Abstract: An object of the present invention is to provide a compound that has a specific chemical structure having an activation effect on SIRT6 and is useful as an active component for preventing and treating inflammatory diseases, and the present invention relates to a compound represented by Formula (1) or a pharmaceutically acceptable salt thereof, where each symbol in Formula (1) has the same definition as that described in the specification.

Abstract: An object of the present invention is to provide a compound having an anti-inflammatory activity or a pharmacologically acceptable salt thereof. The solution of the present invention is a compound of general formula (1) or a pharmacologically acceptable salt thereof. wherein the symbols in the formula are defined below: R1: e.g., a C1-C6 alkyl group; R2: a C1-C6 alkyl group; A: e.g., an oxygen atom; and R3: e.g., a C1-C6 alkyl group.

Abstract: A locking mechanism includes a first member that is provided on one side to lock and is rotated about a rotating shaft, a second member that is provided on the other side to lock and comes into contact with the first member to rotate the first member, a rotation applying member that further applies a rotational force to the first member rotated by the second member, a restriction portion that restricts movement of the first member to be rotated in a direction in which the first member is released from a locked state, and an elastic portion that allows the first member and the restriction portion to be in elastic contact with each other and allows the first member and the restriction portion to start to be in elastic contact with each other before the first member rotated by the second member is further rotated by the rotation applying member in a release direction which is the direction in which the first member is released from the locked state.

Abstract: An apparatus includes a housing, a cover that is opened and closed on the housing, a detection part that detects opening and closing of the cover using ON and OFF, a rotating part that is rotatably supported and turns on and off the detection part, a pushing portion that comes into contact with the rotating part to rotate the rotating part in a case where the cover is closed, and a rotation applying part that applies a rotational force to the rotating part rotated by the pushing portion in a direction in which the detection part is turned on in a case where the cover is closed.

Abstract: An image forming apparatus includes a rotatable image bearing member and a rotatable developing member to carry developer made up of toner particles and carrier particles adhered to surfaces of the toner particles. Where a pressing force pressing the developing member against the image bearing member is F1, a total number of the carrier particles interposed between the toner particles and the image bearing member is N1, and an adhesion Ft between a carrier particle and a toner particle, measured when the carrier particle is pressed against the toner particle with F1/N1 that is a pressing force per unit carrier particle, and an adhesion Fdr1 between the carrier particle and the image bearing member, measured when the carrier particle is pressed against the image bearing member with F1/N1, satisfy Ft?Fdr1.

Abstract: This non-oriented electrical steel sheet includes a base material having a chemical composition including Si: 3.7 to 4.8%, wherein a recrystallization rate is less than 100% in terms of an area fraction, the following Formula (i) and Formula (ii) are satisfied, and the tensile strength is more than 700 MPa. 4.3?Si+sol. Al+0.5×Mn?4.9??(i) (B50(0°)+2×B50(45°)+B50(90°))/4?1.

Abstract: In a traffic flow control system, communication is performed with a travel control device of a moving body passing through a transportation route and the traffic flow of the transportation route is controlled. The traffic control system includes an entry authority management unit and a communication unit. In a transportation route divided into virtual areas, the entry authority management unit manages entry authority for each area, managing tokens in a number that corresponds to the area, and guiding entry of the moving body to the area by attaching entry authority to a token and delivering the resulting token to the travel control device. The communication unit communicates the entry authority and tokens to the travel control device.

Abstract: A baseball catcher's chest protector includes a base member, a cover member, and a cushioning member. The cover member is attached to the base member. The cushioning member is attached to the base member and is sandwiched between the base member and the cover member. The cushioning member includes a foundation and a plurality of protrusions. The plurality of protrusions protrude from the foundation. The foundation has a first surface and a second surface. The first surface faces the base member. The second surface is arranged opposite to the base member with respect to the first surface and faces the cover member. Each of the plurality of protrusions protrudes from the second surface toward the cover member and the plurality of protrusions are arranged with a space being interposed between the plurality of protrusions.

Abstract: In a traffic flow control system, communication is performed with a travel control device of a moving body passing through a transportation route and the traffic flow of the transportation route is controlled. The traffic control system includes an entry authority management unit and a communication unit. In a transportation route divided into virtual areas, the entry authority management unit manages entry authority for each area, managing tokens in a number that corresponds to the area, and guiding entry of the moving body to the area by attaching entry authority to a token and delivering the resulting token to the travel control device. The communication unit communicates the entry authority and tokens to the travel control device.

Abstract: An information processing system for controlling movements of a character (200) in a virtual three-dimensional space, comprising movement control unit (231) that controls the movements of the character (200), and a switching determination unit (232) that determines switching of the movement of the character (200) by the movement control unit (231) between a three-dimensional movement in the virtual three-dimensional space and a movement in a predetermined surface (211) provided in the virtual three-dimensional space. The movement control unit (231) determines a speed of the character (200) after the switching on the basis of a speed of the character (200) before the switching when the switching is performed between the three-dimensional movement in the virtual three-dimensional space and the movement in the predetermined surface (211).

Abstract: A reversing assistance device suited for a mining dump truck measures a first distance to a first object, which exists at a first height comprising a trajectory of a rear wheel of the dump truck during reversing, and a second distance to a second object, which exists at a second height comprising a trajectory of a vessel during the reversing, for computing the position of the first object. If the distance between the position of the first object and a designated loading position designated by an operator of a loading machine is equal to or smaller than a threshold, the first object is determined to be an approachable object, a smaller one of the first distance and the second distance is determined as a target stop distance, and based on the target stop distance, a target stop position is computed.

