Patents by Inventor Warren Kenyon Miller

Warren Kenyon Miller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Colloidal dispersion comprising HPMCAS
    Patent number: 10471152
    Abstract: The present disclosure relates to compositions of an aqueous colloidal dispersion of hydroxypropyl methyl cellulose acetate succinate (HPMCAS), and methods for making such colloidal dispersions.
    Type: Grant
    Filed: August 19, 2015
    Date of Patent: November 12, 2019
    Assignee: Capsugel Belgium NV
    Inventors: Jonathan Leonard Cape, Warren Kenyon Miller, Dwayne Thomas Friesen, Hassan Benameur, Maryline Clauzel, David Thomas Vodak
  • COLLOIDAL DISPERSION COMPRISING HPMCAS
    Publication number: 20170281780
    Abstract: The present disclosure relates to compositions of an aqueous colloidal dispersion of hydroxypropyl methyl cellulose acetate succinate (HPMCAS), and methods for making such colloidal dispersions.
    Type: Application
    Filed: August 19, 2015
    Publication date: October 5, 2017
    Applicant: Capsugel Belgium NV
    Inventors: Jonathan Leonard Cape, Warren Kenyon Miller, Dwayne Thomas Friesen, Hassan Benameur, Maryline Clauzel, David Thomas Vodak
  • Pharmaceutical compositions comprising nanoparticles and a resuspending material
    Patent number: 9724362
    Abstract: A pharmaceutical composition comprises nanoparticles comprising a poorly water-soluble drug and a poorly aqueous soluble polymer, and a resuspending material selected from the group consisting of hydroxypropyl methyl cellulose acetate succinate, carboxymethyl ethylcellulose, and pharmaceutically acceptable salt forms thereof.
    Type: Grant
    Filed: December 5, 2008
    Date of Patent: August 8, 2017
    Assignee: Bend Research, Inc.
    Inventors: Warren Kenyon Miller, Daniel Smithey, Benjamin Lee Frankamp, Ralph Tadday
  • NANOPARTICLE FORMULATIONS OF LOW-WATER SOLUBILITY ACTIVES
    Publication number: 20170209375
    Abstract: Disclosed are compositions including nanoparticles comprising a poorly aqueous soluble polymer, an ionizable active agent, and a counterion having an opposite charge as the ionizable active agent, as well as methods of making and using the compositions.
    Type: Application
    Filed: July 15, 2015
    Publication date: July 27, 2017
    Applicant: Bend Research, Inc.
    Inventors: Warren Kenyon Miller, Michael Mark Morgen
  • N-(4-PHENYL)-N'-(3-FLUOROPHENYL)UREA DOCUSATE
    Publication number: 20170197980
    Abstract: Docusate salts of N-(4-{4-amino-7-[1-(2-hydroxyethyl)-1H-pyrazol-4-yl]thieno[3,2-c]pyridin-3-yl}phenyl)-N?-(3-fluorophenyl)urea are suitable pharmaceutical ingredients for pharmaceutical compositions useful in the treatment of disease, for example, cancer.
    Type: Application
    Filed: June 25, 2015
    Publication date: July 13, 2017
    Inventors: Lloyd S. Dias, Rodney James Ketner, Jonathan M. Miller, Warren Kenyon Miller, Michael Mark Morgen, Brice George Murri, David Thomas Vodak
  • Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glocol succinate
    Patent number: 9545384
    Abstract: A pharmaceutical composition comprises nanoparticles comprising a poorly water soluble drug, a non-ionizable cellulosic polymer, and TPGS.
    Type: Grant
    Filed: May 26, 2008
    Date of Patent: January 17, 2017
    Assignee: Bend Research, Inc.
    Inventor: Warren Kenyon Miller
  • Nanoparticles comprising a non-ionizable polymer and an Amine-functionalized methacrylate copolymer
    Patent number: 9233078
    Abstract: A pharmaceutical composition comprises nanoparticles comprising a poorly water soluble drug, a poorly aqueous soluble non-ionizable polymer, and an amine-functionalized methacrylate copolymer.
    Type: Grant
    Filed: December 5, 2008
    Date of Patent: January 12, 2016
    Assignee: Bend Research, Inc.
