Patents by Inventor Walter L. Tien

Walter L. Tien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CYCLOSPORIN COMPOSITIONS
    Publication number: 20220409693
    Abstract: Disclosed herein are therapeutic methods, compositions, and medicaments related to cyclosporine.
    Type: Application
    Filed: May 12, 2022
    Publication date: December 29, 2022
    Inventors: Richard S. Graham, Walter L. Tien, Mayssa Attar, Rhett Schiffman, Aileen Morgan
  • CYCLOSPORIN COMPOSITIONS
    Publication number: 20210169971
    Abstract: Disclosed herein are therapeutic methods, compositions, and medicaments related to cyclosporine.
    Type: Application
    Filed: October 7, 2020
    Publication date: June 10, 2021
    Inventors: Richard S. Graham, Walter L. Tien, Mayssa Attar, Rhett (Last name not provided), Aileen Morgan
  • CYCLOSPORIN COMPOSITIONS
    Publication number: 20170143792
    Abstract: Disclosed herein are therapeutic methods, compositions, and medicaments related to cyclosporine.
    Type: Application
    Filed: February 6, 2017
    Publication date: May 25, 2017
    Inventors: Richard S. Graham, Walter L. Tien, Mayssa Attar, Rhett M. Schiffman, Aileen Morgan
  • Cyclosporin compositions
    Patent number: 9561178
    Abstract: Disclosed herein are therapeutic methods, compositions, and medicaments related to cyclosporine.
    Type: Grant
    Filed: July 20, 2007
    Date of Patent: February 7, 2017
    Assignee: Allergan, Inc.
    Inventors: Richard S. Graham, Walter L. Tien, Mayssa Attar, Rhett Schiffman, Aileen Morgan
  • Pharmaceutical compositions comprising cyclosporins
    Patent number: 8906861
    Abstract: A composition is described herein comprising cyclosporin A, polysorbate 80, a polyoxyethylene stearate, and an oil; wherein the composition is an emulsion which is ophthalmically acceptable. Methods of treating diseases or conditions using said compositions, and medicaments related thereto, are also disclosed herein.
    Type: Grant
    Filed: January 28, 2009
    Date of Patent: December 9, 2014
    Assignee: Allergan, Inc.
    Inventors: Walter L. Tien, Richard S. Graham, James N. Chang
  • PRESERVED TOPICAL FORMULATIONS WITH IMPROVED ANTIMICROBIAL ACTIVITY
    Publication number: 20140127327
    Abstract: A preservative consisting of a stabilized oxychloro complex and a polyol having from 3 to 6 carbons is disclosed herein. A composition comprising a stabilized chlorine dioxide. and a polyol having from 3 to 6 carbons is also disclosed herein.
    Type: Application
    Filed: November 6, 2013
    Publication date: May 8, 2014
    Applicant: Allergan, Inc.
    Inventors: Richard S. Graham, Walter L. Tien
  • COMBINATIONS OF PRESERVATIVES FOR OPHTHALMIC COMPOSITIONS
    Publication number: 20110251285
    Abstract: The present invention provides a preservative composition for protecting ophthalmic solutions from microbial attack comprising a combination of benzalkonium ion and polyhexamethylene biguanide (PHMB) wherein the combined concentrations of benzalkonium ion and polyhexamethylene biguanide (PHMB) in said composition is sufficient to provide protection against microbial attack when said composition is added to an ophtalmic solution as compared to said ophthalmic soulution having the same concentration of benzalkonium ion and polyhexamethylene biguanide (PHMB), alone.
    Type: Application
    Filed: April 6, 2011
    Publication date: October 13, 2011
    Applicant: ALLERGAN, INC.
    Inventors: Walter L. Tien, Richard S. Graham, Ramakrishnan Srikumar
  • COMBINATIONS OF PRESERVATIVE COMPOSITIONS FOR OPHTHALMIC FORMULATIONS
    Publication number: 20110250294
    Abstract: The present invention provides a preservative composition for protecting ophthalmic solutions from microbial attack comprising a combination of benzalkonium ion and An oxy-chlorite moiety, e.g. purite wherein the combined concentrations of benzalkonium ion and An oxy-chlorite moiety, e.g. purite in said composition is sufficient to provide protection against microbial attack when said composition is added to an ophthalmic solution as compared to said ophthalmic solution having the same concentration of benzalkonium ion and An oxy-chlorite moiety, e.g. purite, alone.
