Patents by Inventor Waleed S. W. Shalaby

Waleed S. W. Shalaby has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bioactive absorbable microparticles as therapeutic vaccines
    Publication number: 20030124149
    Abstract: A therapeutic vaccine for tumor immunotherapy is disclosed which comprises absorbable microparticles/nanoparticles capable of delivering immobilized stimulatory/costimulatory signals and releasing necessary cytokines to promote an anti-tumor effect. The microparticles/nanoparticles are formed of an absorbable crystalline polymer, preferably acid-terminated polyglycolide. Other bioactive agents such as tumor specific antigens, DNA or RNA may be immobilized of the surface of the particles.
    Type: Application
    Filed: July 8, 2002
    Publication date: July 3, 2003
    Inventors: Shalaby W. Shalaby, Waleed S.W. Shalaby, Edward Y. Woo, Heidi Yeh, Carl H. June
  • Multifaceted compositions for post-surgical adhesion prevention
    Patent number: 6551610
    Abstract: This invention deals with an absorbable, gel-forming composition for multifaceted prevention of post-operative surgical adhesion through a plurality of physico-pharmacological modes, comprising a solution of one or more bioactive compounds in a liquid copolymeric vehicle made by end-grafting one or more cyclic monomer onto a polyalkylene glycol. More specifically, the bioactive drugs can display one or more pharmacological activity associated with antiangiogenic, antineoplastic, anti-inflammatory, and anti-proliferative effects.
    Type: Grant
    Filed: April 24, 2002
    Date of Patent: April 22, 2003
    Assignee: Poly-Med, Inc.
    Inventors: Shalaby W. Shalaby, Waleed S. W. Shalaby, Marc Shalaby
  • Multifaceted compositions for post-surgical adhesion prevention
    Publication number: 20020164365
    Abstract: This invention deals with an absorbable, gel-forming composition for multifaceted prevention of post-operative surgical adhesion through a plurality of physico-pharmacological modes, comprising a solution of one or more bioactive compounds in a liquid copolymeric vehicle made by end-grafting one or more cyclic monomer onto a polyalkylene glycol. More specifically, the bioactive drugs can display one or more pharmacological activity associated with antiangiogenic, antineoplastic, anti-inflammatory, and anti-proliferative effects.
    Type: Application
    Filed: April 24, 2002
    Publication date: November 7, 2002
    Inventors: Shalaby W. Shalaby, Waleed S.W. Shalaby, Marc Shalaby
  • Oral administration of antigens
    Patent number: 5352448
    Abstract: An oral vaccine formulation is provided for stimulation of an immune response in gut-associated lymphoid tissues. The formulation comprises an enzymatically degradable antigen in a hydrogel matrix. In ruminant species, the vaccine formulation, upon oral administration, is formed to pass through the rumen without substantial hydration and then into the post-ruminal portion of the digestive tract where the antigen is released for contact with the gut-associated lymphoid tissue.
    Type: Grant
    Filed: July 20, 1992
    Date of Patent: October 4, 1994
    Assignee: Purdue Research Foundatioin
    Inventors: Terry L. Bowersock, Waleed S. W. Shalaby, William E. Blevins, Michel Levy, Kinam Park