Patents by Inventor Wayne Frederick Reed
Wayne Frederick Reed has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11971361Abstract: Devices and methods for characterization and control of biopolymers and synthetic polymers during manufacturing. The device may include a body defining a fluid flow path. The body may be configured to receive a process flow liquid such that the process flow liquid may flow through an interior portion of the body. The body may also include a plurality of detectors inserted into said body, each of the plurality of detectors configured to monitor one or more process characteristics.Type: GrantFiled: August 10, 2018Date of Patent: April 30, 2024Assignee: YOKOGAWA FLUENCE ANALYTICS, INC.Inventors: Wayne Frederick Reed, Michael Felix Drenski, Alex W. Reed
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Patent number: 11940384Abstract: Devices and methods for determining the cumulative distribution of a polymer property in a reactor without physical separation of reaction subcomponents. The device includes a means of measuring an instantaneous property of the polymers being produced in a reaction vessel a plurality of times during a polymerization reaction as well as a means of determining the corresponding change in polymer concentration in the reaction vessel between measurements of the instantaneous polymer property. The device also includes a means of computing a statistical distribution appropriate to the polymer characteristic and applying the statistical distribution to a recently measured instantaneous value of the polymer property so as to have an instantaneous distribution of the polymer property and a means of adding together the instantaneous distributions of the polymer property in order to obtain the cumulative distribution of the polymer property in the reactor.Type: GrantFiled: September 23, 2022Date of Patent: March 26, 2024Assignees: Yokogawa Fluence Analytics, Inc., THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUNDInventors: Wayne Frederick Reed, Rick D. Montgomery, Michael Felix Drenski, Aide Wu
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Publication number: 20230144017Abstract: Devices and methods for determining the cumulative distribution of a polymer property in a reactor without physical separation of reaction subcomponents. The device includes a means of measuring an instantaneous property of the polymers being produced in a reaction vessel a plurality of times during a polymerization reaction as well as a means of determining the corresponding change in polymer concentration in the reaction vessel between measurements of the instantaneous polymer property. The device also includes a means of computing a statistical distribution appropriate to the polymer characteristic and applying the statistical distribution to a recently measured instantaneous value of the polymer property so as to have an instantaneous distribution of the polymer property and a means of adding together the instantaneous distributions of the polymer property in order to obtain the cumulative distribution of the polymer property in the reactor.Type: ApplicationFiled: September 23, 2022Publication date: May 11, 2023Inventors: Wayne Frederick REED, Rick D. MONTGOMERY, Michael Felix DRENSKI, Aide WU
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Patent number: 11532381Abstract: Method, device, and system for identifying a model-based time dependent light scattering signature that includes receiving an experimental time dependent light scattering signature comprising experimental data descriptive of an average molecular weight of protein components in a solution over time. The method further includes identifying an Ansatz for evaluating the experimental time dependent light scattering signature, the Ansatz being an initial model-based time dependent light scattering signature, the initial model-based time dependent light scattering signature identifying at least one key variable. The method also includes adjusting the at least one key variable in the initial model-based time dependent light scattering signature until a final model-based time dependent light scattering signature is identified. In some instances, the final model-based time dependent light scattering signature identifies at least one protein aggregation mechanism.Type: GrantFiled: January 12, 2017Date of Patent: December 20, 2022Assignees: ADVANCED POLYMER MONITORING TECHNOLOGIES, INC., THE ADMINISTRATORS OF THE TULANE EDUCATION FUNDInventors: Wayne Frederick Reed, Daniel J. Rees
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Patent number: 11474044Abstract: Devices and methods for determining the cumulative distribution of a polymer property in a reactor without physical separation of reaction subcomponents. The device includes a means of measuring an instantaneous property of the polymers being produced in a reaction vessel a plurality of times during a polymerization reaction as well as a means of determining the corresponding change in polymer concentration in the reaction vessel between measurements of the instantaneous polymer property The device also includes a means of computing a statistical distribution appropriate to the polymer characteristic and applying the statistical distribution to a recently measured instantaneous value of the polymer property so as to have an instantaneous distribution of the polymer property and a means of adding together the instantaneous distributions of the polymer property in order to obtain the cumulative distribution of the polymer property in the reactor.Type: GrantFiled: April 21, 2017Date of Patent: October 18, 2022Assignees: ADVANCED POLYMER MONITORING TECHNOLOGIES, INC., THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUNDInventors: Wayne Frederick Reed, Rick D. Montgomery, Michael Felix Drenski, Aide Wu
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Patent number: 10837912Abstract: Manual and automatic methods and devices using a ACOMP system for active control of polymerization reaction processes. An ideal desired trajectory of one or more reaction and polymer characteristics can be established to produce a desired final polymer product with specified characteristics from a polymerization reaction process. A current reaction trajectory of a polymerization reaction process can be driven to an ideal or desired reaction trajectory. In a manual embodiment an operator can use ACOMP data to adjust process variables in order to drive the current reaction trajectory toward the ideal or desired reaction trajectory. In an automated mode a control program can use ACOMP data to make adjustments to process variables to drive the polymerization reaction process toward the desired trajectory as closely as possible either empirically or by solving the governing equations for the polymerization reaction process.Type: GrantFiled: September 30, 2015Date of Patent: November 17, 2020Assignees: ADVANCED POLYMER MONITORING TECHNOLOGIES, INC., THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUNDInventors: Wayne Frederick Reed, Michael Felix Drenski
