Abstract: An anti-septic dispensing device allows items, such as gloves, to be reliably removed one at a time from a container while limiting the risk for contamination of the items and/or transmission of infectious agents to the items during removal. The device has a plurality of panels that define a space for receiving one or more containers. One panel contains an aperture aligned with an opening in the container received in the space. A flexible sheet is arranged surrounding the aperture in the one panel. The flexible sheet includes a passage that provides reach-in access to the items. The anti-septic dispensing device includes an antimicrobial component on the flexible sheet and/or the panels. The antimicrobial component limits the potential for transmission of infections agents during the item removal process.