Patents by Inventor W. J. A. VandenHeuvel

W. J. A. VandenHeuvel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oxidized analogs of 17.beta.-N-monosubstituted-carbamoyl-4-aza-5-.alpha.-androstan-3-ones
    Patent number: 4845104
    Abstract: The compounds of formula (I) ##STR1## wherein R is selected from hydrogen, methyl or ethyl, and R.sup.1 is C.sub.1-12 straight or branched chain alkyl wherein one of the hydrogens is substituted by hydroxy, carboxylic acid or C.sub.1-4 alkyl ester, and A is --CH.sub.2 --CH.sub.2 or --CH.dbd.CH--, and pharmaceutical formulations of the above compounds are active as testosterone 5.alpha.-reductase inhibitors and thus are useful for treatment of acne, seborrhea, female hirsutism or benign prostatic hypertrophy.
    Type: Grant
    Filed: November 20, 1986
    Date of Patent: July 4, 1989
    Assignee: Merck & Co., Inc.
    Inventors: Josephine R. Carlin, Gary H. Rasmusson, W. J. A. VandenHeuvel