Abstract: In alternative embodiments, provided are methods for treating and ameliorating a cancer, or recurrence of a cancer such as acute myeloid leukemia (AML) comprising administration to an individual in need thereof a pharmaceutical composition comprising 17S-FD-895 (or rebecsinib) and second drug such as an ATP-competitive protein tyrosine kinase inhibitor such as dasatinib. In alternative embodiments, provided are methods for the in vivo inhibition of myeloproliferative neoplasm (MPN) or AML stem cell propagation comprising administration to an individual in need thereof a pharmaceutical composition comprising 17S-FD-895 and second drug. In alternative embodiments, provided are methods for the in vivo inhibition pre-leukemia stem cell (pre-LSC) transformation into leukemia stem cells (LSCs) comprising administration to an individual in need thereof a pharmaceutical composition comprising 17S-FD-895 and second drug.

Abstract: Secure user authentication using a OTP involve pre-storing an application on a first device for generating a valid OTP for the user responsive to receiving entry of a valid PIN, no part of the valid PIN is stored on the first device and pre-storing on a back-end server the valid PIN and a valid shared secret for the user. Upon receiving entry of a purported PIN, a purported shared secret is dynamically synthesized on the first device by the application based on the purported PIN and a purported OTP is generated on the first device. When entry of the purported OTP is received by the server in an attempt to log on the server from a second device, the server cryptographically calculates a window of OTPs, and logs on to the server from the second device is allowed if the calculated window of OTPs corresponds to the received OTP.

Abstract: Removal NO.sub.x and SO.sub.x from the flue gas utilizing a transport line adsorber through which sorbent is transported by pressurized flue gas to cause the sorbent to absorb NO.sub.x and SO.sub.x from the flue gas while the flue gas is transporting the sorbent particles through the transport line adsorber. A plurality of interconnected cyclones may be utilized to contact sorbent saturated with NO.sub.x and SO.sub.x removed from the flue gas with a heated gas to heat the sorbent and remove the NO.sub.x from the sorbent and separate the sorbent and the heated gas to produce an off stream of heated gas carrying the removed NO.sub.x away; the heated gas and gravity combine to pass the sorbent through the plurality of cyclones and which cyclones are positioned vertically and successively downwardly with respect to each other. A plurality of interconnected cyclones is also utilized to contact heated sorbent having the NO.sub.x and SO.sub.

Abstract: Removal of NO.sub.x and SO.sub.x from flue gas utilizing a transport line adsorber through which sorbent is transported by pressurized flue gas to cause the sorbent to adsorb NO.sub.x and SO.sub.x from the flue gas while the flue gas is transporting the sorbent through the transport line adsorber A plurality of interconnected cyclones is utilized to contact sorbent saturated with NO.sub.x and SO.sub.x removed from the flue gas with a heated gas to heat the sorbent and remove the NO.sub.x from the sorbent and separate the sorbent and the heated gas to produce an off stream of heated gas carrying the removed NO.sub.x away; the heated gas and gravity combine to pass the sorbent through the plurality of cyclones and which cyclones are positioned vertically and successively downwardly with respect to each other. A plurality of interconnected cyclones is also utilized to contact heated sorbent having the NO.sub.x and SO.sub.