    Type: Application
    Filed: April 6, 2011
    Publication date: October 13, 2011
    Applicant: ALLERGAN, INC.
    Inventors: Walter L. Tien, Richard S. Graham, Ramakrishnan Srikumar
  • PHARMACEUTICAL COMPOSITIONS COMPRISING CYCLOSPORINS
    Publication number: 20090131307
    Abstract: A composition is described herein comprising cyclosporin A, polysorbate 80, a polyoxyethylene stearate, and an oil; wherein the composition is an emulsion which is ophthalmically acceptable. Methods of treating diseases or conditions using said compositions, and medicaments related thereto, are also disclosed herein.
    Type: Application
    Filed: January 28, 2009
    Publication date: May 21, 2009
    Inventors: Walter L. Tien, Richard Graham, James N. Chang
  • Pharmaceutical compositions comprising cyclosporins
    Patent number: 7501393
    Abstract: A composition is described herein comprising cyclosporin A, polysorbate 80, a polyoxyethylene stearate, and an oil; wherein the composition is an emulsion which is ophthalmically acceptable. Methods of treating diseases or conditions using said compositions, and medicaments related thereto, are also disclosed herein.
    Type: Grant
    Filed: July 27, 2005
    Date of Patent: March 10, 2009
    Assignee: Allergan, Inc.
    Inventors: Walter L. Tien, Richard Graham, James N. Chang
  • CYCLOSPORIN COMPOSITIONS FOR OCULAR ROSACEA TREATMENT
    Publication number: 20080207495
    Abstract: Disclosed herein are methods of treating ocular rosacea with cyclosporin A. Compositions and medicaments related thereto are also disclosed.
    Type: Application
    Filed: February 22, 2008
    Publication date: August 28, 2008
    Inventors: Richard S. Graham, Walter L. Tien, Mayssa Attar, Rhett Schiffman, Michael E. Stern, Robin Sears, John G. Walt, Tamara Cassaro
  • Cyclosporin Compositions
    Publication number: 20080146497
    Abstract: Disclosed herein are therapeutic methods, compositions, and medicaments related to cyclosporine.
    Type: Application
    Filed: September 20, 2007
    Publication date: June 19, 2008
    Inventors: Richard S. Graham, Walter L. Tien, Mayssa Attar, Rhett Schiffman, Aileen Morgan, David A. Hollander
  • Method for reducing filtrate waste in a manufacturing process of a pharmaceutical product containing benzalkonium chloride
    Patent number: 5550163
    Abstract: A method for reducing filtrate waste in a manufacturing process of a pharmaceutical product containing benzalkonium chloride as a preservative generally includes the steps of mixing the non-benzalkonium chloride components with benzalkonium chloride to formulate the product and thereafter sterilizing the product by passing same through a microfiltration membrane. In processes in which the product has a time dependent benzalkonium chloride content due to benzalkonium chloride adsorption on a microfiltration membrane, an amount of benzalkonium chloride wasted can be reduced by maintaining a selected temperature of the microfiltration membrane and the product therein.
    Type: Grant
    Filed: August 3, 1994
    Date of Patent: August 27, 1996
    Assignee: Allergan, Inc.
    Inventors: Shulin Ding, Robert J. Pallo, Walter L. Tien, Orest Olejnik
  • Nonirritating emulsions for sensitive tissue
    Patent number: 5474979
    Abstract: A pharmaceutical composition is disclosed in the form of a nonirritating emulsion which includes at least one cyclosporin in admixture with a higher fatty acid glyceride and polysorbate 80. More particularly, the cyclosporin may be cyclosporin A and the higher fatty acid glyceride may be castor oil. Composition has been found to be of a high comfort level and low irritation potential suitable for delivery of medications to sensitive areas such as ocular tissues. In addition, the composition has stability for up to nine months without crystallization of cyclosporin.
    Type: Grant
    Filed: May 17, 1994
    Date of Patent: December 12, 1995
    Assignee: Allergan, Inc.
    Inventors: Shulin Ding, Walter L. Tien, Orest Olejnik