Patents by Inventor Walter Spevak

Walter Spevak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted indolinones, preparation thereof and their use as pharmaceutical compositions
    Patent number: 6638965
    Abstract: Indolinones of general formula I which are inhibitors of cell proliferation, particularly of tumour cells, and inhibitors of protein kinases. The following compounds are exemplary: (Z)-3-{1-[4-(N-(2-aminoethyl)-N-methylsulphonyl-amino)-phenylamino]-1-phenyl-methylidene}-5-phenylsulphonylamino-2-indolinone, (Z)-3-{1-[4-(N-(2-dimethylaminoethyl)-N-phenylsulphonyl-amino)-phenylamino]-1-phenyl-methylidene}-5-phenylsulphonylamino-2-indolinone, and (Z)-3-{1-[4-(4-methylpiperazinomethyl)-phenylamino]-1-phenyl-methylidene}-5-phenylsulphonylamino-2-indolinone.
    Type: Grant
    Filed: November 1, 2001
    Date of Patent: October 28, 2003
    Assignee: Boehringer Ingelheim Pharma KG
    Inventors: Rainer Walter, Armin Heckel, Gerald Roth, Joerg Kley, Gisela Schnapp, Martin Lenter, Jacobus Van Meel, Walter Spevak, Ulrike Weyer-Czernilofsky
  • Pyrimidine derivatives
    Publication number: 20030171359
    Abstract: The present invention relates to trisubstituted pyrimidines of formula (I) 1
    Type: Application
    Filed: October 16, 2002
    Publication date: September 11, 2003
    Applicant: Boehringer Ingelheim Pharma KG
    Inventors: Georg Dahmann, Frank Himmelsbach, Bernd Krist, Martin Lenter, Alexander Pautsch, Gisela Schnapp, Martin Steegmaier, Helmut Wittneben, Anthony S. Prokopowicz, Walter Spevak, Andreas Schoops, Steffen Steurer
  • Substituted indolinones, preparation thereof and their use as pharmaceutical compositions
    Publication number: 20030069299
    Abstract: Indolinones of general formula I 1
    Type: Application
    Filed: November 1, 2001
    Publication date: April 10, 2003
    Inventors: Rainer Walter, Armin Heckel, Gerald Roth, Joerg Kley, Gisela Schnapp, Martin Lenter, Jacobus Van Meel, Walter Spevak, Ulrike Weyer-Czernilofsky
  • Human lysozyme
    Patent number: 5618712
    Abstract: This invention relates to a process for preparing human lysozyme and the human lysozyme protein itself.
    Type: Grant
    Filed: April 4, 1994
    Date of Patent: April 8, 1997
    Assignee: Boehringer Ingelheim Zentrale GmbH
    Inventors: Andrzej Sledziewski, Ewa Chlebowicz-Sledziewska, Peter Swetly, Gunther Adolf, Rudolf Hauptmann, Maria J. Castanon, Walter Spevak
  • Human manganese superoxide dismutase (hMn-SOD)
    Patent number: 5589371
    Abstract: The present invention relates to a method of preparing human Mn-superoxide dismutase (hMn-SOD) by genetic engineering, the DNA sequences which code for this enzyme, suitable vectors which contain these DNA sequences and host cells which can express these DNA sequences, and the enzyme hMn-SOD itself. Suggestions as to the use of this enzyme are also described.
    Type: Grant
    Filed: March 30, 1995
    Date of Patent: December 31, 1996
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Konrad Heckl, Walter Spevak, Elinborg Ostermann, Andreas Zophel, Edeltraud Krystek, Ingrid Maurer-Fogy, Maria J. Wiche-Castanon, Christian Stratowa, Rudolf Hauptmann
  • Human manganese superoxide dismutase (hMn-SOD)
    Patent number: 5436162
    Abstract: The present invention relates to a method of preparing human Mn-superoxide dismutase (hMn-SOD) by genetic engineering, the DNA sequences which code for this enzyme, suitable vectors which contain these DNA sequences and host cells which can express these DNA sequences, and the enzyme hMn-SOD itself. Suggestions as to the use of this enzyme are also described.
    Type: Grant
    Filed: September 15, 1992
    Date of Patent: July 25, 1995
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Konrad Heckl, Walter Spevak, Elinborg Ostermann, Andreas Zophel, Edeltraud Krystek, Ingrid Maurer-Fogy, Maria J. Wiche-Castanon, Christian Stratowa, Rudolf Hauptmann
  • Human manganese superoxide dismutase (hMn-SOD)
    Patent number: 5260204
    Abstract: The present invention relates to a method of preparing human Mn-superoxide dismutase (hMn-SOD) by genetic engineering, the DNA sequences which code for this enzyme, suitable vectors which contain these DNA sequences and host cells which can express these DNA sequences, and the enzyme hMn-SOD itself. Suggestions as to the use of this enzyme are also described.
    Type: Grant
    Filed: September 15, 1992
    Date of Patent: November 9, 1993
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Konrad Heckl, Walter Spevak, Elinborg Ostermann, Andreas Zophel, Edeltraud Krystek, Ingrid Maurer-Fogy, Maria J. Wiche-Castanon, Christian Stratowa, Rudolf Hauptmann
  • Human manganese superoxide dismutase (hMn-SOD)
    Patent number: 5240847
    Abstract: The present invention relates to a method of preparing human Mn-superoxide dismutase (hMn-SOD) by genetic engineering, the DNA sequences which code for this enzyme, suitable vectors which contain these DNA sequences and host cells which can express these DNA sequences, and the enzyme hMn-SOD itself. Suggestions as to the use of this enzyme are also described.
    Type: Grant
    Filed: March 11, 1988
    Date of Patent: August 31, 1993
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Konrad Heckl, Walter Spevak, Elinborg Ostermann, Andreas Zophel, Edeltraud Krystek, Ingrid Maurer-Fogy, Maria J. Wiche-Castanon, Christian Stratowa, Rudolf Hauptmann