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Publication number: 20200200686Abstract: Devices and methods for characterization and control of biopolymers and synthetic polymers during manufacturing. The device may include a body defining a fluid flow path. The body may be configured to receive a process flow liquid such that the process flow liquid may flow through an interior portion of the body. The body may also include a plurality of detectors inserted into said body, each of the plurality of detectors configured to monitor one or more process characteristics.Type: ApplicationFiled: August 10, 2018Publication date: June 25, 2020Inventors: Wayne Frederick REED, Michael Felix DRENSKI, Alex W. REED
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Patent number: 10620127Abstract: Devices and methods for controlling the properties of chemical species during time-dependent processes. A device includes a reactor for containing one or more chemical species of a time-dependent process, an extraction pump for automatically and continuously extracting an amount of the one or more chemical species from the reactor, one or more detectors for measuring property changes of the one or more extracted chemical species and generating a continuous stream of data related to the one or more property changes to the one or more chemical species during a time interval, and a process controller configured to fit the continuous stream of data to a mathematical function to predict one or more properties of the one or more chemical species at a future time point and make one or more process decisions based on the prediction of one or more properties at the future time point.Type: GrantFiled: January 22, 2019Date of Patent: April 14, 2020Assignees: THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, ADVANCED POLYMER MONITORING TECHNOLOGIES, INC.Inventors: Wayne Frederick Reed, Michael Felix Drenski
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Publication number: 20190194360Abstract: Devices and methods for actively controlling the production of multistage and multimodal polymers. The device may include a reaction vessel configured to contain a polymer solution and generate polymer reactions in at least two stages as well as one or more detectors configured to monitor at least one reaction characteristic of the polymer solution contained in the reaction vessel. The device may further include a controller coupled with the reaction vessel and the one or more detectors, the controller configured to actively control the development of a predetermined reaction characteristic by modifying at least one process control variable based on the at least one reaction characteristic monitored by the detector.Type: ApplicationFiled: August 31, 2017Publication date: June 27, 2019Applicant: ADVANCED POLYMER MONITORING TECHNOLOGIES, INC., DBA / FLUENCE ANALYTICSInventors: Wayne Frederick REED, Michael Felix DRENSKI, Natalie LEONARDI
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Publication number: 20190154588Abstract: Devices and methods for controlling the properties of chemical species during time-dependent processes. A device includes a reactor for containing one or more chemical species of a time-dependent process, an extraction pump for automatically and continuously extracting an amount of the one or more chemical species from the reactor, one or more detectors for measuring property changes of the one or more extracted chemical species and generating a continuous stream of data related to the one or more property changes to the one or more chemical species during a time interval, and a process controller configured to fit the continuous stream of data to a mathematical function to predict one or more properties of the one or more chemical species at a future time point and make one or more process decisions based on the prediction of one or more properties at the future time point.Type: ApplicationFiled: January 22, 2019Publication date: May 23, 2019Inventors: Wayne Frederick Reed, Michael Felix Drenski
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Publication number: 20190128812Abstract: Devices and methods for determining the cumulative distribution of a polymer property in a reactor without physical separation of reaction subcomponents. The device includes a means of measuring an instantaneous property of the polymers being produced in a reaction vessel a plurality of times during a polymerization reaction as well as a means of determining the corresponding change in polymer concentration in the reaction vessel between measurements of the instantaneous polymer property The device also includes a means of computing a statistical distribution appropriate to the polymer characteristic and applying the statistical distribution to a recently measured instantaneous value of the polymer property so as to have an instantaneous distribution of the polymer property and a means of adding together the instantaneous distributions of the polymer property in order to obtain the cumulative distribution of the polymer property in the reactor.Type: ApplicationFiled: April 21, 2017Publication date: May 2, 2019Inventors: Wayne Frederick REED, Rick D. MONTGOMERY, Michael Felix DRENSKI, Aide WU
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Publication number: 20190086437Abstract: Devices and methods for rapidly and incrementally or continuously, measuring rheological properties of polymers under different shear rates. The device includes a pump configured to accept a continuous stream of sample solution during an interval of time, an injector configured to inject a flow of the sample solution through two or more viscometers, and a computing and processing device configured to monitor and measure rheological properties of the solution under at least two shear rates simultaneously in the two or more viscometers.Type: ApplicationFiled: March 7, 2017Publication date: March 21, 2019Inventors: Wayne Frederick REED, Alex REED, Michael Felix DRENSKI
