage search include searching a search space in a calibration set having a plurality of points in space and calculating a direction finding estimate, wherein a first search space is a coarse set of points in space and subsequent search spaces selected for subsequent stages of the N stage search are increasingly finer sets of points in the space, and a solution for the direction finding estimate output by a stage of the N stage search is used to select a next search space for a next stage of the N stage search. A direction finding estimate output by a final stage of the N stage search is the final direction finding estimate.

Abstract: The disclosed invention is embodied in an improved LED-based lighting fixture for projecting a beam of light having a substantially uniform intensity, rotationally, and a selectable, substantially uniform chromaticity. The lighting fixture includes (1) a concave reflector having circumferential facets, a focal region, an aperture, and a central opening; and (2) a light source assembly including two or more groups of LEDs mounted at the forward end of an elongated, thermally conductive support. The light source assembly is mounted relative to the reflector with the elongated support's longitudinal axis aligned with the reflector's longitudinal axis and with the groups of LEDs located at or near the reflector's focal region. Each of the two or more groups of LEDs includes a plurality of LEDs arranged in a specific pattern such that they cooperate with the faceted concave reflector to project a beam of light having a selectable, substantially uniform chromaticity.

Abstract: The disclosed invention is embodied in an improved LED-based lighting fixture for projecting a beam of light having a substantially uniform intensity, rotationally, and a selectable, substantially uniform chromaticity. The lighting fixture includes (1) a concave reflector having circumferential facets, a focal region, an aperture, and a central opening; and (2) a light source assembly including two or more groups of LEDs mounted at the forward end of an elongated, thermally conductive support. The light source assembly is mounted relative to the reflector with the elongated support's longitudinal axis aligned with the reflector's longitudinal axis and with the groups of LEDs located at or near the reflector's focal region.

Abstract: The disclosed invention is embodied in an improved LED-based lighting fixture for projecting a beam of light having a substantially uniform intensity, rotationally, and a selectable, substantially uniform chromaticity. The lighting fixture includes (1) a concave reflector having circumferential facets, a focal region, an aperture, and a central opening; and (2) a light source assembly including two or more groups of LEDs mounted at the forward end of an elongated, thermally conductive support. The light source assembly is mounted relative to the reflector with the elongated support's longitudinal axis aligned with the reflector's longitudinal axis and with the groups of LEDs located at or near the reflector's focal region.

Abstract: The disclosed invention is embodied in an improved LED-based lighting fixture for projecting a beam of light having a substantially uniform intensity, rotationally, and a selectable, substantially uniform chromaticity. The lighting fixture includes (1) a concave reflector having circumferential facets, a focal region, an aperture, and a central opening; and (2) a light source assembly including two or more groups of LEDs mounted at the forward end of an elongated, thermally conductive support. The light source assembly is mounted relative to the reflector with the elongated support's longitudinal axis aligned with the reflector's longitudinal axis and with the groups of LEDs located at or near the reflector's focal region. Each of the two or more groups of LEDs includes a plurality of LEDs arranged in a specific pattern such that they cooperate with the faceted concave reflector to project a beam of light having a selectable, substantially uniform chromaticity.

Abstract: The present Application discloses a trenching device with two operational modes, Mode 1 and mode 2. In Mode 1, the trenching lever is disengaged, the device does not trench, but only functions as a transporting unit in a forward direction with a maximum speed. In Mode 2, the trenching lever is engaged, the device starts trenching, but stops functioning as a transporting unit.

Abstract: A holder for a personal computing device (PCD) and method for allowing a user of a PCD to securely hold the PCD with a single finger; to selectively position his or her thumb horizontally, vertically, angularly, and a desired distance away from the PCD, when holding the PCD to more easily reach any point on the touchscreen with the thumb on his same hand without ever needing to resort to using his other hand; and allowing the user, in the alternative, to rest the PCD on a flat surface, such as to read articles or watch videos, and prop the PCD up at a multitude of angles, in both landscape and portrait orientations depending on whether the flat surface is high or low and whether the user is sitting or standing.

Abstract: Methods and systems for assessing changes to a region are disclosed. An example method can comprise receiving elevation data indicative of a region. A method can comprise generating a spatial model of the region based on the elevation data. A method can also comprise identifying based on the spatial model a first representation of a portion the region. The first representation of the portion of the region can be indicative of the portion of the region at a first time. A method can further comprise determining a difference between the first representation of the portion of the region and a second representation of the portion of the region. The second representation of the portion of the region can be indicative of the portion of the region at a second time.

Abstract: A drillable oilfield tubular plug that employs clutch faces, drilling features, anti-rotation features, and composite materials to facilitate quicker drill-out operations after the plugs have been utilized.