Patents by Inventor Warren C. MacKellar

Warren C. MacKellar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing anti-obesity protein
    Patent number: 5614379
    Abstract: The present invention is directed to a novel process of preparing an anti-obesity protein using dipeptidyl-aminopeptidase isolated from the cellular slime mold, Dictyostelium discodeum. The process produces an anti-obesity protein in high yield.
    Type: Grant
    Filed: April 26, 1995
    Date of Patent: March 25, 1997
    Assignee: Eli Lilly and Company
    Inventor: Warren C. MacKellar
  • Anti-obesity proteins
    Patent number: 5594101
    Abstract: The present invention provides anti-obesity proteins, which when administered to a patient regulate fat tissue. Accordingly, such agents allow patients to overcome their obesity handicap and live normal lives with much reduced risk for type II diabetes, cardiovascular disease and cancer.
    Type: Grant
    Filed: March 3, 1995
    Date of Patent: January 14, 1997
    Assignee: Eli Lilly and Company
    Inventors: Gerald W. Becker, John E. Hale, Warren C. MacKellar
  • Enzymatic removal of a protein amino-terminal sequence
    Patent number: 5352769
    Abstract: This disclosure relates to new compounds and to a process for the controlled conversion of such compounds to produce a Protein that comprises an amino acid sequence which is useful as a precursor to human insulin or to a modified human insulin, the amino terminus portion of which sequence does not define a cathepsin C dipeptide removal stop point. The compounds have the formula Met-Y-Protein in which Y is Tyr or Arg.
    Type: Grant
    Filed: April 6, 1992
    Date of Patent: October 4, 1994
    Assignee: Eli Lilly and Company
    Inventors: Gerald W. Becker, Thomas C. Furman, Warren C. MacKellar, James P. McDonough
  • Enzymatic removal of a protein amino-terminal sequence
    Patent number: 5126249
    Abstract: This disclosure relates to new compounds and to a process for the controlled conversion of such compounds to produce a Protein that comprises an amino acid sequence which is useful as a precursor to human insulin or to a modified human insulin, the amino terminus portion of which sequence does not define a cathepsin C dipeptide removal stop point. The compounds have the formula Met-Y-Protein in which Y is Tyr or Arg.
    Type: Grant
    Filed: May 9, 1989
    Date of Patent: June 30, 1992
    Assignee: Eli Lilly and Company
    Inventors: Gerald W. Becker, Thomas C. Furman, Warren C. MacKellar, James P. McDonough