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Patent number: 10197500Abstract: Devices and methods for controlling the properties of chemical species during time-dependent processes. A device includes a reactor for containing one or more chemical species of a time-dependent process, an extraction pump for automatically and continuously extracting an amount of the one or more chemical species from the reactor, one or more detectors for measuring property changes of the one or more extracted chemical species and generating a continuous stream of data related to the one or more property changes to the one or more chemical species during a time interval, and a process controller configured to fit the continuous stream of data to a mathematical function to predict one or more properties of the one or more chemical species at a future time point and make one or more process decisions based on the prediction of one or more properties at the future time point.Type: GrantFiled: January 19, 2016Date of Patent: February 5, 2019Assignees: ADVANCED POLYMER MONITORING TECHNOLOGIES, INC., THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUNDInventors: Wayne Frederick Reed, Michael Felix Drenski
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Publication number: 20190025178Abstract: Method, device, and system for identifying a model-based time dependent light scattering signature that includes receiving an experimental time dependent light scattering signature comprising experimental data descriptive of an average molecular weight of protein components in a solution over time. The method further includes identifying an Ansatz for evaluating the experimental time dependent light scattering signature, the Ansatz being an initial model-based time dependent light scattering signature, the initial model-based time dependent light scattering signature identifying at least one key variable. The method also includes adjusting the at least one key variable in the initial model-based time dependent light scattering signature until a final model-based time dependent light scattering signature is identified. In some instances, the final model-based time dependent light scattering signature identifies at least one protein aggregation mechanism.Type: ApplicationFiled: January 12, 2017Publication date: January 24, 2019Inventors: Wayne Frederick Reed, Daniel J. Rees
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Publication number: 20180224473Abstract: A device, method, and system for scheduling the analytical testing and throughput of macromolecular solutions based on light scattering measurements of one or more time dependent macromolecular solution characteristics. A device that includes a plurality of monitoring reservoirs, each configured to receive a macromolecular solution sample, coupled to a light scattering detection instrument configured to monitor light scattering from the plurality of macromolecular solution samples. The device further includes a computing device configured to measure a predetermined time dependent solution characteristic based on the monitored light scattering data and further configured to determine a time for performing an operation on one or more of the macromolecular solution samples based on the predetermined time dependent characteristic measurement.Type: ApplicationFiled: July 21, 2016Publication date: August 9, 2018Inventor: Wayne Frederick Reed
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Publication number: 20180011024Abstract: Devices and methods for controlling the properties of chemical species during time-dependent processes. A device includes a reactor for containing one or more chemical species of a time-dependent process, an extraction pump for automatically and continuously extracting an amount of the one or more chemical species from the reactor, one or more detectors for measuring property changes of the one or more extracted chemical species and generating a continuous stream of data related to the one or more property changes to the one or more chemical species during a time interval, and a process controller configured to fit the continuous stream of data to a mathematical function to predict one or more properties of the one or more chemical species at a future time point and make one or more process decisions based on the prediction of one or more properties at the future time point.Type: ApplicationFiled: January 19, 2016Publication date: January 11, 2018Inventors: Wayne Frederick Reed, Michael Felix Drenski
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Publication number: 20170212054Abstract: Manual and automatic methods and devices using a ACOMP system for active control of polymerization reaction processes. An ideal desired trajectory of one or more reaction and polymer characteristics can be established to produce a desired fmal polymer product with specified characteristics from a polymerization reaction process. A current reaction trajectory of a polymerization reaction process can be driven to an ideal or desired reaction trajectory. In a manual embodiment an operator can use ACOMP data to adjust process variables in order to drive the current reaction trajectory toward the ideal or desired reaction trajectory. In an automated mode a control program can use ACOMP data to make adjustments to process variables to drive the polymerization reaction process toward the desired trajectory as closely as possible either empirically or by solving the governing equations for the polymerization reaction process.Type: ApplicationFiled: September 30, 2015Publication date: July 27, 2017Inventors: Wayne Frederick Reed, Michael Felix Drenski
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Patent number: 9664608Abstract: Simultaneous Multiple Sample Light Scattering systems and methods can be used for polymer stability testing and for applying stressors to polymer or colloid solutions including heat stress, ultrasound, freeze/thaw cycles, shear stress and exposure to different substances and surfaces, among others, that create a polymer stress response used to characterize the polymer solution and stability.Type: GrantFiled: August 20, 2014Date of Patent: May 30, 2017Assignees: ADVANCED POLYMER MONITORING TECHNOLOGIES, INC., THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUNDInventors: Wayne Frederick Reed, Michael Felix Drenski, Alex Wayne Reed
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Publication number: 20150056710Abstract: Simultaneous Multiple Sample Light Scattering systems and methods can be used to for polymer stability testing and for applying stressors to polymer or colloid solutions including heat stress, ultrasound, freeze/thaw cycles, shear stress and exposure to different substances and surfaces. among others, that create a polymer stress response used to characterize the polymer solution and stability.Type: ApplicationFiled: August 20, 2014Publication date: February 26, 2015Applicants: ADVANCED POLYMER MONITORING TECHNOLOGIES, INC., THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUNDInventors: Wayne Frederick Reed, Michael Felix Drenski, Alex Wayne Reed