Abstract: The invention is directed to a method for performing a high throughput test to determine the presence of PrPsc in a tissue sample taken post mortem from brain, the test comprising the workflow of (A) sample preparation, (B) sample treatment, (C) sample analysis, (D) controls, and (E) classifying the results of the analysis as positive or negative. The invention is further directed to preparing a treated biological sample suspected of containing PrPsc such that it is suitable for specific detection of PrPsc, if present, the method comprising the steps of (a) homogenizing the sample; followed by (b) digesting the sample proteolytically by adding to the homogenate Proteinase K and incubating the sample; followed by (c) adding a peptidic protease inhibitor to the incubated mixture of step (b), thereby obtaining a treated biological sample suitable for specific detection of PrPsc, if present. The invention further provides a conditioned microwell plate.

Abstract: The present invention relates to a device for separating a tissue part from brain material, said device comprising a circular blade which continues as the wall of a cylindrical or substantially cylindrical hollow body, at the end of which a grid is arranged perpendicular to the cylinder axis. The invention further relates to the use of the device in a method for separating a tissue part from brain material and to a kit containing one or more devices according to the invention.

Abstract: The invention relates to a method for actuating a reversible belt pretensioner for pretensioning a belt webbing, wound around a belt reel, of a seat belt in a motor vehicle, the belt pretensioner having a drive which acts on the belt reel. The seat belt has a locking device, acting on the belt reel in the unwinding direction, as a belt extraction lock. After the triggering of the belt pretensioner and when a predefinable condition is met, the belt pretensioner is actuated in such a way that the belt reel rotates at least to such an extent in the winding-up direction that the locking device of the belt reel opens and releases the belt webbing for unwinding.

Abstract: The invention relates to a method for actuating a reversible vehicle occupant protection means in a motor vehicle having a driving state sensor system and a reversible vehicle occupant protection means. The reversible vehicle occupant protection means can be triggered before the collision time and as a result moved into an effective position. For this purpose, the driving state data are monitored with respect to a state of emergency braking, and when the state of emergency braking is detected the vehicle occupant protection system is actuated. In addition, a state of oversteering and a state of understeering are determined by the data processing device. The reversible vehicle occupant protection system is actuated when the data processing device detects the state of emergency braking and/or the state of oversteering and/or the state of understeering.

Abstract: Method for actuating a reversible belt pretensioner for pretensioning a belt webbing, unwound from a belt reel, of a seat belt in a motor vehicle, the belt pretensioner having a drive which acts on the belt reel, and the seat belt having, as a belt extraction lock, a locking device which acts on the belt reel in the unwinding direction and whose locking can be released only if the belt reel is rotated about a certain angle of rotation in the winding-on direction. After a triggering of the belt pretensioner caused by a hazardous situation and if a variable indicative of the belt force indicates a decrease in the belt force, an opening mode is initiated in which the belt pretensioner drive is actuated in order to open the blocking device in such a manner that, at the beginning of the opening mode, the belt reel rotates about the specific angle of rotation in the winding-on direction.

Abstract: A method for moving a head restraint of a vehicle seat in the event of a rear-end collision and an arrangement of a head restraint on a vehicle seat are provided. In the event of a rear-end collision, the head restraint can be moved in the forward direction of travel by a drive device, and an impact device absorbs a rearward movement of an upper body of an occupant located on the vehicle seat.

Abstract: A belt tightener of a seat belt in a vehicle, in particular a motor vehicle, is provided with a retracting spring in order to return the belt. A counterspring, which can be adjusted by a motor, is connected in parallel with the retracting spring in order to be able to reduce the tensile force of the belt for comfort considerations. The motor can also be connected in drive terms to the belt via a coupling arrangement to give reversible belt tightening.

Abstract: In a belt tensioner of a seat belt in a vehicle, particularly a motor vehicle, for the return movement of the belt, a return spring is provided which is able to be tensioned by a motor as a function of parameters. The motor may also be used for a reversible tightening of the belt.

Abstract: In a belt tensioner of a seat belt in a vehicle, in particular a motor vehicle, a retraction device, which is driven by a motor and has a retraction force that is controllable as a function of parameters, is provided for retracting the belt.

Abstract: A method for actuating a reversible vehicle occupant protection device in a motor vehicle having a driving state sensor system and a reversible vehicle occupant protection device. The reversible vehicle occupant protection device can be triggered before the collision time and as a result moved into an effective position. For this purpose, the driving state data are monitored with respect to a state of emergency braking, and when the state of emergency braking is detected the vehicle occupant protection system is actuated. In addition, a state of oversteering and a state of understeering are determined by the data processing device. The reversible vehicle occupant protection system is actuated when the data processing device detects the state of emergency braking and/or the state of oversteering and/or the state of understeering.

