Patents by Inventor Walter H. Chang

Walter H. Chang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of gold nanoclusters in ameliorating oxidate stress and/or aging
    Patent number: 9101672
    Abstract: Disclosed herein is the novel use of a gold nanocluser for ameliorating oxidative stress and/or aging of a cultured cell or a subject having an oxidative stress and/or aging condition mediated by a vascular factor. The gold nanocluster has a particle size ranging from about 0.1 to 20 nm, and preferably is dihydrolipoic acid (DHLA) coated gold nanocluster.
    Type: Grant
    Filed: August 26, 2011
    Date of Patent: August 11, 2015
    Assignees: MACKAY MEMORIAL HOSPITAL, CHUNG YUAN CHRISTIAN UNIVERSITY
    Inventors: Hung-I Yeh, Walter H. Chang, Cheng-An Lin, Hsueh-Hsiao Wang
  • Method for forming nano-bubble
    Patent number: 8974770
    Abstract: The present invention discloses a method for forming a nano-bubble. The forming method is different from the oil-water emulsion reaction in the prior art. The method comprises: taking an inorganic particle as a nucleus and performing a polymer coating process to coat at least one first polymer on the surface of the nucleus to form an organic/inorganic composite particle; then removing the nucleus of the organic/inorganic composite particle by way of the dissolution of a first solvent to form an impregnated nano-particle; performing a freeze-drying process to remove the first solvent to have the impregnated nano-particle form a hollow nano-particle; and finally dissolving the hollow nano-particle in a second solvent to form the nano-bubble.
    Type: Grant
    Filed: April 15, 2009
    Date of Patent: March 10, 2015
    Assignee: Chung Yuan Christian University
    Inventors: Walter H. Chang, Cheng-An Lin, Chih-Hsien Lee, Chih-Kuang Yeh
  • Use of Gold Nanoclusters in Ameliorating Oxidate Stress and/or Aging
    Publication number: 20130052270
    Abstract: Disclosed herein is the novel use of a gold nanocluser for ameliorating oxidative stress and/or aging of a cultured cell or a subject having an oxidative stress and/or aging condition mediated by a vascular factor. The gold nanocluster has a particle size ranging from about 0.1 to 20 nm, and preferably is dihydrolipoic acid (DHLA) coated gold nanocluster.
    Type: Application
    Filed: August 26, 2011
    Publication date: February 28, 2013
    Applicants: CHUNG YUAN CHRISTIAN UNIVERSITY, MACKAY MEMORIAL HOSPITAL
    Inventors: Hung-I Yeh, Walter H. Chang, Cheng-An Lin, Hsueh-Hsiao Wang
  • Tunable Fluorescent Gold Nanocluster
    Publication number: 20120241673
    Abstract: The present invention discloses a tunable fluorescent gold nanocluster. The tunable fluorescent gold nanocluster is formed by mixing gold trichloride (AuCl3) with toluene solvent without reductant. The tunable fluorescent gold nanocluster emits blue fluorescence that can be red shifted through ultrasonic vibration. The spectral region of the tunable fluorescent gold nanocluster is from 400 nm to 550 nm.
    Type: Application
    Filed: April 30, 2012
    Publication date: September 27, 2012
    Applicant: CHUNG YUAN CHRISTIAN UNIVERSITY
    Inventors: Walter H. Chang, Cherng-Jyh Ke, Cheng-An Lin, Ching-Yun Chen
  • Tunable Fluorescent Gold Nanocluster And Method for forming the same
    Publication number: 20100163806
    Abstract: The present invention discloses a tunable fluorescent gold nanocluster. The tunable fluorescent gold nanocluster is formed by mixing gold trichloride (AuCl3) with toluene solvent without reductant. The tunable fluorescent gold nanocluster emits blue fluorescence that can be red shifted through ultrasonic vibration. The spectral region of the tunable fluorescent gold nanocluster is from 400 nm to 550 nm.
    Type: Application
    Filed: July 8, 2009
    Publication date: July 1, 2010
    Applicant: CHUNG YUAN CHRISTIAN UNIVERSITY
    Inventors: Walter H. Chang, Cherng-Jyh Ke, Cheng-An Lin, Ching-Yun Chen
  • Method for Forming Nano-bubble
    Publication number: 20100080759
    Abstract: The present invention discloses a method for forming a nano-bubble. The forming method is different from the oil-water emulsion reaction in the prior art. The method comprises: taking an inorganic particle as a nucleus and performing a polymer coating process to coat at least one first polymer on the surface of the nucleus to form an organic/inorganic composite particle; then removing the nucleus of the organic/inorganic composite particle by way of the dissolution of a first solvent to form an impregnated nano-particle; performing a freeze-drying process to remove the first solvent to have the impregnated nano-particle form a hollow nano-particle; and finally dissolving the hollow nano-particle in a second solvent to form the nano-bubble.
    Type: Application
    Filed: April 15, 2009
    Publication date: April 1, 2010
    Applicant: CHUNG YUAN CHRISTIAN UNIVERSITY
    Inventors: Walter H. Chang, Cheng-An Lin, Chih-Hsien Lee, Chih-Kuang Yeh