Abstract: A switch includes: a first electrode sheet including a first electrode; a second electrode sheet including a second electrode that faces the first electrode sheet; and an adhesive that includes a first opening through which the first electrode faces the second electrode sheet and that attaches the first electrode sheet to the second electrode sheet. The first electrode sheet includes: a first substrate on which the first electrode is disposed; a first spacer between the first substrate and the second electrode sheet that includes a second opening at a position corresponding to the first electrode; and a first base between the first substrate and the first spacer that overlaps at least a portion of an edge of the first opening of the adhesive. The first spacer is attached to the second electrode sheet by the adhesive.

Abstract: A switch includes: a first electrode sheet including a first electrode; a second electrode sheet including a second electrode that faces the first electrode sheet; and an adhesive that includes a first opening through which the first electrode faces the second electrode sheet and that attaches the first electrode sheet to the second electrode sheet. The first electrode sheet includes: a first substrate on which the first electrode is disposed; a first spacer between the first substrate and the second electrode sheet that includes a second opening at a position corresponding to the first electrode; and a first base between the first substrate and the first spacer that overlaps at least a portion of an edge of the first opening of the adhesive. The first spacer is attached to the second electrode sheet by the adhesive.

Abstract: An information processing system for controlling movements of a character (200) in a virtual three-dimensional space, comprising movement control unit (231) that controls the movements of the character (200), and a switching determination unit (232) that determines switching of the movement of the character (200) by the movement control unit (231) between a three-dimensional movement in the virtual three-dimensional space and a movement in a predetermined surface (211) provided in the virtual three-dimensional space. The movement control unit (231) determines a speed of the character (200) after the switching on the basis of a speed of the character (200) before the switching when the switching is performed between the three-dimensional movement in the virtual three-dimensional space and the movement in the predetermined surface (211).

Abstract: A protected region is set for a manned working machine, said region including a first protected region in which new protected region setting request information is not transmitted and which includes the position of the manned working machine, and a second protected region which is set along a periphery of the first protected region and in which new protected region setting request information is transmitted. An area occupied by the vehicle body of the manned working machine on a plane projected on the ground surface is calculated on the basis of vehicle body information indicating the size of the vehicle body of the manned working machine and position information thereof. When the occupied area is present within the first protected region, new protected region setting request information is not transmitted, whereas when the occupied area is present within the second protected region, protected region setting request information is transmitted.

Abstract: An information processing system for controlling movements of a character (200) in a virtual three-dimensional space, comprising movement control unit (231) that controls the movements of the character (200), and a switching determination unit (232) that determines switching of the movement of the character (200) by the movement control unit (231) between a three-dimensional movement in the virtual three-dimensional space and a movement in a predetermined surface (211) provided in the virtual three-dimensional space. The movement control unit (231) determines a speed of the character (200) after the switching on the basis of a speed of the character (200) before the switching when the switching is performed between the three-dimensional movement in the virtual three-dimensional space and the movement in the predetermined surface (211).

Abstract: A membrane switch includes an upper electrode sheet that includes an upper electrode, a lower electrode sheet that includes a lower electrode facing the upper electrode, and an adhesive layer that joins the upper electrode sheet to the lower electrode sheet; and the upper and lower electrodes come into contact with each other due to a pressing force, which is applied to at least one of the upper electrode sheet and the lower electrode sheet, and conduct electricity. The upper electrode sheet includes: an upper base on which the upper electrode is formed; and an upper insulating layer that is provided between the upper base and the lower electrode sheet, includes a first opening at a position corresponding to the upper electrode, and is joined to the lower electrode sheet by the adhesive layer. The upper insulating layer is formed on the upper base.

Abstract: A first measuring device measures a location of its own vehicle relative to each feature point on a surrounding structure around a road surface on which the vehicle. A first feature-point is provided which, based on output from the first measuring device, acquires coordinates of the each feature point expressed in a coordinate system of the first measuring device, and uses a self-location to convert the coordinates into an external coordinate. A feature-point trajectory generation section is provided to generate, based on the first coordinates, a trajectory of the feature point group. A second measuring device measures a location of its own vehicle relative to a feature point located rearward of the feature point measured by the first measuring device. An anomaly determination section is provided to determine that anomaly occurs in a self-location estimation device if the second coordinates are on the trajectory.

Abstract: A game system (1) includes a player object state determination unit (721) that determines the state of a player object in a virtual space, a search range determination unit (722) that determines a search range for searching for a non-player object based on the state of the player object, a target-object presence determination unit (723) that determines whether the non-player object is present in the search range, and a target-object setting unit (724) that sets the non-player object as a target of a cap throwing process if it is determined that the non-player object is present in the search range.

Abstract: A game system includes an input receiving unit (71) that receives input by a player, an operated character changing unit (722) that changes an object to be assigned as an operated object that is operated in response to the input received with the input receiving unit (71) among objects in a virtual space between a PC and an NPC, and an NPC control unit (723) that controls the NPC using a first control method while the NPC is not assigned as the operated object. During a period until a predetermined condition is satisfied after an object to serve as the operated object is changed from the NPC to the PC by the operated character changing unit (722), the NPC control unit (723) controls the NPC using a second control method different from the first control method.