Abstract: A method and system for restraining an occupant on a vehicle seat, the occupant being pulled into the vehicle seat is provided with a force by a belt tensioner when a critical driving state is detected and then held in a pulled-back position on the vehicle seat with a holding force. The holding force selected is lower than the force for pulling the occupant back. A forward-looking detection system for a dangerous driving state and an occupant-position detection system unprovided, in which, when a dangerous driving state is detected, a belt tensioner is subjected to a force and the occupant is thereby pulled into the vehicle seat, and in which the occupant is held in a pulled-back position on the vehicle seat with a holding force which is lower than the force for pulling the occupant back.

Abstract: Method for actuating a reversible belt pretensioner for pretensioning a belt webbing, unwinding from a belt reel, of a seat belt in a motor vehicle, the belt pretensioner having a drive which acts on the belt reel, and the seat belt having, as a belt extraction lock, a locking device which acts on the belt reel in the unwinding direction and whose locking can be released only if the belt reel is rotated through a specific angle of rotation in the winding-on direction. After the triggering of the belt pretensioner, the drive of the belt pretensioner for opening the locking device is actuated in an opening mode in such a way that firstly, in a winding-on phase, the belt reel rotates through the specific angle of rotation in the winding-on direction. In a subsequent holding phase, the drive of the belt pretensioner is actuated for a predefinable holding time TH in such a way that the belt reel is held in its angular position.

Abstract: The invention relates to a hazard-prevention system for a vehicle. The vehicle has devices for sensing driving state variables, for sensing ambient data and for sensing the driver's activity, and a data processing device. The data processing device is provided for processing the sensed data and for actuating a safety device in accordance with a predefined control strategy. According to the invention, the vehicle has a device for identifying the driver, and the data processing device derives a driver load factor related specifically to the driver from the driving state variables, the ambient data and the data relating to the activity of the driver, and said driver load factor is used to adapt the control strategy.

Abstract: The invention relates to a method for actuating a reversible belt pretensioner for pretensioning a belt webbing, wound around a belt reel, of a seat belt in a motor vehicle, the belt pretensioner having a drive which acts on the belt reel. The seat belt has a locking device, acting on the belt reel in the unwinding direction, as a belt extraction lock. According to the invention, after the triggering of the belt pretensioner and when a predefinable condition is met, the belt pretensioner is actuated in such a way that the belt reel rotates at least to such an extent in the winding-up direction that the locking device of the belt reel opens and releases the belt webbing for unwinding.

Abstract: In a belt tensioner of a seat belt in a vehicle, in particular a motor vehicle, a retraction device, which is driven by a motor and has a retraction force that is controllable as a function of parameters, is provided for retracting the belt.

Abstract: In a belt tensioner of a seat belt in a vehicle, particularly a motor vehicle, for the return movement of the belt, a return spring is provided which is able to be tensioned by a motor as a function of parameters. The motor may also be used for a reversible tightening of the belt.

Abstract: A belt tightener of a seat belt in a vehicle, in particular a motor vehicle, is provided with a retracting spring in order to return the belt. A counterspring, which can be adjusted by a motor, is connected in parallel with the retracting spring in order to be able to reduce the tensile force of the belt for comfort considerations. The motor can also be connected in drive terms to the belt via a coupling arrangement to give reversible belt tightening.

Abstract: A method and system for restraining an occupant on a vehicle seat, the occupant being pulled into the vehicle seat is provided with a force by a belt tensioner when a critical driving state is detected and then held in a pulled-back position on the vehicle seat with a holding force. The holding force selected is lower than the force for pulling the occupant back. A forward-looking detection system for a dangerous driving state and an occupant-position detection system unprovided, in which, when a dangerous driving state is detected, a belt tensioner is subjected to a force and the occupant is thereby pulled into the vehicle seat, and in which the occupant is held in a pulled-back position on the vehicle seat with a holding force which is lower than the force for pulling the occupant back.

Abstract: In a brake control system for mitigating the consequences of an accident in the case of a rear-on collision of a motor vehicle, it is provided that a comparison signal assigned to the positive longitudinal acceleration of the vehicle is determined, that the comparison signal is compared with a threshold value and that, in the event that the comparison signal exceeds the threshold value, a braking signal triggering the vehicle brake is generated.

Abstract: Method of controlling at least one active headrest in a vehicle. The invention relates to a method of controlling an active headrest in a vehicle, in which the active headrest is triggered when predeterminable triggering conditions indicative of a vehicle collision exist, comprising the exceeding of a predeterminable collision threshold value by a characteristic variable indicative of a collision.