Patents by Inventor Wayne R. Heitmann

Wayne R. Heitmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process and intermediate for the preparation of terazosin hydrochloride dihydrate
    Patent number: 5504207
    Abstract: A process for the preparation of 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride (terazosin hydrochloride dihydrate comprises the steps of reacting 4-amino-2-chloro-6,7-dimethoxy-quinazoline with N-(2-tetrahydrofuroyl)piperazine in an anhydrous polar organic solvent in the absence of an added acid scavenger to produce anhydrous 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride (Form IV) and thereafter converting the product of that step to 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)-piperazine hydrochloride dihydrate.
    Type: Grant
    Filed: October 18, 1994
    Date of Patent: April 2, 1996
    Assignee: Abbott Laboratories
    Inventors: Anthony Mannino, Rodger F. Henry, Wayne R. Heitmann, Bruce W. Horrom
  • Process for making 4-aroyl-substituted phenoxyacetic acids
    Patent number: 4220801
    Abstract: 2,3-Dichloro-4-(hydroxybenzoyl)phenoxyacetic acid, its analogs and their salts are powerful uricosuric diuretics; they can be made in a one-pot reaction from a loweralkyl 2,3-dichloro-4-(nitrobenzoyl)phenoxyacetate or its analogs.
    Type: Grant
    Filed: July 23, 1979
    Date of Patent: September 2, 1980
    Assignee: Abbott Laboratories
    Inventors: Roland L. Walters, Wayne R. Heitmann
  • Process for making N-(2-methyl-1-naphthyl)-maleimide
    Patent number: 4217282
    Abstract: A practical method for making N-(2-methyl-1-naphthyl)-maleimide has been discovered; it requires the use of specific solvents and acid catalysts which produce the desired compound in good yield and highly acceptable purity.
    Type: Grant
    Filed: February 21, 1979
    Date of Patent: August 12, 1980
    Assignee: Abbott Laboratories
    Inventor: Wayne R. Heitmann