    Inventors: Corey J. Bloom, Marshall David Crew, Warren Kenyon Miller
  • Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer
    Patent number: 8974827
    Abstract: A pharmaceutical composition comprises nanoparticles comprising a poorly water-soluble drug, a poorly aqueous soluble non-ionizable cellulosic polymer, and a poorly aqueous soluble polymeric amphiphilic non-ionizable block copolymer.
    Type: Grant
    Filed: May 26, 2008
    Date of Patent: March 10, 2015
    Assignee: Bend Research, Inc.
    Inventors: Corey Jay Bloom, Marshall David Crew, Warren Kenyon Miller, Michael Mark Morgen, Daniel Tod Smithey
  • Solid compositions of low-solubility drugs and poloxamers
    Patent number: 8974823
    Abstract: Solid compositions of low-solubility drugs and poloxamers that provide concentration enhancement when administered to an aqueous environment of use are disclosed.
    Type: Grant
    Filed: December 20, 2004
    Date of Patent: March 10, 2015
    Assignee: Bend Research, Inc.
    Inventors: Daniel Tod Smithey, Dwayne Thomas Friesen, Warren Kenyon Miller, Walter Christian Babcock
  • Pharmaceutical compositions with enhanced performance
    Patent number: 8940800
    Abstract: Disclosed are polymers of hydroxypropyl methyl cellulose acetate succinate (HPMCAS) and hydroxypropyl methyl cellulose acetate (HPMCA) with unique degrees of substitution of hydroxypropoxy, methoxy, acetyl, and succinoyl groups. When used in making compositions comprising a low-solubility drug and such polymers, the polymers provide enhanced aqueous concentrations and/or improved physical stability.
    Type: Grant
    Filed: June 26, 2012
    Date of Patent: January 27, 2015
    Assignee: Bend Research, Inc.
    Inventors: Walter C. Babcock, Dwayne T. Friesen, David Keith Lyon, Warren Kenyon Miller, Daniel Tod Smithey
  • Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer
    Patent number: 8703204
    Abstract: A pharmaceutical composition comprises nanoparticles comprising a cholesteryl ester transfer protein inhibitor and a poorly aqueous soluble non-ionizable polymer.
    Type: Grant
    Filed: April 23, 2008
    Date of Patent: April 22, 2014
    Assignee: Bend Research, Inc.
    Inventors: Corey Jay Bloom, Marshall David Crew, Daniel Tod Smithey, Warren Kenyon Miller, Michael Mark Morgen
  • Pharmaceutical compositions with enhanced performance
    Patent number: 8617604
    Abstract: Pharmaceutical compositions of a low-solubility drug and lower alkanoate-, phthalate- and trimellitate esters of hydroxypropyl methyl cellulose and lower alkanoate- and succinate esters of cellulose and methyl cellulose are disclosed that provide enhanced concentrations of the drug in a use environment.
    Type: Grant
    Filed: January 23, 2006
    Date of Patent: December 31, 2013
    Assignee: Bend Research, Inc.
    Inventors: Walter Christian Babcock, Dwayne Thomas Friesen, David Kenneth Lyon, Warren Kenyon Miller, Daniel Tod Smithey
  • Nanoparticles comprising a drug, ethylcellulose, and a bile salt
    Patent number: 8309129
    Abstract: A pharmaceutical composition comprises nanoparticles comprising a poorly water-soluble drug, ethylcellulose, and a bile salt.
    Type: Grant
    Filed: April 21, 2008
    Date of Patent: November 13, 2012
    Assignee: Bend Research, Inc.
    Inventors: Warren Kenyon Miller, Michael Mark Morgen, Daniel Tod Smithey
  • PHARMACEUTICAL COMPOSITIONS WITH ENHANCED PERFORMANCE
    Publication number: 20120264833
    Abstract: Disclosed are polymers of hydroxypropyl methyl cellulose acetate succinate (HPMCAS) and hydroxypropyl methyl cellulose acetate (HPMCA) with unique degrees of substitution of hydroxypropoxy, methoxy, acetyl, and succinoyl groups. When used in making compositions comprising a low-solubility drug and such polymers, the polymers provide enhanced aqueous concentrations and/or improved physical stability.
    Type: Application
    Filed: June 26, 2012
    Publication date: October 18, 2012
    Inventors: Walter C. Babcock, Dwayne T. Friesen, David Keith Lyon, Warren Kenyon Miller, Daniel Tod Smithey
  • Pharmaceutical compositions with enhanced performance
    Patent number: 8207232
    Abstract: Disclosed are polymers of hydroxypropyl methyl cellulose acetate succinate (HPMCAS) and hydroxypropyl methyl cellulose acetate (HPMCA) with unique degrees of substitution of hydroxypropoxy, methoxy, acetyl, and succinoyl groups. When used in making compositions comprising a low-solubility drug and such polymers, the polymers provide enhanced aqueous concentrations and/or improved physical stability.
    Type: Grant
    Filed: May 18, 2005
    Date of Patent: June 26, 2012
    Assignee: Bend Research, Inc.
    Inventors: Walter C. Babcock, Dwayne T. Friesen, David Keith Lyon, Warren Kenyon Miller, Daniel Tod Smithey
  • NANOPARTICLES COMPRISING A NON-IONIZABLE CELLULOSIC POLYMER AND AN AMPHIPHILIC NON-IONIZABLE BLOCK COPOLYMER
    Publication number: 20100323014
    Abstract: A pharmaceutical composition comprises nanoparticles comprising a poorly water-soluble drug, a poorly aqueous soluble non-ionizable cellulosic polymer, and a poorly aqueous soluble polymeric amphiphilic non-ionizable block copolymer.
    Type: Application
    Filed: May 26, 2008
    Publication date: December 23, 2010
    Inventors: Corey Jay Bloom, Marshall David Crew, Warren Kenyon Miller, Michael Mark Morgen, Daniel Tod Smithey
  • PHARMACEUTICAL COMPOSITIONS COMPRISING NANOPARTICLES AND A RESUSPENDING MATERIAL
    Publication number: 20100310663
    Abstract: A pharmaceutical composition comprises nanoparticles comprising a poorly water-soluble drug and a poorly aqueous soluble polymer, and a resuspending material selected from the group consisting of hydroxypropyl methyl cellulose acetate succinate, carboxymethyl ethylcellulose, and pharmaceutically acceptable salt forms thereof.
    Type: Application
    Filed: December 5, 2008
    Publication date: December 9, 2010
    Inventors: Warren Kenyon Miller, Daniel Smithey, Benjamin Lee Frankamp, Ralph Tadday
  • NANOPARTICLES COMPRISING A NON-IONIZABLE POLYMER AND AN AMINE-FUNCTIONALIZED METHACRYLATE COPOLYMER
    Publication number: 20100297237
    Abstract: A pharmaceutical composition comprises nanoparticles comprising a poorly water soluble drug, a poorly aqueous soluble non-ionizable polymer, and an amine-functionalized methacrylate copolymer.
    Type: Application
    Filed: December 5, 2008
    Publication date: November 25, 2010
    Applicant: Bend Research, Inc.
    Inventors: Corey J. Bloom, Marshall David Crew, Warren Kenyon Miller
  • NANOPARTICLES COMPRISING A NON-IONIZABLE POLYMER AND AN ANIONIC CELLULOSIC POLYMER
    Publication number: 20100266692
    Abstract: A pharmaceutical composition comprises nanoparticles comprising a poorly water soluble drug, a poorly aqueous soluble non-ionizable polymer, and an anionic cellulosic polymer.
    Type: Application
    Filed: June 30, 2008
    Publication date: October 21, 2010
    Inventors: Corey Jay Bloom, Marshall David Crew, Warren Kenyon Miller, Daniel Tod Smithey
  • NANOPARTICLES COMPRISING IONIZABLE, POORLY WATER SOLUBLE CELLULOSIC POLYMERS
    Publication number: 20100215747
    Abstract: A pharmaceutical composition comprises nanoparticles comprising ionizable, poorly water soluble cellulosic polymers.
    Type: Application
    Filed: June 30, 2008
    Publication date: August 26, 2010
    Inventors: Corey Jay Bloom, Marshall David Crew, Dwayne T. Friesen, Warren Kenyon Miller, Michael Mark Morgen, Daniel Tod Smithey